Neurological Disease News and Research

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Henry Ford researchers propose new treatment strategy for stroke, other neurological disorders

Medicine should reconsider how it treats stroke and other neurological disorders, focusing on the intrinsic abilities of the brain and nervous system to heal themselves rather than the "modest" benefits of clot-busting drugs and other neuroprotective treatments.

3 Mar 2015

New genetic discovery may lead to effective treatments for Huntington's disease

A new genetic discovery in the field of Huntington's disease (HD) could mean a more effective way in determining severity of this neurological disease when using specific treatments. This study may provide insight for treatments that would be effective in slowing down or postponing the death of neurons for people who carry the HD gene mutation, but who do not yet show symptoms of the disease.

2 Mar 2015

CAMH scientists discover potential new approach to treat multiple sclerosis

Scientists at the Centre for Addiction and Mental Health have discovered a promising new approach to treat multiple sclerosis (MS). In a new study, they've identified a previously unknown change in the spinal cord related to MS, and a way to alter this change to reduce the nerve cell damage that occurs with the disease.

18 Feb 2015

Research: Complex nerve circuits first evolved in common ancestor of humans and cnidarians

New research shows that a burst of evolutionary innovation in the genes responsible for electrical communication among nerve cells in our brains occurred over 600 million years ago in a common ancestor of humans and the sea anemone.

17 Feb 2015

Novartis receives priority review status from FDA for heart failure medicine LCZ696

Novartis announced today that the US Food and Drug Administration has granted priority review for LCZ696, an investigational medicine for the treatment of heart failure with reduced ejection fraction (HFrEF). The designation is intended to accelerate the review of therapies that offer a significant improvement in the safety or effectiveness of the treatment, prevention or diagnosis of a serious condition.

16 Feb 2015

'Mad Cow' discovery points to possible neuron killing mechanism behind alzheimer’s and parkinson’s diseases

The new study, published recently in the journal Brain, revealed the mechanism of toxicity of a misfolded form of the protein that underlies prion diseases, such as bovine spongiform encephalopathy (“mad cow disease”) and its human equivalent, Creutzfeldt-Jakob disease.

13 Feb 2015

Epigem contribute to PhD research into Multiple Sclerosis

Epigem, a high-tech British micro engineering company, is supporting research into Multiple Sclerosis (MS) with a new PhD programme to create a novel drug screening platform. This will accelerate the production of MS models and pre-clinical drug development, in order to understand better the disease process and its periods of remission.

10 Feb 2015

Isis receives $5 million from Biogen Idec to develop drugs for neurological disorders

Isis Pharmaceuticals, Inc. announced today it has earned a $5 million milestone payment from Biogen Idec associated with the validation of an undisclosed target to treat a neurological disorder under its broad strategic collaboration with Biogen Idec to develop drugs to treat patients with neurological disorders.

10 Feb 2015

Three groups of researchers receive BRAIN Initiative funding to improve artificial limb technology

Three groups of researchers who have received support from the National Institutes of Health will obtain funding from the President's BRAIN Initiative to improve artificial limb technology. The new awards will be funded and administered by the Defense Advanced Research Projects Agency and will build on the fundamental discoveries that were made possible by NIH support.

10 Feb 2015

Study provides further evidence of cerebellum's role in higher cognitive functions

Grasping an object involves a complex network of brain functions. First, visual cues are processed in specialized areas of the brain. Then, other areas of the brain use these signals to control the hands to reach for and manipulate the desired object.

9 Feb 2015

Two researchers receive Pioneer Award from Human Gene Therapy

Recognized for their pioneering work in the development of gene transfer technology using retroviral vectors to deliver therapeutic genes into cells, Richard C. Mulligan, PhD, Director of the Harvard Gene Therapy Initiative, Harvard Institutes of Medicine, Boston, MA, and A. Dusty Miller, PhD, Fred Hutchinson Cancer Research Center, Seattle, WA, received the Pioneer Award from Human Gene Therapy, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

9 Feb 2015

Exploring better treatment for adolescent idiopathic scoliosis

Adolescent idiopathic scoliosis (AIS) affects 2-3% of children aged between 10 and 16. It is more common in girls than in boys (with a ratio of 10-1). Besides the obvious physical signs derived from the visible spinal deformity, AIS can cause psychological and emotional problems (low self-esteem, poor self-image body, etc.) that significantly reduces patients' quality of life.

31 Jan 2015

Rare respiratory virus could be linked to severe neurological illness in children

A cluster of children from Colorado in the USA have been treated for muscle weakness or paralysis that may be connected to a nationwide outbreak of a usually rare respiratory virus called enterovirus D68 (EV-D68), one of more than 100 non-polio enteroviruses.

31 Jan 2015

Reducing A2A adenosine receptor levels prevents memory impairments in Alzheimer's mouse model

A study by scientists from the Gladstone Institutes shows that decreasing the number of A2A adenosine receptors in a particular type of brain cells called astrocytes improved memory in healthy mice. What's more, reducing receptor levels also prevented memory impairments in a mouse model of Alzheimer's disease.

28 Jan 2015

Researchers test pocket stimulator on patients with Parkinson's disease

Parkinson's disease is a slowly degenerative neurological disease that is expressed as impaired motor control, tremors, stiffness and, in later stages, problems with balance.

21 Jan 2015

AMRI awarded NIH contract for drug development services

AMRI today announced it received a 10-year federal contract award from the National Institutes of Health for drug development and manufacturing services. This NIH/National Institute of Neurological Disorders and Stroke award will support NIH's Drug Manufacturing and Formulation Program (DMFP), which is a component of the Blueprint Neurotherapeutics Network (BPN).

19 Jan 2015

Individualized, patient-centered care needed to treat and monitor people with chronic pain

An independent panel convened by the National Institutes of Health concluded that individualized, patient-centered care is needed to treat and monitor the estimated 100 million Americans living with chronic pain. To achieve this aim, the panel recommends more research and development around the evidence-based, multidisciplinary approaches needed to balance patient perspectives, desired outcomes, and safety.

14 Jan 2015

Two leading biotechnology companies collaborate to gain further understanding of Parkinson’s disease

This week 23andMe (a genetic testing company) and Genentech (medical research company of the Roche Group) agreed a collaboration to undertake whole genome sequencing for 3,000 patients with Parkinson’s disease. The genetic information will be collected by 23andMe and used by Genentech to identify new therapeutic targets for treating Parkinson’s disease.

9 Jan 2015

Neurological testing accessibility and affordability: an interview with Dr Joseph Higgins

Neurological disorders with genetic causes can be very difficult to diagnose without reliable, clinically relevant tests tailored to specific phenotypes.

From Quest Diagnostics 5 Jan 2015

Penn, UGA scientists awarded new contract to develop genome database for microbial pathogens

At the turn of the millennium, the cost to sequence a single human genome exceeded $50 million, and the process took a decade to complete. Microbes have genomes, too, and the first reference genome for a malaria parasite was completed in 2002 at a cost of roughly $15 million. But today researchers can sequence a genome in a single afternoon for just a few thousand dollars. Related technologies make it possible to capture information about all genes in the genome, in all tissues, from multiple individuals.

18 Dec 2014

Neurological Disease News and Research

Henry Ford researchers propose new treatment strategy for stroke, other neurological disorders

New genetic discovery may lead to effective treatments for Huntington's disease

CAMH scientists discover potential new approach to treat multiple sclerosis

Research: Complex nerve circuits first evolved in common ancestor of humans and cnidarians

Novartis receives priority review status from FDA for heart failure medicine LCZ696

'Mad Cow' discovery points to possible neuron killing mechanism behind alzheimer’s and parkinson’s diseases

Epigem contribute to PhD research into Multiple Sclerosis

Isis receives $5 million from Biogen Idec to develop drugs for neurological disorders

Three groups of researchers receive BRAIN Initiative funding to improve artificial limb technology

Study provides further evidence of cerebellum's role in higher cognitive functions

Two researchers receive Pioneer Award from Human Gene Therapy

Exploring better treatment for adolescent idiopathic scoliosis

Rare respiratory virus could be linked to severe neurological illness in children

Reducing A2A adenosine receptor levels prevents memory impairments in Alzheimer's mouse model

Researchers test pocket stimulator on patients with Parkinson's disease

AMRI awarded NIH contract for drug development services

Individualized, patient-centered care needed to treat and monitor people with chronic pain

Two leading biotechnology companies collaborate to gain further understanding of Parkinson’s disease

Neurological testing accessibility and affordability: an interview with Dr Joseph Higgins

Penn, UGA scientists awarded new contract to develop genome database for microbial pathogens

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