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Researchers find evidence of mature heart cell potential in embryonic stem cells

In a new study, UC Davis researchers report the first functional evidence that heart cells derived from human embryonic stem cells exhibit one of the most critical properties of mature adult heart cells, an important biological process called excitation-contraction coupling.

27 Nov 2007

Stem cells train heart following heart attack

Following a heart attack, part of the heart tissue dies. It is still not possible to restore the scar tissue arising as a result of this. The majority of stem cell researchers attempt to make new heart muscle cells from stem cells.

27 Nov 2007

Discovery of gene responsible for statin-induced muscle pain

Statins, the popular class of drugs used to lower cholesterol, are among the most commonly prescribed medications in developed countries.

27 Nov 2007

Researchers outline structure of largest nonvirus particle ever crystallized

Researchers at UCLA's California NanoSystems Institute, the David Geffen School of Medicine at UCLA and the Howard Hughes Medical Institute have modeled the structure of the largest cellular particle ever crystallized, suggesting ways to engineer the particles for drug delivery.

27 Nov 2007

RNA polymerase III mutation disrupts organ growth

The cellular mechanism that turns DNA into all of the thousands of proteins that make up a human body is itself both intricate and interesting.

27 Nov 2007

Positron emission tomography may improve lung cancer diagnosis

Tumor imaging with positron emission tomography (PET) may improve the diagnosis and subsequent treatment of lung cancer patients, according to a review published online November 27 in the Journal of the National Cancer Institute.

27 Nov 2007

Oncolytics Biotech issued new U.S. patent - reovirus for the treatment of neoplasia

Oncolytics Biotech Inc. has announced that it has been granted U.S. Patent 7,300,650 entitled "Reovirus for the Treatment of Neoplasia."

27 Nov 2007

Brain stem-cell therapies more complicated than thought

An MIT research team's latest finding suggests that stem cell therapies for the brain could be much more complicated than previously thought.

27 Nov 2007

Discovery of key acute myeloid leukemia gene

A gene called N-Myc leads a double life in certain white blood cells, helping to trigger a cancer called acute myeloid leukemia (AML) under some conditions while triggering apoptosis, or cell suicide, under other conditions, according to results of a mouse study done by investigators at St. Jude Children's Research Hospital.

27 Nov 2007

Insulin regulates the secretion of the antiaging hormome Klotho

Dr. Carmela Abraham, a professor of biochemistry and medicine at Boston University School of Medicine (BUSM), reports this week in the Proceedings of the National Academy of Sciences new findings on Klotho, an anti-aging gene that is associated with life span extension in rodents and humans.

27 Nov 2007

Cryoablation for bone cancer tumors reduces pain, study shows

Cryoablation, a procedure most commonly associated with destroying kidney and prostate tumors by freezing them, has been shown to offer durable pain relief of cancer that has spread to bone.

27 Nov 2007

Alcohol and tobacco use doesn't boost HPV-related cancer risk

Heavy smoking and drinking are known to cause head and neck cancer. Infection with human papillomavirus type 16 (HPV16), a common strain of the sexually-transmitted HPV virus, is another known risk factor for head and neck cancer, which affects about 500,000 people each year worldwide.

27 Nov 2007

Scientists create mouse resistant to cancer

A mouse resistant to cancer, even highly-aggressive types, has been created by researchers at the University of Kentucky.

27 Nov 2007

Australian stem cell scientist on target to prevent age-related loss of brain function

Stem cell scientists are developing a novel approach to slow or possibly prevent the cognitive decline that typically occurs with advancing age.

27 Nov 2007

Cholera can be controlled with oral vaccines

Endemic cholera, a potentially fatal diarrheal disease found in the world's most impoverished countries, could be effectively controlled by orally vaccinating half of the affected populations once every two years for only pennies per dose, according to new findings by an international team of researchers led by Ira M. Longini Jr., Ph.D., a biostatistician in the Vaccine and Infectious Disease Institute at Fred Hutchinson Cancer Research Center in Seattle. Longini and colleagues will report their findings online Nov. 27 in PLoS Medicine.

27 Nov 2007

Red blood cell transfusions under scrutiny - research reveals potential harm

Bristol scientists have found that red blood cell transfusions given to people having heart surgery could increase the risk of heart attack or stroke.

27 Nov 2007

Pregnant women may be having too many high-tech scans

A new study has found that pregnant women are having more high-tech imaging examinations and are thereby exposing their babies to higher doses of radiation than a decade ago.

27 Nov 2007

Wyeth receives European approval for TORISEL

Wyeth Pharmaceuticals, a division of Wyeth, has announced that the European Commission has approved TORISEL (temsirolimus) for the first-line treatment of patients with advanced renal cell carcinoma (RCC) who have at least three of six prognostic risk factors. TORISEL is the only approved cancer therapy that specifically inhibits the mTOR (mammalian target of rapamycin) kinase, an important regulator of cell proliferation, cell growth and cell survival.

27 Nov 2007

Being overweight bad for bone health

Being overweight is a known risk factor for heart disease, diabetes and a host of other health conditions.

27 Nov 2007

Researchers transfer immune response to myeloma patient

Researchers at the University of Arkansas for Medical Sciences (UAMS) have for the first time transferred an immune response in a healthy individual to a patient with multiple myeloma, a cancer of the bone marrow, showing promise for cancer vaccination.

27 Nov 2007