B Cell News and Research

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Deficient regulators in the immune system responsible for type 1 diabetes

The main regulators of the immune system, called CD4+Treg cells, are thought to be highly involved in a large range of immune diseases.

25 Jan 2008

Building stronger bones, one stem cell at a time

Mesenchymal stem cells (MSCs) are bone marrow-derived cells that are capable of giving rise to various cell types through a process known as differentiation.

25 Jan 2008

Adult stem cell application effective in treatment of peripheric vascular disease

Multipotent adult progenitor stem cells extracted from bone marrow, and known as MAPCs, have proved to be effective in the regeneration of blood vessel tissue and also in muscle tissue when treating peripheric vascular disease.

25 Jan 2008

Synthesis of natural molecule could lead to better anti-cancer drugs

In early 2007, Northwestern University chemist Karl Scheidt's interest was piqued when marine chemist Amy Wright reported in the Journal of Natural Products that a new natural compound derived from an uncommon deep-sea sponge was extremely effective at inhibiting cancer cell growth.

24 Jan 2008

Stanford study finds transplant patient thrives 2 years after stopping immunosuppressive drugs

Luck smiled on Larry Kowalski when his brother agreed to donate a kidney Kowalski needed to live.

24 Jan 2008

Researchers identify brain's 'eureka' circuitry

Researchers have found the brain region that controls the decision to halt your midnight exploration of the refrigerator and commence enjoyment of that leftover chicken leg.

24 Jan 2008

Genetic roots of obesity

A discovery by Queen's biologists and their students sheds new light on the genetic roots of obesity a condition that is increasing dramatically in North America and has been linked to heart disease, diabetes and some forms of cancer.

24 Jan 2008

Quality control mechanism tags defective sperm cells inside the body

Defective sperm cells do not pass through the body unnoticed. A new University of Missouri study provides evidence that the body recognizes and tags defective sperm cells while they undergo maturation in the epididymis, a sperm storage gland attached to the testis.

24 Jan 2008

Northwestern Memorial trial may wean kidney transplant patients off antirejection drugs

After a transplant surgery, anti-rejection drugs for the organ recipient are a must, but with prolonged use can have serious side effects, including infections, heart disease and cancer.

24 Jan 2008

Genetic difference predicts antidepressant response

Researchers have identified subtle genetic variations that predict the efficacy of two widely used antidepressant drugs.

24 Jan 2008

Engineers use blood's hydrodynamics to manipulate stem, cancer cells

A tiny, implantable device has pulled adult stem cells out of a living rat with a far greater purity than any present technique.

24 Jan 2008

Scientists use nanoscale polymer films to control drug delivery

Using nanotechnology, scientists from UCLA and Northwestern University have developed a localized and controlled drug delivery method that is invisible to the immune system, a discovery that could provide newer and more effective treatments for cancer and other diseases.

23 Jan 2008

Researchers propose consumers buy yearly 'drug licenses' as new way to pay for prescriptions

Changing the way consumers pay for prescription drugs so that the system more closely resembles paying for cell phones or computer software could increase drug use without altering patients' out-of-pocket spending, health plan costs or drug company profits, according to a new RAND Corporation study.

23 Jan 2008

Researcher transplants stem cells to try to save patients' legs

A Northwestern University Feinberg School of Medicine researcher has launched the first U.S. trial in which a purified form of subjects' own adult stem cells was transplanted into their leg muscles with severely blocked arteries to try to grow new small blood vessels and restore circulation in their legs.

23 Jan 2008

New anticancer drugs may block HSP90-IP6K2 protein interaction involved in cell death

Johns Hopkins researchers have discovered a previously unsuspected mechanism of cell death that may afford a new way to find and develop stronger yet less-harmful anticancer drugs.

23 Jan 2008

Brain molecule from endothelial cells may be a new target for treatment of multiple sclerosis

In the February issue of Nature Immunology, the team provides fresh answers concerning the role of novel adhesion molecules in the pathogenesis of MS, a chronic autoimmune disease of the nervous system that affects approximately 55,000 young adults in Canada.

23 Jan 2008

New method for measuring protein synthesis

In a major breakthrough for future research and drug development, a team of Los Angeles Biomedical Research Institute (LA BioMed) investigators developed a new, more reliable method for measuring protein synthesis and turnover, processes that are critical to understanding cellular functions.

23 Jan 2008

Genetic switches could lower cost of producing drugs, proteins

Bacteria have evolved complex mechanisms called quorum sensing systems that provide for cell-to-cell communication, an adaptation that allows them to wait until their population grows large enough before mounting an attack on a host or competing for nutrients.

23 Jan 2008

Scientists render Ebola harmless in the laboratory

Scientists in the United States say that they have found a way to make the lethal Ebola virus harmless in the laboratory.

23 Jan 2008

Food peptides activate bitter taste receptors

Researchers from the Monell Center and Tokyo University of Agriculture have used a novel molecular method to identify chemical compounds from common foods that activate human bitter taste receptors.

23 Jan 2008

B Cell News and Research

Deficient regulators in the immune system responsible for type 1 diabetes

Building stronger bones, one stem cell at a time

Adult stem cell application effective in treatment of peripheric vascular disease

Synthesis of natural molecule could lead to better anti-cancer drugs

Stanford study finds transplant patient thrives 2 years after stopping immunosuppressive drugs

Researchers identify brain's 'eureka' circuitry

Genetic roots of obesity

Quality control mechanism tags defective sperm cells inside the body

Northwestern Memorial trial may wean kidney transplant patients off antirejection drugs

Genetic difference predicts antidepressant response

Engineers use blood's hydrodynamics to manipulate stem, cancer cells

Scientists use nanoscale polymer films to control drug delivery

Researchers propose consumers buy yearly 'drug licenses' as new way to pay for prescriptions

Researcher transplants stem cells to try to save patients' legs

New anticancer drugs may block HSP90-IP6K2 protein interaction involved in cell death

Brain molecule from endothelial cells may be a new target for treatment of multiple sclerosis

New method for measuring protein synthesis

Genetic switches could lower cost of producing drugs, proteins

Scientists render Ebola harmless in the laboratory

Food peptides activate bitter taste receptors

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