Immune System News and Research

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A coronavirus vaccine: Where does it stand?

More than four months into the coronavirus pandemic, how close are the U.S. and the world to a safe and effective vaccine? Scientists say they see steady progress and are expressing cautious optimism that a vaccine could be ready by spring.

16 Jul 2020

Study shows how parasitic bacteria cause lesions in the skin and internal organs

Bacteria of the genus Bartonella are parasites that can be transmitted to humans via insect bites and animal scratches, resulting in an infection known as "bartonellosis."

16 Jul 2020

Prominent pharmacologist calls for new approach to treat COVID-19

A prominent Australian pharmacologist has called for a new approach to treating COVID-19 as hopes fade of finding an effective vaccine or antiviral before the end of the year.

16 Jul 2020

Children with MIS-C have different antibody responses than adults with COVID-19

A new study published on the preprint medRxiv in July 2020 reveals that children with the condition Multisystem Inflammatory Syndrome in Children (MIS-C) have a distinctly different pattern of antibody generation compared to adults with COVID-19 disease.

16 Jul 2020

New immune profiles could help predict disease trajectory in severe COVID-19 patients

Researchers from the Penn Institute of Immunology discovered three distinct immune responses to the SARS-CoV2 infection that could help predict the trajectory of disease in severe COVID-19 patients and may ultimately inform how to best treat them.

15 Jul 2020

Promising new CAR T cell therapy results in exceptional patient recovery

In a clinical trial evaluating a novel immunotherapy option for cancer treatment, a child with rhabdomyosarcoma, a form of muscle cancer, that had spread to the bone marrow, showed no detectable cancer following treatment with chimeric antigen receptor (CAR) T cells that were engineered to target the HER2 protein on the surface of the cancer cells.

15 Jul 2020

Moderna vaccine induces robust immune response against SARS-CoV-2

The race to develop an effective vaccine against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is on, and one of the potential candidates shows promise in inducing an immune response.

15 Jul 2020

Researchers develop new and promising approach for treatment of lung cancer

A new and promising approach for treatment of lung cancer has been developed by researchers at Lund University. The treatment combines a novel surgical approach with smart nanoparticles to specifically target lung tumors. The new study has been published in the July issue of Advanced Therapeutics.

15 Jul 2020

UC study tests efficacy of immune regulating drug in treating patients with COVID-19 pneumonia

Researchers at the University of Cincinnati are testing a commonly used drug, called sirolimus, to determine its safety and efficacy in treating hospitalized patients with COVID-19 pneumonia in the trial.

15 Jul 2020

Nanotechnology plays major role in COVID-19 vaccine development

From mRNA vaccines entering clinical trials, to peptide-based vaccines and using molecular farming to scale vaccine production, the COVID-19 pandemic is pushing new and emerging nanotechnologies into the frontlines and the headlines.

15 Jul 2020

Anti-inflammatory medication helps fight dangerous immune response in COVID-19 patients

Most patients hospitalized with COVID-19 (coronavirus) pneumonia experienced improvement after receiving a Food and Drug Administration-approved drug normally given for rheumatoid arthritis, according to an observational study at Cedars-Sinai.

15 Jul 2020

Anaplastic large cell lymphoma: Defense mechanism against certain drugs promotes cancer growth

A general problem encountered in cancer therapy is that many patients develop resistance to a drug over the course of treatment.

15 Jul 2020

New trial investigates if prostate cancer drug can be used to treat COVID-19

In a new trial, Swedish researchers will investigate if a medicine normally used to treat prostate cancer can also be used to treat COVID-19 in patients.

15 Jul 2020

10x Genomics launches Chromium Single Cell Immune Profiling v2 product to fight COVID-19

10x Genomics strengthened the research toolkit of scientists around the globe today with the launch of its Chromium Single Cell Immune Profiling v2 product.

15 Jul 2020

Biological anti-tumor mechanism can provide long-term immune response against tumors

Blocking a newly identified "immune memory checkpoint" in immune cells could improve immunotherapy and help prevent cancers from recurring, according to new findings in mice and human samples by researchers at the UPMC Hillman Cancer Center and the University of Pittsburgh School of Medicine.

15 Jul 2020

Antibodies to SARS-CoV-2 disappear within three months

The question is, does this infection confer lasting immunity? A new study published in the journal Clinical Microbiology and Infection in July 2020 appears to show that it does not, with antibodies to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disappearing within three months of infection.

15 Jul 2020

Certain antibodies may cause the dangerous part of COVID-19 disease

A new study out of the Netherlands and published on the preprint server bioRxiv* in July 2020 discusses the commonly observed phenomenon of COVID-19 progression at 1-2 weeks from the onset of the earliest symptoms. This is ascribed to the overactivation of the inflammatory signaling cascade triggered by a hyperactive adaptive immune reaction, commonly called the cytokine storm.

15 Jul 2020

Llama nanobodies block SARS-CoV-2 infection in vitro

Now, a team of scientists at the United Kingdom's Rosalind Franklin Institute may have a surprising solution for the coronavirus pandemic, which has killed more than 574,000 people worldwide.

14 Jul 2020

One in three young adults at a higher risk of severe COVID-19 due to smoking, vaping

Now, a new study shows that about one in three young adults may be at risk of severe COVID-19 due to smoking and vaping habits.

14 Jul 2020

Umbilical cord blood safely and effectively treats children with rare genetic disorders

Researchers at UPMC Children's Hospital of Pittsburgh found that infusing umbilical cord blood - a readily available source of stem cells - safely and effectively treated 44 children born with various non-cancerous genetic disorders, including sickle cell, thalassemia, Hunter syndrome, Krabbe disease, metachromatic leukodystrophy (MLD) and an array of immune deficiencies.

14 Jul 2020

Immune System News and Research

A coronavirus vaccine: Where does it stand?

Study shows how parasitic bacteria cause lesions in the skin and internal organs

Prominent pharmacologist calls for new approach to treat COVID-19

Children with MIS-C have different antibody responses than adults with COVID-19

New immune profiles could help predict disease trajectory in severe COVID-19 patients

Promising new CAR T cell therapy results in exceptional patient recovery

Moderna vaccine induces robust immune response against SARS-CoV-2

Researchers develop new and promising approach for treatment of lung cancer

UC study tests efficacy of immune regulating drug in treating patients with COVID-19 pneumonia

Nanotechnology plays major role in COVID-19 vaccine development

Anti-inflammatory medication helps fight dangerous immune response in COVID-19 patients

Anaplastic large cell lymphoma: Defense mechanism against certain drugs promotes cancer growth

New trial investigates if prostate cancer drug can be used to treat COVID-19

10x Genomics launches Chromium Single Cell Immune Profiling v2 product to fight COVID-19

Biological anti-tumor mechanism can provide long-term immune response against tumors

Antibodies to SARS-CoV-2 disappear within three months

Certain antibodies may cause the dangerous part of COVID-19 disease

Llama nanobodies block SARS-CoV-2 infection in vitro

One in three young adults at a higher risk of severe COVID-19 due to smoking, vaping

Umbilical cord blood safely and effectively treats children with rare genetic disorders

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