Antibodies News and Research

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Novel tool can help with analysis of single cell data

CITE-seq (cellular indexing of transcriptomes and epitopes) is an RNA sequencing-based method that simultaneously quantifies cell surface protein and transcriptomic data within a single cell readout.

17 Nov 2023

Immunogenicity of insect-specific Zika virus-vectorized vaccine candidates

The immunogenicity, safety, and effectiveness of ARPV/ZIKV a chimeric insect-specific flavivirus (ISFV)-Zika vaccine.

17 Nov 2023

Lasting heart concerns in kids post-MIS-C: Study urges ongoing cardiac checks

Researchers evaluated the long-term cardiovascular effects in children after treatment for MIS-C, a condition linked to COVID-19. They found that regardless of initial heart injury, most children displayed persistent cardiac abnormalities, underscoring the importance of ongoing cardiac monitoring post-recovery.

16 Nov 2023

B-BiTE modality enhances anti-myeloma effects of clinically available antibodies

Multiple myeloma still appears to be an incurable hematological malignancy. One of the reasons is that myeloma cells can be heterogenous and acquire resistance after anti-myeloma treatment.

16 Nov 2023

Gene splicing determines CD20 levels and response to monoclonal antibody therapy

Immunotherapies that target the CD20 antigen have revolutionized how patients with a variety of blood cancers and hematologic disorders have been treated.

16 Nov 2023

Exploring the dual role of nirmatrelvir and bisphosphonates in COVID-19 treatment and immunity

Review examines nirmatrelvir and bisphosphonates in treating COVID-19, revealing their impact on SARS-CoV-2-specific adaptive immunity and potential to mitigate severe infections, highlighting the need for balanced long-term immunity management.

16 Nov 2023

Senolytics show promise in combating brain aging and COVID-19 neuropathology

Study reveals that senolytics can reduce aging in human brain organoids and mitigate COVID-19 neuropathology, suggesting their potential as a therapeutic strategy against brain aging and coronavirus-related neurological complications.

15 Nov 2023

Stand Up To Cancer unveils new gastroesophageal cancer research teams and awards

Stand Up To Cancer (SU2C) today announced three Research Teams focused on bringing new therapies to clinical trials for the treatment of gastroesophageal cancer (GEC).

15 Nov 2023

Breakthrough study: inhibiting USP30 gene offers hope in treating Parkinson’s disease

Whether USP30 inhibition can serve as a disease-modifying therapy for Parkinson's disease (PD).

15 Nov 2023

Understanding asthma: The surprising influence of gut bacteria

The role of specific gut microbes in asthma.

15 Nov 2023

Study provides insights into longevity of neutralizing antibodies in HIV-1 infection

An international team has for the first time researched the longevity of neutralizing antibodies in HIV-1-infected people.

14 Nov 2023

"Christchurch mutation" can block detrimental effects of Alzheimer’s risk factor

Researchers at Gladstone Institutes have discovered that a rare genetic variant known as the "Christchurch mutation" can block detrimental effects of apolipoprotein E4, the best-established risk factor for the most common form of Alzheimer's disease.

13 Nov 2023

Initial high-risk antibody profile for antiphospholipid syndrome tends to remain high in pediatric patients, study finds

A new study by Hospital for Special Surgery (HSS) investigators has found that an initial high-risk antibody profile for antiphospholipid syndrome (APS) tended to remain high in pediatric patients.

13 Nov 2023

Study sheds light on role of antibodies in vaccine protection against COVID-19 variants

Efforts to contain the Covid-19 pandemic have largely focused on vaccine development and deployment. But how exactly do our immune systems respond to COVID-19 vaccines?

13 Nov 2023

Food allergies may be linked to increased cardiovascular death risk, study finds

Sensitivity to common food allergens such as dairy and peanuts could be an important and previously unappreciated cause of heart disease, new research suggests – and the increased risk for cardiovascular death includes people without obvious food allergies.

13 Nov 2023

Gene therapy's double-edged sword: Breakthrough treatments face manufacturing and efficacy

Research explores the advancements, challenges, and economic implications of gene therapy for various diseases, including inherited blood disorders, malignancies treated with CAR-T cells, and diseases targeted by in vivo AAV vectors. The review highlights the transformative potential of gene therapies while acknowledging the complexities in manufacturing, safety, efficacy, and long-term durability.

12 Nov 2023

High levels of anti-Ro/SSA antibodies linked to fetal heart block in pregnant women

Some individuals with anti-Ro/SSA antibodies (anti–Sjögren's-syndrome–related antigen A autoantibodies, also called anti-Ro antibodies) have autoimmune diseases such as lupus or Sjögren's syndrome, but many have no symptoms.

10 Nov 2023

Data, Design, and Discovery: Andrew Buchanan's Impact on Biologics Innovation

Andrew Buchanan on the Future of Biologics and AI

10 Nov 2023

Revolution by Evolution: Protein Science and its Impact on Drug Discovery

In this interview conducted at SLAS EU 2023 in Brussels, Belgium, we spoke to Mark Abbott, the Managing Director of Peak Proteins, about protein science and its significance in drug discovery.

10 Nov 2023

Mucosal vaccine shows lasting defense against SARS-CoV-2 Omicron in primate study

In this groundbreaking study, researchers developed a mucosal adenoviral-vector vaccine, ChAd-SARS-CoV-2-S, which demonstrated sustained and robust immunity against a challenging Omicron variant in nonhuman primates, indicating a promising direction for durable COVID-19 protection strategies. Unlike traditional intramuscular vaccines, this mucosal vaccine elicited a comprehensive immune response, potentially paving the way for more effective and long-lasting COVID-19 vaccines.

9 Nov 2023

Antibodies News and Research

Novel tool can help with analysis of single cell data

Immunogenicity of insect-specific Zika virus-vectorized vaccine candidates

Lasting heart concerns in kids post-MIS-C: Study urges ongoing cardiac checks

B-BiTE modality enhances anti-myeloma effects of clinically available antibodies

Gene splicing determines CD20 levels and response to monoclonal antibody therapy

Exploring the dual role of nirmatrelvir and bisphosphonates in COVID-19 treatment and immunity

Senolytics show promise in combating brain aging and COVID-19 neuropathology

Stand Up To Cancer unveils new gastroesophageal cancer research teams and awards

Breakthrough study: inhibiting USP30 gene offers hope in treating Parkinson’s disease

Understanding asthma: The surprising influence of gut bacteria

Study provides insights into longevity of neutralizing antibodies in HIV-1 infection

"Christchurch mutation" can block detrimental effects of Alzheimer’s risk factor

Initial high-risk antibody profile for antiphospholipid syndrome tends to remain high in pediatric patients, study finds

Study sheds light on role of antibodies in vaccine protection against COVID-19 variants

Food allergies may be linked to increased cardiovascular death risk, study finds

Gene therapy's double-edged sword: Breakthrough treatments face manufacturing and efficacy

High levels of anti-Ro/SSA antibodies linked to fetal heart block in pregnant women

Data, Design, and Discovery: Andrew Buchanan's Impact on Biologics Innovation

Revolution by Evolution: Protein Science and its Impact on Drug Discovery

Mucosal vaccine shows lasting defense against SARS-CoV-2 Omicron in primate study

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Decoding Cannabis: Differentiating Hemp and Marijuana

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

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