Immune System News and Research

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Johns Hopkins experts create clinical guidebook for convalescent plasma therapy

A team of Johns Hopkins experts has created a clinical guidebook to help hospitals and medical centers rapidly scale up their ability to deliver so-called convalescent plasma therapy, which leverages immune system components found in the plasma portion of blood from people who have recovered from COVID-19 illness.

14 Apr 2020

Predicting the evolution of genetic mutations

Biologists have developed an algorithm able to predict how genetic mutations can make critical proteins change with evolution.

14 Apr 2020

Tumors commandeer cell death pathway to avoid immune system attack after radiation

Cancer cells avoid an immune system attack after radiation by commandeering a cell signaling pathway that helps dying cells avoid triggering an immune response, a new study led by UTSW scientists suggests.

13 Apr 2020

UTSW researchers show how vulnerable cells armor themselves against infection

Cells in some of the body's most vulnerable entry routes to bacterial infection buffer themselves when the immune system detects danger by reorganizing the cholesterol on their surfaces, a new study led by UTSW scientists suggests.

13 Apr 2020

CRISPR may help in kidney-transplants by detecting viruses

An exciting new study published in the journal Nature Biomedical Engineering in April 2020 reports excellent results with a new test for two common viruses that infect kidney transplant patients. The levels of these viruses shoot up during the acute phase of rejection.

13 Apr 2020

How does COVID-19 attack the body?

The coronavirus disease (COVID-19) attacks the lungs, leading to pneumonia, and eventually, a cascade of serious complications. But how does COVID-19 kill? Is it the virus itself or the result of the person’s immune system response?

13 Apr 2020

Novel coronavirus attacks and destroys T cells, just like HIV

The immune system has many components that work together in protecting the body from foreign invaders. One of the most important types of immune cells is T lymphocytes or T cells, a type of white blood cell that acts as the core of adaptive immunity, the system that modifies the immune response to specific pathogens.

13 Apr 2020

Missing COVID-19 antibodies suggest mystery immune response

Researchers at Shanghai Public Health Clinical Center have made important discoveries about the immune response among patients who have recovered from mild COVID-19 disease that could help to inform prevention and treatment methods, as well as improve the efficacy of community testing.

13 Apr 2020

UChicago Medicine launches clinical trial to explore plasma transfusions for COVID-19 patients

The University of Chicago Medicine is launching a clinical trial to study whether blood plasma from people who have recovered from COVID-19 can be used to treat patients who are still in the hospital with severe disease symptoms.

13 Apr 2020

Study looks into how malaria parasite evades the immune system

The parasite causing the most severe form of human malaria uses proteins to make red blood cells sticky, making it harder for the immune system to destroy it and leading to potentially fatal blood clots. New research at the Crick has identified how the parasite may control this process.

13 Apr 2020

Milk allergy guidelines may be linked to overdiagnosis in babies and children

Current medical guidelines for diagnosing cow's milk allergy in babies and young children may be linked to overdiagnosis of the condition.

13 Apr 2020

Remdesivir shows promise in post-infection treatment for COVID-19 disease

The coronavirus disease (COVID-19) has no approved treatment or vaccine as the world grapple with its wrath. The viral infection has so far infected 1.8 million and killed more than 114,000 people. Now, a team of scientists has shown that an experimental antiviral drug, remdesivir, has shown promise in treating patients with severe COVID-19.

13 Apr 2020

Lasers turn metal surfaces into bacteria killers

Purdue University researchers have discovered a laser treatment to texture metals that can potentially transform almost any metal surface into one that quickly eliminates any bacteria that come into contact with it.

12 Apr 2020

Stuttering DNA controls development of mosquito embryos

All organisms have DNA, the genetic material that provides a blueprint for life. The long double-helix-shaped DNA molecules in the body's cells are first translated into RNA molecules and then translated into proteins that ensure the functioning of the cell and the entire organism.

12 Apr 2020

Risks and benefits of separating infants from COVID-19-positive mothers

In a new commentary, Alison Stuebe, MD, President of the Academy of Breastfeeding Medicine, addresses the risks and benefits of separating infants from COVID-19-positive mothers following birth.

12 Apr 2020

Where cancers spread can give specific insights on disease traits

Kidney cancers that metastasize to the pancreas have a fundamentally different biology from those that metastasize elsewhere, with characteristics that can influence successful treatment, a study led by investigators with the UT Southwestern Kidney Cancer Program suggests.

12 Apr 2020

Novel clinical trial fast tracks testing of COVID-19 therapies

A novel clinical trial developed by researchers at the University of Pittsburgh School of Medicine launched today at UPMC to address one of the most important debates during the COVID-19 pandemic:

9 Apr 2020

What does recovery from COVID-19 look like? It depends. A pulmonologist explains.

Reports of recovery from serious illness caused by the coronavirus have been trickling in from around the world.

9 Apr 2020

'Off-the-shelf' artificial cardiac patch improves heart attack recovery in rat and pig models

Researchers from North Carolina State University have developed an "off-the-shelf" artificial cardiac patch that can deliver cardiac cell-derived healing factors directly to the site of heart attack injury. In a rat model of heart attack, the freezable, cell-free patch improved recovery.

8 Apr 2020

Philadelphia Eagles owner contributes $1 million to Penn Medicine to fight COVID-19 pandemic

Philadelphia Eagles owner Jeffrey Lurie today announced a $1 million contribution to Penn Medicine to establish the COVID-19 Immunology Defense Fund, laying the foundation for the world's foremost experts to fight the novel coronavirus pandemic.

8 Apr 2020