Cancer Immunotherapy News and Research

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Research explores relationship between personal history of infectious fever and cancer risk

Recurring patterns in patient accounts suggest the existence of an inverse relationship between personal history of infectious fever and cancer risk, and these patterns are documented throughout decades of medical literature.

17 Aug 2018

Researchers identify way to grow immune cells at large scale for preventing cancer reoccurrence

For the first time, Mount Sinai researchers have identified a way to make large numbers of immune cells that can help prevent cancer reoccurrence, according to a study published in August in Cell Reports.

15 Aug 2018

Patients with chronic lymphocytic leukemia have higher risk of melanoma, shows study

While studying a large group of individuals with chronic lymphocytic leukemia, a Wilmot Cancer Institute scientific team made an important discovery -- these patients had a sizable 600 percent higher risk of melanoma, the most dangerous form of skin cancer.

10 Aug 2018

ETH scientists discover new cancer-specific molecular changes in tumor tissues

A research team led by Gunnar Raetsch, Professor of Biomedical Informatics at ETH Zurich, has evaluated the largest set of genetic data in cancer medicine: The Cancer Genome Atlas in the United States.

9 Aug 2018

Scientists create new tool to precisely control 3D architecture of linkages in drugs

When it comes to certain molecules, shape makes all the difference. The shape of limonene, for instance, a compound produced by citrus fruits, determines whether it tastes like orange juice or turpentine.

7 Aug 2018

Inhibiting a protein could enhance effectiveness of cancer immunotherapies

Researchers at the Bloomberg~Kimmel Institute for Cancer Immunotherapy in the Johns Hopkins Kimmel Cancer Center discovered inhibiting a previously known protein could reduce tumor burdens and enhance the effectiveness of immunotherapy treatments.

31 Jul 2018

Gene linked to hair loss could be exploited to improve cancer immunotherapy

A gene that's associated with an autoimmune form of hair loss could be exploited to improve cancer immunotherapy, suggests a new mouse study by Columbia University Irving Medical Center (CUIMC) researchers.

31 Jul 2018

New research uncovers AEP enzyme's importance to immunity

The importance of the enzyme AEP as a key regulatory of the immune system has been discovered in new research from Newcastle University, UK.

24 Jul 2018

UT Southwestern researchers uncover body's microreactors for innate immunity

A DNA-sensing enzyme forms droplets that act as tiny bioreactors creating molecules to stimulate innate immunity – the body's first response to infection, UT Southwestern researchers report. The work, reported today in the journal Science, could lead to novel treatments for infections, autoimmune disease, and cancer.

9 Jul 2018

Researchers discover immune profile for effective cancer immunotherapy

In a new study published online June 25, 2018 in Nature Medicine, UC San Francisco researchers have identified a key biological pathway in human cancer patients that appears to prime the immune system for a successful response to immunotherapy drugs known as checkpoint inhibitors.

25 Jun 2018

Genetic subset of prostate cancer may benefit from combination checkpoint immunotherapy

Researchers at the Johns Hopkins Kimmel Cancer Center and the Bloomberg~Kimmel Institute for Cancer Immunotherapy released a study investigating the use of combination checkpoint immunotherapy in the treatment of a lethal form of advanced prostate cancer.

25 Jun 2018

Fetal immune cells are fast-acting first responders to microbes in adulthood

Cornell University researchers have discovered there is a division of labor among immune cells that fight invading pathogens in the body.

20 Jun 2018

Monash study reveals why older people have reduced immune responses to cancer therapy

It's called the Silver Tsunami - the increased incidence of cancer with aging, combined with the rapidly aging population means that the Australian health system needs to prepare for an onslaught of cancer diagnoses.

20 Jun 2018

Customising T-cells for cancer immunotherapy

T-cell immunotherapy is revolutionizing cancer treatments. CD8+ T cells are modified to recognize tumor-specific antigens and induce an immune response.

12 Jun 2018

CRISPR-Cas9 technique may raise cancer risk

Therapeutic use of gene editing with the so-called CRISPR-Cas9 technique may inadvertently increase the risk of cancer, according to a new study from Karolinska Institutet, Sweden, and the University of Helsinki, Finland, published in Nature Medicine.

11 Jun 2018

Researchers’ attempt to combine immunotherapy drugs have turned out to be failure

A class of immunotherapy drugs called checkpoint inhibitors has shown great promise against cancer in some patients.

7 Jun 2018

Study finds how colon cancer alters its genes to escape the immune system

A UCLA-led study has found how colon cancer alters its genes during development in order to avoid detection by the immune system, creating a specific genetic imprint in the process.

6 Jun 2018

Scientists identify 'hidden' driver that helps prime the anti-tumor immune response

Like exposing a crime boss whose authority has gone undetected, St. Jude Children's Research Hospital scientists have identified a hidden driver that influences production of the T cells that fight cancer and infections. The study appears today as an advance online publication in the journal Nature.

31 May 2018

Obsidian Therapeutics presents preclinical data on regulated IL12 and IL15 programs

Obsidian Therapeutics, Inc., a biotechnology company dedicated to the development of next-generation cell and gene therapies with pharmacologic operating systems, today announced that the company presented preclinical data on its regulated IL12 and IL15 programs at the Annual Meeting of the American Society of Gene and Cell Therapy in Chicago, IL.

17 May 2018

Lowering blood cholesterol levels could enhance success of T-cell cancer immunotherapy

Cleveland Clinic researchers have demonstrated for the first time that lowering blood cholesterol levels could enhance the success of a specific type of T-cell immunotherapy in fighting cancer.

16 May 2018