Immune System News and Research

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Neutrolis announces development of first-in-class therapy to target NETs in COVID-19 patients

Neutrolis, a biotechnology company developing therapeutics that target neutrophils, the most abundant immune cells in the body, today announced the development of NTR-441, a first-in-class DNASE1L3 enzyme analog that has the potential to rapidly and systemically clear neutrophil extracellular traps for severe cases of COVID-19.

5 Aug 2020

Regeneron's COVID-19 antibody-drug cocktail treats SARS-CoV-2 virus in animals

Now, Regeneron Pharmaceuticals says its COVID-19 antibody-drug cocktail under development prevented and treated the disease in monkeys and hamsters, showing promise that it may work in humans.

5 Aug 2020

Study: "Memory" T cells that recognize common cold coronaviruses also recognize SARS-CoV-2

Your immune system's "memory" T cells keep track of the viruses they have seen before. This immune cell memory gives the cells a headstart in recognizing and fighting off repeat invaders.

5 Aug 2020

Can Vitamin D help combat the coronavirus?

In a new report published in The Lancet, a team of researchers discussed the possibility that vitamin D could offer protection against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The meta-analyses of randomized controlled trials performed from 2007 to 2020.

4 Aug 2020

Discovery of new mechanism in the immune system provides better understanding of diseases

An active immune system protects against diseases and infections. An overactive immune system is the body's worst enemy. One example of this is multiple sclerosis, which is a so-called autoimmune disease, while an overactive immune system also leads to some COVID-19 patients becoming seriously ill.

4 Aug 2020

NIH trial to evaluate potential new therapeutics for mild, moderate COVID-19

A Phase 2 clinical trial will evaluate the safety and efficacy of potential new therapeutics for COVID-19, including an investigational therapeutic based on synthetic monoclonal antibodies (mAbs) to treat the disease.

4 Aug 2020

Researchers identify two dozen pesticides linked with mammary gland tumors

In an analysis of how regulators review pesticides for their potential to cause cancer, researchers at Silent Spring Institute identified more than two dozen registered pesticides that were linked with mammary gland tumors in animal studies.

4 Aug 2020

Clinical trial to test safety, efficacy of antibody treatment in hospitalized COVID-19 patients

Patients admitted with COVID-19 at select hospitals may now volunteer to enroll in a clinical trial to test the safety and efficacy of a potential new treatment for the disease.

4 Aug 2020

Researchers discover treatment for severe auto inflammatory syndrome

Researchers from the Icahn School of Medicine used a novel genetic sequencing technology to identify the genetic cause of--and a treatment for--a previously unknown severe auto inflam-matory syndrome affecting an 18-year-old girl since infancy.

4 Aug 2020

Maryland County pledges investigation of health worker’s coronavirus death

Officials in Maryland's Prince George's County say they "will spare no time or expense" investigating the circumstances surrounding the death of a veteran public health worker who died of COVID-19 after relatives and co-workers believe she contracted the coronavirus on the job.

4 Aug 2020

Researcher is exploring safer and more effective treatment for leukemia

A potentially safer, more effective chemotherapy treatment for patients with blood-related cancers, such as leukemia, who need a particular bone marrow transplant procedure is under study at the University of Arizona Health Sciences.

4 Aug 2020

ALKBH5 enzyme shows promising target for cancer immunotherapy

Cancer immunotherapy -; a treatment that better enables a patient's own immune system to attack tumors -; has shown great potential against some cancers. Yet immunotherapy doesn't work against all tumor types, and many patients who initially respond later develop resistance and relapse.

4 Aug 2020

A new platform to provide information on SARS-CoV-2 immunity or seroprevalence

Who has overcome an infection with the virus without noticing, and how many people have already produced protective antibodies against the new coronavirus? Various antibody studies are now under way that will provide information on immunity or seroprevalence in the population.

3 Aug 2020

Study uncovers how schistosome worms trick the host's immune system

Researchers uncovered in a new study how schistosomes, parasitic flatworms that infect more than 200 million people in the tropics, trick the host's immune system and continue producing eggs for decades.

3 Aug 2020

New biomarkers may identify Type 1 diabetes patients who could benefit from immunotherapy

Scientists at UCL have discovered new biomarkers, which may identify those people with Type 1 diabetes who would benefit from the immunotherapy drug Abatacept, a finding which could eventually help thousands manage the disease more effectively.

3 Aug 2020

Maternal vaccination could protect infants against RSV illness

Immunizing pregnant women with a potential vaccine against RSV could prevent the most common cause of pneumonia in their babies.

3 Aug 2020

Immune system's oldest branches may underpin COVID severity

One of the immune system's oldest branches, called complement, may be influencing the severity of COVID disease, according to a new study from researchers at Columbia University Irving Medical Center.

3 Aug 2020

SARS-CoV-2 spike protein recognized by innate immune receptors in a glycan-dependent way

The spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) depends on its ability to infect new host cells following its replication and release from infected cells. This pivots on its ability to bind to cell surface receptors like the ACE2 enzyme.

3 Aug 2020

FDA authorizes first two COVID-19 serology tests

Today, the U.S. Food and Drug Administration authorized the first two COVID-19 serology tests that display an estimated quantity of antibodies present in the individual's blood.

1 Aug 2020

IRB Barcelona team receives ERC grant to develop new drugs against fibrosis

The team led by Manuel Serrano, ICREA researcher and Head of the Cellular Plasticity and Disease Lab at IRB Barcelona, has been awarded the Proof of Concept grant by the European Research Council.

31 Jul 2020