Metabolite News and Research

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Metabolites are the intermediates and products of metabolism. The term ''metabolite'' is usually restricted to small molecules.

How SpatialOMx is Delivering New Insights into Disease Research

An interview with Shannon Cornett Ph.D, discussing the use of MALDI-guided spatial molecular analysis for biomarker discovery.

From Bruker Life Sciences Mass Spectrometry 14 Jan 2020

New extract can prevent nephrotoxicity caused by mycotoxin OTA

Today a team of researchers from the Department of Veterinary Medicine and Animal Production of the Federico II University of Naples, in collaboration with the Sbarro Health Research Organization (SHRO), at Temple University in Philadelphia, and the Department of Biotechnology at the University of Siena, Itay, has discovered the effectiveness of a new extract, of natural origin.

7 Jan 2020

New sweat test could help detect a person’s marijuana-use

Forensic chemist Jan Halámek is proving that our own perspiration not only gives away how drunk we are – but if we are high, too.

6 Jan 2020

Researchers offer new perspective on pyrethroid insecticides

In an invited Commentary just published in JAMA Internal Medicine, Columbia Mailman School of Public Health professors Drs. Steven Stellman and Jeanne Mager Stellman offer their perspective on results from a recent study on Pyrethroid, among the most widely used insecticides in the world for public health control of vector-borne illnesses, including West Nile virus.

3 Jan 2020

Research suggests contributory role of 'Asian glow' mutation and alcohol to Alzheimer’s

A new study from Stanford, published on December 12 in the journal Acta Neuropathologica Communications, suggests that an important enzyme that helps break down alcohol in the body is defective in patients with Alzheimer’s disease (AD). Understanding its relationship with alcohol and with genes that predispose to AD could help avert the latter in humans at risk.

12 Dec 2019

Light to moderate lifetime alcohol use raises cancer risk

There have been conflicting reports on health benefits and harm caused by drinking alcohol. A new study from Japanese researchers has proven that taking one drink a day for a decade or two drinks for five years can raise the risk of getting cancers by 5 percent. The study titled “Light to moderate amount of lifetime alcohol consumption and risk of cancer in Japan,” was published in the latest issue of the journal Cancer.

11 Dec 2019

SDSU researchers show cancer-inhibiting potential of flavonoid metabolite

Eating fruits and vegetables is more important than ever.

2 Dec 2019

Leaky gut and space flight – the mechanism revealed

A new study on the effects of simulated microgravity, the condition that astronauts face in space, interferes with the epithelial barrier of the intestine, and the effect persists even after the astronaut returns to a normal environment. The research is published in the journal Scientific Reports.

28 Nov 2019

Space travel can affect intestinal function of astronauts

Bacteria, fungi, and viruses can enter our gut through the food we eat. Fortunately, the epithelial cells that line our intestines serve as a robust barrier to prevent these microorganisms from invading the rest of our bodies.

26 Nov 2019

Key mechanism identified for how antiviral immune responses reprogram liver metabolism

Researchers at the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences identified a key mechanism for how antiviral immune responses reprogram liver metabolism. Their recent study, which was published in the renowned scientific journal Immunity, investigated the communication between inflammation and liver metabolism during chronic viral infection.

26 Nov 2019

Melbourne researchers find how MAIT cells identify and attack foreign invaders

Melbourne researchers have identified what makes a specialized immune cell, known as mucosal-associated invariant T (MAIT), cells boost their numbers and attack foreign invaders at the site of the infection.

15 Nov 2019

Fingerprint sampling could help police distinguish between drug users and non-users

Researchers have developed a tool that can determine whether someone has used heroin, even if they have washed their hands.

11 Nov 2019

Impaired liver function during pregnancy can lead to impaired metabolism and weight gain

Impaired liver function during pregnancy may alter gut bacteria composition and increase the risk of obesity in children, according to results presented at The Society for Endocrinology Annual Conference.

11 Nov 2019

Exercise causes changes to some of the body's metabolites, research finds

New research finds that exercise causes changes to some of the body's metabolites-;small molecules the body produces during metabolism.

7 Nov 2019

Humanizing cell cultures

Today we know the function and metabolism of any mammalian cell depends on its environment. Such cells have long been cultured under conditions consisting of a basal medium with added nutritional serum. This, however, is not an accurate replica of the cell’s environment within the human body.

5 Nov 2019

Single vaping episode of cannabis could yield positive results in urine drug tests

In a study of six adults, Johns Hopkins Medicine researchers report evidence that a single vaping episode of cannabis that is similar in chemical composition to that found in legal hemp products could possibly result in positive results on urine drug screening tests commonly used by many employers and criminal justice or school systems.

From Johns Hopkins Medicine 4 Nov 2019

Researchers discover key mechanism in insulin release by cholesterol metabolite

Insulin which is released by pancreatic beta-cells is the main regulator of blood sugar. Previous and current studies by a research group at Lund University in Sweden have identified around hundred different receptors on the surface of the beta-cells, with a diverse functional impact on the beta-cells.

31 Oct 2019

Metabolite profiling during diagnosis helps identify poor treatment outcomes in ALL

The survival of patients with pediatric acute lymphoblastic leukemia (ALL) has significantly improved in the last several decades. However, novel strategies to identify cases that are likely to respond poorly to treatment are still needed.

24 Oct 2019

UChicago researchers reveal the secret of cancer-related Warburg effect

A new study, led by researchers at the University of Chicago, provides an answer to why cancer cells consume and use nutrients differently than their healthy counterparts and how that difference contributes to their survival and growth.

23 Oct 2019

Performance-enhancing with ... potatoes!

Athletes who are training need to go through grueling endurance tests. One proven strategy to boost their performance during such tests is to eat carbohydrates as race fuels. Now, an interesting study published on October 20, 2019, in the Journal of Applied Physiology reports that athletes in training could get their energy just as well from a mound of pureed potato, rather than spending money on commercial carbohydrate pastes that don’t do the job any better.

21 Oct 2019