Immune System News and Research

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New weight loss amphetamine could potentially avoid harmful side effects

Despite being officially declared a chronic disease there are very few long-lasting and cost-effective treatments for obesity. Amphetamines are one of the few and they reportedly act in the brain to reduce appetite and increase locomotion or stamina.

13 May 2020

Scientists discover how the iron chelator drives immune system to deal with TB

Although COVID-19 commands the headlines today, tuberculosis (TB) remains the biggest infection killer in the world and multiple drug resistant TB, which does not respond to regular antibiotics, continues to be a major threat to global health.

13 May 2020

Harnessing the formation of natural killer–tumor cell immunological synapse to treat solid cancers

There are immune cells in our bodies that directly destroy infected or cancer cells - they are called natural killer cells. Recently, a POSTECH research team has developed an integrative cancer therapy using adoptive natural killer cell therapy and chemotherapy.

13 May 2020

Researchers urge Ireland government to change recommendations for vitamin D supplements

A new publication from Dr Eamon Laird and Professor Rose Anne Kenny, School of Medicine, and the Irish Longitudinal Study on Ageing (TILDA), in collaboration with Professor Jon Rhodes at University of Liverpool, highlights the association between vitamin D levels and mortality from COVID-19.

13 May 2020

Study shows why older individuals are vulnerable to COVID-19

A group of tiny RNA that should attack the virus causing COVID-19 when it tries to infect the body are diminished with age and chronic health problems, a decrease that likely helps explain why older individuals and those with preexisting medical conditions are vulnerable populations, investigators report.

13 May 2020

Experts review symptoms, diagnosis, and current treatment of COVID-19

The ongoing economic and social impact of the pandemic is staggering, but despite a daily flood of news on the disease, few laypeople know that paradoxically, COVID-19 mostly kills through an overreaction of the immune system, whose function is precisely to fight infections.

13 May 2020

Vaccine design can face specific challenges, say researchers

The goal of a vaccine is to trigger a response that safely protects against an infection and/or the burden of disease.

13 May 2020

Study explores whether senicapoc drug can mitigate lung damage in COVID-19 patients

Scientists around the globe are working to identify approved and investigational drugs that can be repurposed to treat COVID-19.

13 May 2020

New study to evaluate drug combination treatment for uveitis

Two in 10,000 people are at risk of serious sight loss from a form of eye inflammation known as uveitis. A new clinical research study, led by the University of Bristol and University Hospitals Bristol and Weston NHS Foundation Trust (UHBW), will evaluate a drug combination treatment for the eye disease thanks to funding of £2.5 million by the National Institute for Health Research (NIHR).

13 May 2020

Researchers launch clinical trial to test the efficacy of antidepressant against COVID-19

An antidepressant medication is being tested as a potential treatment for COVID-19 after University of Virginia School of Medicine researchers determined it may prevent dangerous overreactions by the immune system.

13 May 2020

Research examines molecules derived from ticks as potential COVID-19 treatment option

UK-based biotechnology firm ILC Therapeutics is working alongside the University of Oxford to examine the use of Evasins – molecules derived from ticks – as a potential COVID-19 treatment option for patients whose lungs are badly damaged by the virus and face a critical juncture in recovery.

13 May 2020

Analysis of single-cell data indicates that SARS-Cov-2 targets many cell types

Before it can sicken people, the new coronavirus must first sneak into their cells. But not any cell will do. The virus can enter only those with a certain combination of molecules on their surfaces.

13 May 2020

Innovative approach turns 'cold' tumors 'hot' to improve cancer immunotherapy

Scientists from the Tumor Immunotherapy and Microenvironment research group led by Dr Bassam Janji at the Luxembourg Institute of Health Department of Oncology, and the Swedish pharma company Sprint Bioscience published the results of an innovative approach that turns “cold” tumors “hot”. “Cold”, immune-desert tumors are classically immunotherapy-resistant.

13 May 2020

Could JAK blockers help treat COVID-19?

A new study published in the journal Science Immunology in May 2020 reports that compounds that safely inhibit the JAK protein could be useful in treating COVID-19.

12 May 2020

Platelets can intensify inflammatory processes, study shows

Platelets not only play a key role in blood clotting, but can also significantly intensify inflammatory processes.

12 May 2020

Fasting-mimicking diet plus vitamin C could be effective at treating some cancer types

Scientists from USC and the IFOM Cancer Institute in Milan have found that a fasting-mimicking diet could be more effective at treating some types of cancer when combined with vitamin C.

12 May 2020

New discovery may contribute to early identification of aggressive breast tumors

Immune system cells in the blood of breast cancer patients undergo alterations early in the disease course, according to a study published in the journal Clinical & Translational Immunology.

12 May 2020

Clinical trial to test the efficacy of defibrotide medicine for reducing COVID-19 death rate

The Neurosciences Institute, mixed centre of the Spanish National Research Council and the Miguel Hernández University of Elche, have collaborated on the first clinical trial conducted in the world to test whether the defibrotide medicine, which has already been authorized to treat a severe obstruction of the hepatic sinusoidal veins of people who have undergone a bone marrow transplant, can be used as therapy against COVID-19.

12 May 2020

Neovii and Tel Aviv University partner to develop novel COVID-19 vaccine

Ramot, Tel Aviv University's technology transfer company, and Neovii, a Swiss-based biopharmaceutical company and a member of Israel-based Neopharm Group, announced today that they have signed a research and license agreement to develop a novel and potentially life-saving COVID-19 vaccine.

12 May 2020

Clinical trial to evaluate two-drug immunotherapy combination in cancer patients with COVID-19

A unique two-drug immunotherapy combination first evaluated at Roswell Park Comprehensive Cancer Center as an approach for treating some cancers will soon be available to cancer patients with COVID-19 through a clinical trial at Roswell Park.

12 May 2020

Immune System News and Research

New weight loss amphetamine could potentially avoid harmful side effects

Scientists discover how the iron chelator drives immune system to deal with TB

Harnessing the formation of natural killer–tumor cell immunological synapse to treat solid cancers

Researchers urge Ireland government to change recommendations for vitamin D supplements

Study shows why older individuals are vulnerable to COVID-19

Experts review symptoms, diagnosis, and current treatment of COVID-19

Vaccine design can face specific challenges, say researchers

Study explores whether senicapoc drug can mitigate lung damage in COVID-19 patients

New study to evaluate drug combination treatment for uveitis

Researchers launch clinical trial to test the efficacy of antidepressant against COVID-19

Research examines molecules derived from ticks as potential COVID-19 treatment option

Analysis of single-cell data indicates that SARS-Cov-2 targets many cell types

Innovative approach turns 'cold' tumors 'hot' to improve cancer immunotherapy

Could JAK blockers help treat COVID-19?

Platelets can intensify inflammatory processes, study shows

Fasting-mimicking diet plus vitamin C could be effective at treating some cancer types

New discovery may contribute to early identification of aggressive breast tumors

Clinical trial to test the efficacy of defibrotide medicine for reducing COVID-19 death rate

Neovii and Tel Aviv University partner to develop novel COVID-19 vaccine

Clinical trial to evaluate two-drug immunotherapy combination in cancer patients with COVID-19

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