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Autobahn Labs collaborates with CSHL to advance science from the lab to clinic

Autobahn Labs, an early-stage drug discovery incubator, today announced a new strategic venture collaboration with Cold Spring Harbor Laboratory.

7 Jun 2021

Experimental monoclonal antibody could be a new weapon against HIV epidemic

An experimental, lab-made antibody can completely prevent nonhuman primates from being infected with the monkey form of HIV, new research published in Nature Communications shows.

7 Jun 2021

Gene therapy may be a safe and effective single-dose treatment for soft bone disease

A preclinical study led by scientists at Sanford Burnham Prebys has established that AAV8-TNAP-D10--a gene therapy that replaces a key enzyme found in bone--may be a safe and effective single-dose treatment for hypophosphatasia (HPP).

7 Jun 2021

Genome-scale CRISPR screens pinpoint promising antiviral compounds against SARS-CoV-2

In a recent research paper currently available on the bioRxiv* preprint server, scientists in the US used genome-scale CRISPR knockout screens to identify factors that promote infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), revealing the potential for broad-spectrum activity across the coronavirus family.

7 Jun 2021

Single BioNTech/Pfizer vaccine dose reduces risk of COVID-19 by nearly 52%, matching clinical trial data

Data gathered from real-world vaccination programs following a single dose of Pfizer vaccine administration shows a reduction of 51.4% in infection risk and effectiveness of 54.4% against symptomatic coronavirus disease 2019 (COVID-19), matching clinical trial results.

7 Jun 2021

Standardizable assay detects T cell responses to SARS-CoV-2 infection

Researchers in the UK have developed a high-throughput standardizable assay that accurately detects T cell responses to infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

6 Jun 2021

Missing antibody molecule may predict disease severity in secondary dengue infection

A first encounter with the dengue virus typically causes very mild symptoms; however, a subsequent infection is a different story.

5 Jun 2021

Shorter treatment regimen found to be effective for treating TB

Tuberculosis (TB) is a deadly infection that occurs in every part of the world. The standard treatment for TB, a six-month multidrug regimen, has not changed in more than 40 years. Patients can find it difficult to complete the lengthy regimen, making it more likely that treatment resistance will develop.

5 Jun 2021

Most Americans may have inadequate understanding of palliative care

The majority of surveyed Americans had an inadequate understanding of palliative care, and frequency of health care utilization was one determinant of knowledge.

5 Jun 2021

Analysis: Mounting pressure on China about Covid ‘lab leak’ could backfire

President Joe Biden has ordered U.S. intelligence agencies to determine whether the Covid virus, or a near ancestor, emerged from a cave, a live-animal market, a farm — or a secretive Chinese laboratory.

4 Jun 2021

Three cases of stroke reported in young adults following covid-19 vaccination

Clots in the arteries (arterial thrombosis) are the most common cause of stroke (ischemic stroke) and have been reported in detail for the first time in young adults who received the Oxford–AstraZeneca covid-19 vaccine in a letter from UK stroke specialists published online in Journal of Neurology Neurosurgery & Psychiatry.

4 Jun 2021

Researchers report how the tobacco and e-cigarette industry capitalized on COVID-19 to promote smoking

Scientific papers suggesting that smokers are less likely to fall ill with covid-19 are being discredited as links to the tobacco industry, reveals an investigation by The BMJ today.

4 Jun 2021

New biomaterial for pancreatic islet transplants does not trigger the body's immune response

A multidisciplinary research team led by Jonathan Lakey, Ph.D., professor of surgery and biomedical engineering at the University of California, Irvine, has developed a biomaterial for pancreatic islet transplants that doesn't trigger the body's immune response.

4 Jun 2021

People who received Pfizer-Biontech vaccine have lower antibody levels targeting the delta variant

Levels of antibodies in the blood of vaccinated people that are able to recognise and fight the new SARS-CoV-2 Delta variant first discovered in India (B.1.617.2) are on average lower than those against previously circulating variants in the UK, according to new laboratory data from the Francis Crick Institute and the National Institute for Health Research (NIHR) UCLH Biomedical Research Centre, published today (Thursday) as a Research letter in The Lancet.

4 Jun 2021

UC San Diego Health offers new immunotherapy treatment for multiple myeloma following FDA approval

Following the Food and Drug Administration's approval, UC San Diego Health is the first designated medical center in San Diego certified to offer a new immunotherapy treatment of multiple myeloma outside of a clinical trial.

3 Jun 2021

New method gives an accurate real-time estimate of epidemic trajectories

A new method to monitor epidemics like COVID-19 gives an accurate real-time estimate of the growth rate of an epidemic by carefully evaluating the relationship between the amount of viruses in infected people's bodies, called the viral load, and how fast the number of cases is increasing or decreasing.

3 Jun 2021

Laboratory News and Research

Autobahn Labs collaborates with CSHL to advance science from the lab to clinic

Experimental monoclonal antibody could be a new weapon against HIV epidemic

Gene therapy may be a safe and effective single-dose treatment for soft bone disease

Genome-scale CRISPR screens pinpoint promising antiviral compounds against SARS-CoV-2

Single BioNTech/Pfizer vaccine dose reduces risk of COVID-19 by nearly 52%, matching clinical trial data

Standardizable assay detects T cell responses to SARS-CoV-2 infection

Missing antibody molecule may predict disease severity in secondary dengue infection

Shorter treatment regimen found to be effective for treating TB

Most Americans may have inadequate understanding of palliative care

Analysis: Mounting pressure on China about Covid ‘lab leak’ could backfire

Three cases of stroke reported in young adults following covid-19 vaccination

Researchers report how the tobacco and e-cigarette industry capitalized on COVID-19 to promote smoking

New biomaterial for pancreatic islet transplants does not trigger the body's immune response

People who received Pfizer-Biontech vaccine have lower antibody levels targeting the delta variant

UC San Diego Health offers new immunotherapy treatment for multiple myeloma following FDA approval

New method gives an accurate real-time estimate of epidemic trajectories

Study aims to improve early screening for adverse childhood experiences by using precision medicine

Lung protein hyperconcentration may be a key factor in predicting COPD risks

Study explores COVID-19 vaccine beliefs and behaviors among college students

Scientists identify many existing drugs with antiviral activity against coronavirus

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