Tamiflu (Oseltamivir) News and Research

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Tamiflu (oseltamivir phosphate) is an antiviral drug approved for treatment of uncomplicated influenza A and B in patients 1 year of age or older. It is also approved for prophylaxis (prevention) of influenza in people 13 years or older after household contact or at high risk for exposure during influenza season. Tamiflu is one of a group of anti-influenza drugs called neuraminidase inhibitors that act by blocking the viral enzyme neuraminidase which helps the influenza virus invade cells in the respiratory tract.

Experts warn of dangers of swine flu with almost 10,000 now infected, forecasts 4.9 billion doses needed

The latest figures from the World Health Organisation (WHO) has the worldwide influenza A H1N1 (swine flu) tally fast approaching 10,000 human cases.

19 May 2009

Simple interventions could contain flu spread – focus on children

Although many have touted strategies from travel avoidance to Tamiflu to halt the spread of H1N1 flu or swine flu, a large body of evidence from the Cochrane Library suggests that concentrating on children's hygiene might be the best way to reduce the spread of respiratory illnesses.

12 May 2009

Swine flu could come round again!

The Centres for Disease Protection and Control (CDC) says outbreaks of the new H1N1 swine flu continue to spread across the United States and the swine influenza virus is expected to spread to all 50 states and to cause many infections ranging from mild to severe.

11 May 2009

Africa prepares for possible H1N1 flu outbreak amid concerns about HIV/AIDS, other diseases

African countries are preparing for the possibility that the H1N1 flu virus could expand in the continent, which already is experiencing epidemics of diseases such as HIV/AIDS and malaria, the AP/San Francisco Chronicle reports.

7 May 2009

Swine flu: Action and response from the Cochrane Library

Fears about Swine Flu and notions of the best methods of preventing the spread are sweeping over the world like wild fire, with everyone voicing a different opinion. Is stocking Tamiflu the best option? Do facemasks work? Should we be constantly washing our hands, or never leaving the house?

6 May 2009

Panic buying of flu drug results in rationing

Even though Australia is yet to have had any confirmed cases of influenza A H1N1 (swine flu) there has been such a demand for the anti-viral drug Tamiflu that the drug must now be rationed - it is reported that in the last week 120,000 courses of Tamiflu were sold, compared with about 10,000 courses in a normal flu season and many chemists have run out.

6 May 2009

HIV-positive people worldwide at increased risk of the H1N1 flu

HIV-positive people worldwide are at an increased risk of the H1N1 flu strain, the World Health Organization said on Saturday in guidelines for health workers published on its Web site, Reuters India reports.

5 May 2009

Influenza A (H1N1) swine flu update

As of 16:00 GMT, 3 May 2009, 18 countries have officially reported 900 cases of influenza A (H1N1) infection. Mexico has reported 506 confirmed human cases of infection, including 19 deaths.

4 May 2009

World Health Organisation says wash your hands and sing 'Happy Birthday' twice to avoid swine flu

According to the World Health Organisation (WHO) as of the 2nd May 2009, 16 countries have now officially reported cases of influenza A(H1N1) infection (swine flu).

3 May 2009

Warning on fraudulent 2009 H1N1 influenza products

The U.S. Food and Drug Administration and the Federal Trade Commission are alerting the public to be wary of Internet sites and other promotions for products that claim to diagnose, prevent, mitigate, treat or cure the 2009 H1N1 influenza virus.

3 May 2009

Research model shows best way to deal with a flu pandemic

According to the latest available research, should a global influenza pandemic become a reality, small stockpiles of a secondary flu medication, provided they are used early enough in local outbreaks, could extend the effectiveness of large primary stockpiles of drugs such as Tamiflu.

30 Apr 2009

Sebelius, Obama take action on swine flu

HHS Secretary Kathleen Sebelius on Wednesday held two press conferences and briefed congressional lawmakers on the recent public health emergency involving swine flu, also known as the "2009 H1N1 influenza virus," CQ HealthBeat reports (Reichard, CQ HealthBeat, 4/29).

30 Apr 2009

So far Australia clear of swine flu

According to Queensland's Chief Health Officer, although more cases of suspected swine flu have been reported in the Queensland, to date the state and the nation remain free of the disease.

29 Apr 2009

Flu pandemic long overdue

Here we go again. Just when we thought it was safe to go outside, the threat of another potential flu pandemic raises its head and hysteria builds again. Once again there is talk of quarantine, airport surveillance, travel restrictions and public closures.

29 Apr 2009

Swine flu pandemic threat puts the world on high alert

An outbreak of swine flu in humans has health experts and officials around the world on high alert and there is great concern, as more countries report new cases of the disease, that the world may be on the brink of a pandemic.

27 Apr 2009

Safety of bird flu drug Tamiflu in children questioned

A prominent Japanese researcher reporting on the bird flu drug Tamiflu says the drug may not be safe for children.

20 Apr 2009

Hovione's TwinCaps inhaler in phase III trials for influenza

Hovione has announced that its licensee Daiichi Sankyo has informed that it intends to use Hovione's TwinCaps dry powder inhaler device in the launch of the compound CS-8958, an inhaled long-acting neuraminidase inhibitor active against the influenza virus.

15 Apr 2009

Influenza A's resistance to drug Tamiflu increasing

Influenza A viruses (H1N1 subtype) that are resistant to the drug oseltamivir circulated widely in the U.S. during the 2007-2008 influenza season, with an even higher prevalence of drug resistance during the current 2008-2009 influenza season, according to a study to be published in the March 11 issue of JAMA, the Journal of the American Medical Association.

2 Mar 2009

Scientists identify human monoclonal antibodies effective against bird flu

Researchers at the Dana-Farber Cancer Institute (Dana-Farber), Burnham Institute for Medical Research (Burnham) and the Centers for Disease Control and Prevention (CDC) have reported the identification of human monoclonal antibodies (mAb) that neutralize an unprecedented range of influenza A viruses, including avian influenza A (H5N1) virus, previous pandemic influenza viruses, and some seasonal influenza viruses.

22 Feb 2009

Widespread antiviral drug use can accelerate the evolution of drug resistance in viruses

Influenza's ability to resist the effects of cheap and popular antiviral agents in Asia and Russia should serve as a cautionary tale about U.S. plans to use the antiviral Tamiflu in the event of widespread avian flu infection in humans, scientists say.

7 Jan 2009