Nephrology News and Research

RSS

Nephrology is a branch of internal medicine and pediatrics dealing with the study of the function and diseases of the kidney.

Recurring glioblastomas with very few mutations are far more vulnerable to immunotherapies

Glioblastoma brain tumors are especially perplexing. Inevitably lethal, the tumors occasionally respond to new immunotherapies after they've grown back, enabling up to 20% of patients to live well beyond predicted survival times.

13 Jan 2021

Poor gut health may adversely affect COVID-19 prognosis

People infected with COVID-19 experience a wide range of symptoms and severities, the most commonly reported including high fevers and respiratory problems.

12 Jan 2021

Endothelial tissue injury significantly contributes to ARDS in COVID-19 patients, finds study

A recent study conducted by scientists from the Yokohama City University, Japan, has revealed that elevated alveolar endothelial injury markers in coronavirus disease 2019 (COVID-19) patients with acute respiratory distress syndrome (ARDS) are the main causative factors for alveolar barrier disruption. In COVID-19 patients with ARDS, endothelial injury persists for a longer time than epithelial injury.

12 Jan 2021

Study finds association between severity of COVID-19 and shorter telomeres

Patients with severe COVID-19 disease have significantly shorter telomeres, according to a study conducted by researchers at the Spanish National Cancer Research Centre in collaboration with the COVID-IFEMA Field Hospital, published in the journal Aging.

11 Jan 2021

Vimentin could be a major co-factor that aids SARS-CoV-2 infection

A recent study has found that extracellular vimentin can bind to SARS-CoV-2 spike protein in vitro, and antibodies against vimentin can decrease virus infectivity by up to 80%. This suggests vimentin could aid the virus’s binding to host cells and help in infection.

11 Jan 2021

SARS-CoV-2-induced innate immune responses may vary with disease severity, finds study

Scientists from Germany and China recently conducted a large meta-analysis using transcriptome data of SARS-CoV-2 to evaluate the routes of viral entry and the characteristics of innate immune responses induced by SARS-CoV-2 infection.

11 Jan 2021

One ambulance ride leads to another when packed hospitals cannot handle non-covid patients

Keely Connolly thought she would be safe once the ambulance arrived at Hutchinson Regional Medical Center in Kansas.

11 Jan 2021

New insights into ferroptosis resistance of cancer cells

Announcing a new publication for BIO Integration journal. In this opinion article the authors Daiyun Xu, Yonghui Lü, Yongxiao Li, Shengbin Li, Zhe Wang and Junqing Wang from Sun Yat-Sen University, Guangzhou, China discuss ferroptosis resistance in cancer.

8 Jan 2021

Study reveals six-month consequences of COVID-19 in patients discharged from hospital

More than three quarters of COVID-19 patients have at least one ongoing symptom six months after initially becoming unwell, according to research published in The Lancet.

8 Jan 2021

Glycylation essential to keep sperm swimming in a straight line, shows study

One essential component of each eukaryotic cell is the cytoskeleton. Microtubules, tiny tubes consisting of a protein called tubulin, are part of this skeleton of cells.

7 Jan 2021

SARS-CoV-2 viral load in saliva may be linked to COVID-19 disease severity

Researchers at Yale University School of Medicine found that SARS-CoV-2 viral loads in saliva are higher for patients with associated risk factors and underlying conditions that lead to severe COVID-19 and death. Thus, saliva viral loads could be used to predict disease severity.

7 Jan 2021

Common gene expression changes at target tissues of four autoimmune diseases found

Autoimmune diseases are diseases of "mistaken identity", where the immune system - which is supposed to protect us against infectious diseases and neoplasias - mistakenly attacks and destroys components of our own body.

7 Jan 2021

Researchers examine the role of Shiga toxin in the immune system

E. coli food poisoning is one of the worst food poisonings, causing bloody diarrhea and kidney damage. But all the carnage might be just an unintended side effect, researchers from UConn Health report in the 27 November issue of Science Immunology.

7 Jan 2021

ACE2 receptor is responsible for the wide host range of SARS-CoV-2

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is thought to have a zoonotic origin, perhaps originating in a bat coronavirus with an unknown intermediate host. It is not only very infectious but has been found to infect a wide range of mammals, including dogs, cats, ferrets, hamsters, and minks, besides non-human primates. This range may be still higher, claims a recent preprint that appeared in January 2021 on the bioRxiv server.

6 Jan 2021

New mathematical model proposes optimal treatment strategies for COVID-19

Getting control of COVID-19 will take more than widespread vaccination; it will also require a better understanding of why the disease causes no apparent symptoms in some people but leads to rapid multi-organ failure and death in others, as well as better insight into what treatments work best and for which patients.

5 Jan 2021

Scientist receives $1.37 million grant to advance metabolomics data

The National Institutes of Health (NIH) has awarded University of Massachusetts Amherst biostatistician Raji Balasubramanian a four-year, $1.37 million grant to advance the analysis of data from metabolomics research.

5 Jan 2021

Biological imbalance found to be the link between gum and kidney disease

An imbalance of the body's oxygen producing free radicals and its antioxidant cells could be the reason why gum disease and chronic kidney disease affect each other, a new study led by the University of Birmingham has found.

5 Jan 2021

Many health plans now must cover full cost of expensive HIV prevention drugs

Ted Howard started taking Truvada a few years ago because he wanted to protect himself against HIV, the virus that causes AIDS. But the daily pill was so pricey he was seriously thinking about giving it up.

5 Jan 2021

Middle-aged adults with comorbidities high-risk category for COVID-19-related mortality in Mexican study

Researchers from Mexico demonstrate how they calculated age-stratified COVID-19 case fatality rates, years of life lost (YLL), and relative risk for 9 comorbidities and 23 comorbidity combinations in a retrospective study.

5 Jan 2021

Research offers clues on why pregnancy may raise risk of organ transplant rejection

A research study at the University of Chicago has found that in pregnancy, while the T cell response to a fetus becomes tolerant to allow for successful pregnancy, the part of the immune system that produces antibodies (known as the humoral response) becomes sensitized, creating memory B cells that can later contribute to the rejection of a transplanted organ.

4 Jan 2021

Nephrology News and Research

Further Reading

Recurring glioblastomas with very few mutations are far more vulnerable to immunotherapies

Poor gut health may adversely affect COVID-19 prognosis

Endothelial tissue injury significantly contributes to ARDS in COVID-19 patients, finds study

Study finds association between severity of COVID-19 and shorter telomeres

Vimentin could be a major co-factor that aids SARS-CoV-2 infection

SARS-CoV-2-induced innate immune responses may vary with disease severity, finds study

One ambulance ride leads to another when packed hospitals cannot handle non-covid patients

New insights into ferroptosis resistance of cancer cells

Study reveals six-month consequences of COVID-19 in patients discharged from hospital

Glycylation essential to keep sperm swimming in a straight line, shows study

SARS-CoV-2 viral load in saliva may be linked to COVID-19 disease severity

Common gene expression changes at target tissues of four autoimmune diseases found

Researchers examine the role of Shiga toxin in the immune system

ACE2 receptor is responsible for the wide host range of SARS-CoV-2

New mathematical model proposes optimal treatment strategies for COVID-19

Scientist receives $1.37 million grant to advance metabolomics data

Biological imbalance found to be the link between gum and kidney disease

Many health plans now must cover full cost of expensive HIV prevention drugs

Middle-aged adults with comorbidities high-risk category for COVID-19-related mortality in Mexican study

Research offers clues on why pregnancy may raise risk of organ transplant rejection

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

Latest News