Cell Proliferation News and Research

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Free fatty acids in the blood linked with elevated risk of breast cancer in obese women

Scientists at the University of Illinois have found that free fatty acids in the blood appear to boost proliferation and growth of breast cancer cells. The finding could help explain obese women's elevated risk of developing breast cancer after menopause.

14 Mar 2019

Study: Cancer stem-like cells are maintained by MTHFD2 mitochondrial metabolic enzyme

An increase in the incidence and mortality rate of cancer has been noted worldwide, especially for lung cancer.

22 Feb 2019

Customizing the Cellular Microenvironment to Improve Physiological Relevance

An interview with Marie-Charlotte Manus, discussing a new technology called PRIMO that improves the physiological relevance of cells in culture.

From Alveole 18 Feb 2019

Over-abundance of energy to cells could increase cancer risk

It's well-known that obesity, diabetes and chronic inflammation are major risk factors for cancer. But just how cancer evolves in people with these diseases -- and why a healthy diet and exercising regularly can help prevent it -- is poorly understood.

12 Feb 2019

Cannabinoid receptor type 1 appears to be potential target to treat Down syndrome

A study by the Neuropharmacology Laboratory-NeuroPhar of the Department of Experimental and Health Sciences at UPF reveals the involvement of the endocannabinoid system in cognitive disorders in mouse models of Down syndrome.

7 Feb 2019

Study of spermatogonial stem cells opens path for new strategies to treat male infertility

The production of sperm -- otherwise known as spermatogenesis -- generates more than 1,000 sperm per second in normal males.

6 Feb 2019

Protein CDK6 appears to be key factor in influencing development of MPN

MPNs are a group of rare, malignant diseases of the bone marrow involving the production of an excess of red blood cells, white blood cells and/or platelets.

6 Feb 2019

Research using fission yeast reveals anticancer mechanism

Much like shoelaces or dangly necklaces, DNA strands can tangle up in unruly knots. Specialized enzymes keep DNA organized when cells divide, so the cells split smoothly and don't get stuck. But in tumor cells, this failsafe allows cancer to spread.

5 Feb 2019

Mapping mutations in esophageal cancer could improve treatment options

Mutations that cause oesophageal adenocarcinoma have been mapped in unprecedented detail - unveiling that more than half could be targeted by drugs currently in trials for other cancer types.

4 Feb 2019

Two major forms of CD44 have distinct biological functions in breast cancer, shows study

One of the main obstacles to successfully treating breast cancer is the cells' ability to change in ways that make them resistant to treatment.

29 Jan 2019

New approach identifies epigenetic changes in leukemia cells for patients undergoing ibrutinib treatment

Many new anti-cancer drugs inhibit proteins that are essential for the proliferation of cancer cells. One example is ibrutinib, an innovative therapy for chronic lymphocytic leukemia first approved in 2014.

29 Jan 2019

Researchers identify marker protein that offers both diagnostic and therapeutic function

Of all gastrointestinal cancers, pancreatic cancer is one of the most aggressive. Because of this, it has a very low 5-year survival rate of just 5% and a median survival time below 6 months. Additionally, treatment is difficult, with only surgery shown to provide a cure. However, the vast majority of patients have tumors that cannot be removed surgically or their cancer is too advanced or spread too far to be treatable.

24 Jan 2019

Study uncovers a protein involved in lung cancer treatment resistance

Lung cancer remains a major cause of mortality across the globe, although we are gaining a deeper understanding of the genetic background behind this disease, including the mutations that promote it.

10 Jan 2019

New mechanism of gene regulation involved in tumor progression discovered

Genes contain all the information needed for the functioning of cells, tissues, and organs in our body. Gene expression, meaning when and how are the genes being read and executed, is thoroughly regulated like an assembly line with several things happening one after another.

9 Jan 2019

Drug combination has added benefit for patients with melanoma

The German Institute for Quality and Efficiency in Health Care investigated whether the drug combinations of dabrafenib plus trametinib and of encorafenib plus binimetinib have an added benefit in comparison with the appropriate comparator therapies for patients with melanoma.

9 Jan 2019

Cell Proliferation News and Research

Free fatty acids in the blood linked with elevated risk of breast cancer in obese women

Study: Cancer stem-like cells are maintained by MTHFD2 mitochondrial metabolic enzyme

Customizing the Cellular Microenvironment to Improve Physiological Relevance

Over-abundance of energy to cells could increase cancer risk

Cannabinoid receptor type 1 appears to be potential target to treat Down syndrome

Study of spermatogonial stem cells opens path for new strategies to treat male infertility

Protein CDK6 appears to be key factor in influencing development of MPN

Research using fission yeast reveals anticancer mechanism

Mapping mutations in esophageal cancer could improve treatment options

Two major forms of CD44 have distinct biological functions in breast cancer, shows study

New approach identifies epigenetic changes in leukemia cells for patients undergoing ibrutinib treatment

Researchers identify marker protein that offers both diagnostic and therapeutic function

Study uncovers a protein involved in lung cancer treatment resistance

New mechanism of gene regulation involved in tumor progression discovered

Drug combination has added benefit for patients with melanoma

Johns Hopkins researchers identify new marker for early detection of colorectal cancers

Study elucidates how essential amino acid in humans acts as growth signal for cells

Study explains effects of aging on endothelial health and vascular regenerative capacity

Weakened metabolism of immune T cells may account for serious complications in elderly

Unraveling the complexity of cancer biology can prompt new avenues for drug development

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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