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Study shows how a non-opioid approach successfully manages women's pain after C-section

For years, women recovering from cesarean section (C-section) deliveries have been given devices that let them, with a button, control the flow of opioid painkillers into their IV line. But as researchers and policymakers push to curb the use of opioids, clinicians are developing new strategies for treating pain after C-sections.

3 May 2022

Study: More than two-thirds of the patients recover from knee replacement without opioids

A retrospective case series study led by Dr. Vinod Dasa, Professor of Clinical Orthopaedics at LSU Health New Orleans School of Medicine, reports that more than two-thirds of the patients who underwent total knee replacement did not need opioids for postoperative pain.

25 Mar 2022

15 medical societies establish seven guiding principles for perioperative treatment of acute pain

The American Society of Anesthesiologists and 14 leading medical specialty organizations established seven guiding principles to better address the perioperative treatment of acute pain in complex surgical patients.

8 Mar 2022

Study reveals the thalamocortical mechanism for nostalgia-induced analgesia

Ever noticed that looking at photos of good times with family or friends diminishes the pain of your headache? Nostalgia has already been shown to be helpful with pain relief, and a new study has now revealed the thalamocortical mechanism for nostalgia-induced analgesia.

28 Feb 2022

Labor neuraxial analgesia associated with reduced risk of severe maternal morbidity

In a study of vaginal births in New York State hospitals, labor neuraxial analgesia – having an epidural or combined spinal and epidural-; was associated with a decreased risk of severe maternal morbidity.

22 Feb 2022

Stomach emptying is slower during labor but faster in women who receive an epidural analgesia

Physician anesthesiologists prefer that laboring women have an empty stomach because of the lower risk for aspiration (inhaling) of food in case general anesthesia for cesarean section becomes necessary.

2 Feb 2022

Researchers explore how opioids may have become so widely abused

Researchers may have uncovered new answers on how to create safer opioids. Design a new opioid to bypass the part of brain that feels pleasure, but retain the analgesic properties, which make opioids one of the most effective pain relievers.

15 Oct 2021

Breakthrough discovery could pave the way for new non-opioid painkillers to treat neuropathic pain

Monash University researchers have made a breakthrough discovery that could pave the way for the development of novel non-opioid painkillers to safely and effectively treat neuropathic pain.

8 Sep 2021

Pain monitoring technology can reduce intraoperative opioid consumption

A new study has shown that effective opioid-sparing anaesthesia with dexmedetomidine can be guided with NOL pain monitoring technology (Medasense, Israel). The study showed that the NOL monitor is able to detect the effect of dexmedetomidine on the patient's pain response and enable administration of less intraoperative opioids.

26 May 2021

New peptides allow cannabis-derived drugs to fight pain in mice without side effects

An international team, led by researchers from Pompeu Fabra University (UPF) in Barcelona, Spain, David Andreu and Rafael Maldonado, has developed a peptides family that allows delta-9-tetrahydrocannabinol (THC), the main component of Cannabis sativa, to fight pain in mice without side effects.

20 May 2021

Researchers harness the body's own ability to block pain

Fentanyl, oxycodone, morphine--these substances are familiar to many as a source of both pain relief and the cause of a painful epidemic of addiction and death.

26 Apr 2021

Study sheds light on the ability of CBD to reduce pain

It's been hailed as a wonder drug and it's certainly creating wonder profits. By some estimates, the Cannabidiol (or CBD) market could be worth $20 billion dollars by 2024.

23 Apr 2021

Study offers new insights on sleep apnea surgery, postoperative respiratory depression

An estimated 50 million people undergo surgery each year in the United States, and a significant proportion of them have undiagnosed or untreated sleep disorders (SD) or sleep-disordered breathing (SDB).

20 Apr 2021

VR offers hope to nerve injury patients experiencing chronic pain

We all feel physical pain in different ways, but people with nerve injuries often have a dysfunctional pain suppression system, making them particularly prone to discomfort.

19 Mar 2021

Study finds link between low dose aspirin and decreased COVID-19 severity, death

George Washington University researchers found low dose aspirin may reduce the need for mechanical ventilation, ICU admission and in-hospital mortality in hospitalized COVID-19 patients.

17 Mar 2021

Study provides detailed insight into neural mechanisms underlying placebo effects

A large proportion of the benefit that a person gets from taking a real drug or receiving a treatment to alleviate pain is due to an individual's mindset, not to the drug itself.

2 Mar 2021

Medicaid expansion in New York associated with reduction in severe maternal morbidity

A study at Columbia University Mailman School of Public Health and Columbia University Irving Medical Center has found that Medicaid expansion in 2014 in New York State was associated with a statistically significant reduction in severe maternal morbidity in low-income women during delivery hospitalizations compared with high-income women.

29 Jan 2021

Multimodal pain regimen minimizes opioid exposure, relieves acute pain in trauma patients

A multimodal pain regimen (MMPR) designed to minimize opioid exposure and relieve acute pain associated with traumatic injury kept patient self-reported pain scores low while also reducing the daily and total amount of opioid drugs given to trauma patients.

21 Jan 2021

Immersive VR can enhance the pain-relieving effectiveness of spinal cord stimulation

For patients receiving spinal cord stimulation (SCS) for chronic pain, integration with an immersive virtual reality (VR) system - allowing patients to see as well as feel the effects of electrical stimulation on a virtual image of their own body - can enhance the pain-relieving effectiveness of SCS, reports a study in PAIN, the official publication of the International Association for the Study of Pain.

23 Dec 2020

Mice study identifies action mechanism of a promising drug against Alzheimer's disease

A study conducted on mice published in the journal Geroscience has identified the action mechanism of a promising compound against Alzheimer's disease, developed by the team of Medical Chemistry and Pharmacology at the University of Barcelona.

9 Dec 2020