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Wyss Institute licenses nasal swab collection technology to Massachusetts-based startup

The Wyss Institute for Biologically Inspired Engineering at Harvard University and Harvard Medical School (HMS) and the Massachusetts-based startup Rhinostics announced today that the University's sample collection swab and high-throughput automation technologies have been licensed to Rhinostics.

4 May 2021

Proteomic and transcriptomic profiling provide a full picture of aging process in the kidneys

Studying protein changes in the kidneys as we age, as well as the transcription of genes into proteins, helps provide a full picture of the age-related processes that take place in these organs, says a study in mice published today in eLife.

4 May 2021

Occupational exposure to low levels of blast linked with neurotrauma biomarker levels

Scientists at the Walter Reed Army Institute for Research demonstrated that biomarkers associated with traumatic brain injury were elevated among law enforcement and military personnel, particularly in active duty participants with longer duration of service.

4 May 2021

Can SARS-CoV-2’s impairment of endothelium cause vascular disease?

The study, published in the journal Circulation Research, suggests that COVID-19 is not only a respiratory disease but also a vascular disease. It highlights how the virus attacks the vascular system, causing endothelial impairment.

4 May 2021

Four-part small-molecule cocktail can prevent cellular stress

Researchers at the National Institutes of Health (NIH) have devised a four-part small-molecule cocktail that can protect stem cells called induced pluripotent stem cells (iPSCs) from stress and maintain normal stem cell structure and function.

4 May 2021

Conspiracies beliefs about COVID-19 increased among users of conservative and social media

Belief in conspiracies about the COVID-19 pandemic increased through the early months of the U.S. outbreak among people who reported being heavy users of conservative and social media, a study by Annenberg Public Policy Center (APPC) researchers has found.

4 May 2021

Rapid and sensitive SARS-CoV-2 detection from saliva using CRISPR

In a paper recently uploaded to the preprint server medRxiv by Edward Málaga Trillo et al. (April 29th, 2021), these methods are tested in combination with CRISPR-Cas detection in the field, demonstrating a sensitivity and specificity of 93.8% and 99%, respectively.

4 May 2021

New computational tool helps screen molecules for their potential COVID-fighting properties

A year into the COVID-19 pandemic, mass vaccinations have begun to raise the tantalizing prospect of herd immunity that eventually curtails or halts the spread of SARS-CoV-2.

4 May 2021

Researchers discover new way to improve the subcutaneous administration of mRNA

If not before, then certainly since the first messenger RNA (mRNA) vaccines to combat the SARS CoV2 virus were approved in Germany, mRNA has become a recognized term even outside scientific circles.

4 May 2021

New medical technology helps stop traumatic bleeding on the battlefield

A new medical technology stops traumatic bleeding without requiring wound compression for Soldiers on the battlefield. Hemorrhaging is a leading cause of preventable death for Soldiers in combat.

3 May 2021

Social cognition may exert a central role in the daily lives of MS patients

An international team of multiple sclerosis (MS) researchers showed that longitudinal changes in social cognition are associated with psychological outcomes of daily living, suggesting that social cognition may exert a central role in people with MS.

3 May 2021

Designing effective multidrug-resistant-TB treatments based on DNA sequencing

Globally, tuberculosis is the most common bacterial infectious disease leading to death. The pathogen causing tuberculosis, Mycobacterium tuberculosis, has a number of peculiarities. One is that it is growing very slowly.

3 May 2021

SARS-CoV-2 antibodies are detectable up to a year after infection, finds study

A team of scientists from the United States has recently investigated the robustness and durability of anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies in coronavirus disease 2019 (COVID-19) patients. Their findings reveal that COVID-19 patients exhibit a strong anti-SARS-CoV-2 antibody response for up to 1 year and that the robustness of antibody response depends on the patient’s age and disease severity.

3 May 2021

Interdisciplinary project explores the phenomenon of so-called “superspreaders”

Scientists from the Departments of Physics, Biomedical Sciences and Process Engineering at Otto von Guericke University Magdeburg are in the process of analyzing the emergence and spread of infectious air bubbles in our breath, known as aerosols, using tissue cultivations and artificially-produced, virus-filled suspended particles.

3 May 2021

Study reveals new broadly neutralizing and protective antibody against coronaviruses

In the setting of potentially reduced vaccine efficacy against coronavirus disease (COVID-19) due to emerging viral variants, the deployment of effective treatments based on monoclonal antibodies may be an additional strategy to help control the pandemic. A new study by US researchers, currently available on the bioRxiv* preprint server, describes the action of a specific antibody known as DH1047.

3 May 2021

Previously infected vaccinees broadly neutralize SARS-CoV-2 variants of concern

Researchers in the United States have conducted a study demonstrating the effectiveness of first-generation vaccines at protecting against variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in individuals who have previously been infected with the virus.

2 May 2021

Antiviral T cells safe, effective as off-the-shelf therapy for painful complication after stem cell transplants

A Phase II trial led by researchers at The University of Texas MD Anderson Cancer Center found that BK virus (BKV)-specific T cells from healthy donors were safe and effective as an off-the-shelf therapy for BKV-associated hemorrhagic cystitis (BKV-HC), a painful complication common after allogeneic stem cell transplants for patients with leukemia or lymphoma.

30 Apr 2021

New technology enables faster and more accurate tracing of COVID-19 and other viruses

Jeremy Edwards, director of the Computational Genomics and Technology (CGaT) Laboratory at The University of New Mexico, and his colleagues at Centrillion Technologies in Palo Alto, Calif. and West Virginia University, have developed a chip that provides a simpler and more rapid method of genome sequencing for viruses like COVID-19.

30 Apr 2021

Scientists develop an ultrasonic imaging system to visualize cell abnormalities in 3D

Scientists at the University of Nottingham have developed an ultrasonic imaging system, which can be deployed on the tip of a hair-thin optical fiber, and will be insertable into the human body to visualize cell abnormalities in 3D.

30 Apr 2021

Furin cleavage site crucial in SARS-CoV-2 for viral transmission in ferrets, finds study

Researchers based at Imperial College London, UK, have recently highlighted the effects of these deleterious CS mutations through a ferret animal model, demonstrating that furin cleavage sites are a necessary component in the virus’ ability to replicate.

30 Apr 2021

Laboratory News and Research

Wyss Institute licenses nasal swab collection technology to Massachusetts-based startup

Proteomic and transcriptomic profiling provide a full picture of aging process in the kidneys

Occupational exposure to low levels of blast linked with neurotrauma biomarker levels

Can SARS-CoV-2’s impairment of endothelium cause vascular disease?

Four-part small-molecule cocktail can prevent cellular stress

Conspiracies beliefs about COVID-19 increased among users of conservative and social media

Rapid and sensitive SARS-CoV-2 detection from saliva using CRISPR

New computational tool helps screen molecules for their potential COVID-fighting properties

Researchers discover new way to improve the subcutaneous administration of mRNA

New medical technology helps stop traumatic bleeding on the battlefield

Social cognition may exert a central role in the daily lives of MS patients

Designing effective multidrug-resistant-TB treatments based on DNA sequencing

SARS-CoV-2 antibodies are detectable up to a year after infection, finds study

Interdisciplinary project explores the phenomenon of so-called “superspreaders”

Study reveals new broadly neutralizing and protective antibody against coronaviruses

Previously infected vaccinees broadly neutralize SARS-CoV-2 variants of concern

Antiviral T cells safe, effective as off-the-shelf therapy for painful complication after stem cell transplants

New technology enables faster and more accurate tracing of COVID-19 and other viruses

Scientists develop an ultrasonic imaging system to visualize cell abnormalities in 3D

Furin cleavage site crucial in SARS-CoV-2 for viral transmission in ferrets, finds study

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