Lipoprotein News and Research

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A lipoprotein is a biochemical assembly that contains both proteins and lipids. The lipids or their derivatives may be covalently or non-covalently bound to the proteins.

New data highlights the gaps in care for children with familial hypercholesterolemia

Children born with a common genetic condition, familial hypercholesterolemia (FH), are at increased risk for atherosclerotic cardiovascular disease (ASCVD) early in life.

18 Nov 2020

Algorithm-driven program improves cholesterol, blood pressure levels

Using a remotely-delivered, algorithm-driven program for disease management, patients experienced significant improvement in cholesterol and blood pressure levels, according to late-breaking research presented today at the American Heart Association's Scientific Sessions 2020.

18 Nov 2020

New program can remotely improve cardiovascular health for broad population of patients

Despite being known risk factors for poor cardiovascular outcomes, blood pressure and low-density lipoprotein (LDL) cholesterol remain undertreated among a large proportion of patients.

17 Nov 2020

Metabolic biomarkers could predict COVID-19 severity

A new study suggests that metabolic biomarkers could possibly predict the severity of COVID-19 in patients.

16 Nov 2020

Individuals with high BMI and LDL cholesterol are at increased risk of COVID-19

A new study led by researchers at Queen Mary University of London uses a novel approach to investigate the effects of cardiovascular risk factors on the risk of COVID-19 infection.

16 Nov 2020

New drug reduces LDL cholesterol in patients with severe hypercholesterolemia

The investigational drug evinacumab reduced low-density lipoprotein (LDL) cholesterol--the so-called "bad" cholesterol--by 50 percent in patients with severe hypercholesterolemia whose condition is resistant to standard treatments, a phase 2 study from the Icahn School of Medicine of Mount Sinai and other global academic sites has found.

16 Nov 2020

UB study reveals the nutritional properties of oil from wild olive trees

The oil from wild olive trees has excellent sensorial, physicochemical and stability characteristics from a nutritional point of view, according to an article published in the journal Antioxidants.

3 Nov 2020

High Throughput Identification and Quantification of Breast Cancer With NMR-Based Metabolomics

Breast cancer is the leading cause of cancer-related death among the female population globally, despite the ever-growing technology of early detection.

From Bruker BioSpin - NMR, EPR and Imaging 30 Oct 2020

Genetic risk scoring of lipoprotein(a) can predict risk of atherosclerotic cardiovascular disease

Elevated levels of a little-known lipoprotein in the blood that may put people at high risk of cardiovascular disease can be as accurately detected by genetic testing as by conventional laboratory measurement, researchers at Massachusetts General Hospital (MGH) have found.

6 Oct 2020

Plasma ACE2 concentration associated with increased risk of major cardiovascular events

A team of scientists at the Population Health Research Institute, Hamilton Health Sciences, and McMaster University, Hamilton, in Ontario, Canada, revealed that increased plasma ACE2 levels in the blood could indicate a higher risk of major cardiovascular events. The study is published in the journal The Lancet.

6 Oct 2020

Vitamin D deficiency during early development can influence metabolic health

Using a zebrafish model, researchers from North Carolina State University have found that vitamin D deficiency during early development can disrupt the metabolic balance between growth and fat accumulation.

29 Sep 2020

Gruthan Bioscience to develop new class of cholesterol-lowering drugs

Gruthan Bioscience, LLC, a Medical University of South Carolina startup based in Charleston, South Carolina, received a Small Business technology Transfer (STTR) award from the National Heart, Blood and Lung Institute in August to take the next step in developing a novel class of cholesterol-lowering drugs to treat familial hypercholesterolemia.

24 Sep 2020

Bioinformatics analysis reveals genes and pathways shared in COVID-19 disease and comorbidities

Using bioinformatics approaches, researchers have identified genes and pathways shared among patients with comorbidities and having severe COVID-19. The research is published on the preprint server bioRxiv in September 2020.

23 Sep 2020

LOX-1-immature neutrophils may help identify COVID-19 patients at risk of thrombosis complication

To predict severe outcome in COVID-19 patients, innate immune cellular signals are analyzed, identifying two novel neutrophil subsets: LOX-1- and CD123-expressing CD10-CD64+. Thromboembolic events correlated with high LOX-1 immature neutrophils – a potential prognostic signature.

17 Sep 2020

Gut Microbiome Health Index distinguishes between healthy and diseased microbiome

What causes some people to develop chronic diseases such as rheumatoid arthritis, cancer and metabolic syndrome while others stay healthy? A major clue could be found in their gut microbiome -- the trillions of microbes living inside the digestive system that regulate various bodily functions.

16 Sep 2020

Keto diet could be beneficial for elderly COVID-19 patients

A recent study by researchers at Yale School of Medicine, New York University Langone Health and Washington University School of Medicine, claims that the ketogenic diet (high fat, low carbohydrate diet) is capable of mitigating clinical outcomes of coronavirus disease 2019 (COVID-19) in elderly people by improving immune-metabolic functions and reducing inflammation. The study is currently available on the bioRxiv* preprint server.

14 Sep 2020

Metabolite signature reveals signs of multi-organ damage in COVID-19 patients

SARS-CoV-2, the virus responsible for COVID-19, can cause a wide range of symptoms, from none at all to severe respiratory stress, multi-organ failure and death.

9 Sep 2020

Study: Generic cholesterol medications save billions of dollars for Medicare

The switch from brand name to generic cholesterol medications that occurred between 2014 and 2018 has saved Medicare billions of dollars, even as the number of people on cholesterol-lowering drugs has increased, UT Southwestern scientists have calculated.

9 Sep 2020

Combinations of lipid-lowering therapies could reduce health risk for European patients

New findings from a large European study of patients in 18 countries, including the UK, show that while many patients are able to reduce their risk through taking statins, those at the highest risk of cardiovascular events may benefit from combinations of lipid-lowering therapies.

28 Aug 2020

Food-based approach reduces LDL cholesterol levels, offers healthcare cost savings

A new study is the first to show a food-based approach using clinically-proven diet interventions to lower cholesterol levels, such as Step One Foods®, provides significant healthcare cost savings.

13 Aug 2020

Lipoprotein News and Research

Further Reading

New data highlights the gaps in care for children with familial hypercholesterolemia

Algorithm-driven program improves cholesterol, blood pressure levels

New program can remotely improve cardiovascular health for broad population of patients

Metabolic biomarkers could predict COVID-19 severity

Individuals with high BMI and LDL cholesterol are at increased risk of COVID-19

New drug reduces LDL cholesterol in patients with severe hypercholesterolemia

UB study reveals the nutritional properties of oil from wild olive trees

High Throughput Identification and Quantification of Breast Cancer With NMR-Based Metabolomics

Genetic risk scoring of lipoprotein(a) can predict risk of atherosclerotic cardiovascular disease

Plasma ACE2 concentration associated with increased risk of major cardiovascular events

Vitamin D deficiency during early development can influence metabolic health

Gruthan Bioscience to develop new class of cholesterol-lowering drugs

Bioinformatics analysis reveals genes and pathways shared in COVID-19 disease and comorbidities

LOX-1-immature neutrophils may help identify COVID-19 patients at risk of thrombosis complication

Gut Microbiome Health Index distinguishes between healthy and diseased microbiome

Keto diet could be beneficial for elderly COVID-19 patients

Metabolite signature reveals signs of multi-organ damage in COVID-19 patients

Study: Generic cholesterol medications save billions of dollars for Medicare

Combinations of lipid-lowering therapies could reduce health risk for European patients

Food-based approach reduces LDL cholesterol levels, offers healthcare cost savings

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