Interleukin 5 News and Research

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Ludwig researchers shed more light on key requirement for function of regulatory T cells

A Ludwig Cancer Research study published online September 5th in Nature Immunology illuminates a key requirement for the function of regulatory T cells—immune cells that play a critical role in many biological processes, from suppressing inflammation and deadly autoimmunity to helping tumors evade immune attack.

23 Sep 2016

Fat stem cells can lower risk of diabetes in healthy obese individuals

Obesity is responsible for the deaths of over three million people a year worldwide due to its associated diseases such as diabetes, cancer and cardiovascular disease.

16 Sep 2016

Research findings may pave way for innovative treatments of multiple sclerosis

Researchers at the Research Center for Immunotherapy and the Focus Program Translational Neurosciences of Johannes Gutenberg University Mainz have identified a new mechanism that is involved in the development of autoimmune diseases.

14 Sep 2016

Research findings pave way to effective strategies for treatment of visceral leishmaniasis

A study shows that stimulating the production of interleukin-17A (IL-17A), one of the cytokines released by cells of the immune system, can be an effective strategy for the treatment of visceral leishmaniasis, considered one of the six most important parasitic diseases affecting humans.

25 Aug 2016

Higher nut intake linked to lower levels of inflammatory biomarkers

In a cross-sectional analysis published online today in the American Journal of Clinical Nutrition, researchers looked at the association between habitual nut consumption and inflammatory biomarkers among 5,013 men and women participating in two ongoing prospective cohort studies: the Nurses' Health Study and Health Professionals Follow-up Study.

28 Jul 2016

Scientists discover promising approach to combat life-threatening bacterial infections without antibiotics

Patients suffering from liver cirrhosis often die of life-threatening bacterial infections. In these patients the immune cells are unable to eliminate the bacterial infections.

19 Jul 2016

Researchers identify mechanisms triggering hypergammaglobulinemia

Some autoimmune diseases and persistent infections are characterized by high levels of antibodies in the blood. But what are the causes of this hypergammaglobulinemia? A team headed by INRS's Professor Simona Stäger has successfully identified the mechanisms triggering the phenomenon.

12 Jul 2016

Scientists discover new mechanism by which TNF protects against intracellular pathogens

Tumour necrosis factor (TNF), a messenger substance in the immune system, plays an important role in triggering chronic inflammatory diseases. For this reason, TNF inhibitors are a standard form of treatment for patients with rheumatoid arthritis and certain inflammatory bowel diseases.

11 Jul 2016

Scientists reveal how common symptomless condition can develop into myeloma

Researchers from the University of Birmingham and hospitals across the West Midlands have revealed how a common symptomless condition can develop into the blood cancer myeloma.

11 Jul 2016

MGH researchers discover how obesity increases inflammation, desmoplasia in PDAC patients

Massachusetts General Hospital investigators have discovered the mechanism by which obesity increases inflammation and desmoplasia - an accumulation of connective tissue - in the most common form of pancreatic cancer.

7 Jul 2016

Sleep disturbances, long sleep duration linked to inflammatory illnesses

A new meta-analysis in Biological Psychiatry reports that sleep disturbances and long sleep duration are associated with increases in markers of inflammation.

6 Jul 2016

Study shows how genetic variants control immune cell response to pathogens

A study that is first in its kind and published in Nature Medicine today has looked at how far genetic factors control the immune cell response to pathogens in healthy individuals.

4 Jul 2016

Novel anti-interleukin 1-alpha antibody shows promise in treating advanced colorectal cancer patients

A novel anti-interleukin 1-alpha antibody has shown a significant impact on symptoms, and a high level of safety and tolerability in patients with advanced colorectal cancer, according to phase III data presented at the European Society for Medical Oncology's 18th World Congress of Gastrointestinal Cancer in Barcelona, Spain.

4 Jul 2016

Researcher identifies how Itch protein inhibits colonic inflammation and carcinogenesis

Venuprasad Poojary, PhD, an associate investigator at Baylor Institute for Immunology Research (BIIR), part of Baylor Scott & White Research Institute, reported this week in the journal Nature Immunology the role of a key protein in the regulatory pathway that is involved in limiting colon inflammation and tumor growth.

30 Jun 2016

Why does appetite loss occur during illness? An interview with Prof. Conti and Prof. Francesconi

Appetite, as a word, come from the Latin appetitus, meaning "desire for.” Therefore, appetite can be defined as a pleasurable sensation or the desire to eat. This sensation is coordinated by several brain areas associated with reward processing such amygdala, hippocampus, ventral pallidum, nucleus accumbens and striatum, and others.

28 Jun 2016

Study shows childhood adversities, sleep disturbances interfere with immune system regulation

Adverse childhood experiences and sleep disturbances interfere with immune system regulation, shows research from the University of Eastern Finland.

20 Jun 2016

Legions of immune cells play complex role to destroy Legionella bacteria

Immunologists and microbiologists from the University of Melbourne's Bio21 Molecular Science and Biotechnology Institute and the Peter Doherty Institute for Infection and Immunity - a joint venture between the University of Melbourne and Royal Melbourne Hospital - have led a study that defined a new cell type responsible for turning the attack back on the bacteria.

17 Jun 2016

B lymphocytes can influence psoriasis by regulating cytokine IL-10

"A pathological and very complex autoimmune reaction of the skin": This is the definition doctors and scientists use to describe psoriasis, a disease that affects one to three percent of the population.

8 Jun 2016

Rice study takes deeper look at how inflammation bridges stress and diabetes

A Rice University study has found a link between emotional stress and diabetes, with roots in the brain's ability to control anxiety.

7 Jun 2016

HKUST study suggests innate immune response plays vital role in pathogenesis of AD

Alzheimer's disease (AD) is a devastating condition with no known effective treatment. The disease is characterized by memory loss as well as impaired locomotor ability, reasoning, and judgment. Emerging evidence suggests that the innate immune response plays a major role in the pathogenesis of AD.