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RIG-1-like receptors may play dominant role in suppressing SARS-CoV-2 infection

A new study by researchers at the University of Connecticut Health Center, USA, reports the crucial nature of the pathogen pattern recognition receptor (PRRs), especially the two RLRs, retinoic acid-inducible gene I (RIG-I) and melanoma differentiation-associated protein 5 (MDA5), in triggering host cell immune responses within the cell. The RLRs are viral RNA sensors.

15 Feb 2021

Immunosuppressive therapies may be linked to severe COVID-19 in those with multiple sclerosis

A new study examines the associations between immunosuppressive disease-modifying therapies (DMTs) used in MS with adverse outcomes in an international cohort of patients with MS COVID-19.

15 Feb 2021

Only 25% of SARS-CoV-2 infections are detected in the UK: Study

A new preprint research paper posted to the medRxiv server estimates the number of infections that are diagnosed from testing alone as being about a fourth of the total.

15 Feb 2021

SARS-CoV-2's resistance to remdesivir in vitro

A new preprint research paper posted to the bioRxiv server discusses the emergence of mutations in the SARS-CoV-2 virus, allowing it to escape the effects of the most commonly used antiviral drug, remdesivir.

14 Feb 2021

S.D. governor gives state high marks in handling the pandemic. Are they deserved?

Covid-19 has pushed states to adopt unique approaches to protect their residents, but few have garnered as much scrutiny as South Dakota.

12 Feb 2021

Lessons learnt from the annual influenza season

Australian researchers have come up with two key recommendations from studies of the annual influenza season - one highlighting the benefits of antivirals in reducing repeat hospitalisation, and the other to watch for underlying cardiovascular disease.

12 Feb 2021

Statins shown to reduce COVID-19 severity and lower mortality

Much attention has been focused on ways to reduce the deadly exaggeration of normal inflammatory reactions to this pathogen. A new research paper posted to the medRxiv* preprint server describes the alleviation of hyper-inflammatory phenomena following the administration of statins, drugs more widely known for their use in reducing blood cholesterol levels, to patients with COVID-19.

11 Feb 2021

STING activation may be a new approach to reduce graft-versus-host disease

MUSC Hollings Cancer Center researcher Yongxia Wu, Ph.D., identified a new target molecule in the fight against graft-versus-host disease (GVHD).

11 Feb 2021

Duration of delirium in critically ill patients predicts mortality and disability

Delirium, a form of acute brain dysfunction, is widespread in critically ill patients in lower resourced hospitals, and the duration of delirium predicted both mortality and disability at six months after discharge, according to a study published in PLOS ONE.

11 Feb 2021

Adults with intellectual disabilities are particularly vulnerable to COVID-19, study finds

Researchers at the University of Glasgow and the Manchester Metropolitan University in the U.K. report that adults with intellectual disabilities have a higher risk of being infected with SARS-CoV2. They are also more likely to develop worse outcomes once infected.

11 Feb 2021

Short duration, poor-quality sleep may increase risk of dementia and earlier death in elderly people

Sleep and health are inextricably connected. New research from investigators at Brigham and Women's Hospital explores the connection between sleep disturbances and deficiencies among older adults and risk of dementia and death, finding that risk of dementia was double among participants who reported getting less than five hours of sleep compared to those who reported 7-8 hours of sleep per night.

11 Feb 2021

Study investigates influence of adequate supply of vitamin D on prognosis of numerous diseases

In recent years, three meta-analyses of clinical studies have come to the conclusion that vitamin D supplementation was associated with a reduction in the mortality rate from cancer of around 13 percent.

11 Feb 2021

1918 pandemic provides a cautionary tale of potential future pandemic

The 1918 influenza pandemic provides a cautionary tale for what the future may hold for COVID-19, says a Michigan State University researcher.

10 Feb 2021

Innovative collaboration applies state-of-the-art computation to medical care

An innovative partnership at The University of Texas at Austin takes aim at medicine down to the individual level by applying state-of-the-art computation to medical care.

10 Feb 2021

Researchers find higher odds of hospital readmission after endovascular aneurysm repair

Ruptured abdominal aortic aneurysms (rAAA) are responsible for nearly 2% of all deaths in U.S. men over the age of 65.

10 Feb 2021

Lung ultrasound helps predict clinical progression of severe COVID-19 patients

Lung ultrasound, considered a simple method for diagnosing lung disease, can also help predict the clinical progression of severe COVID-19 patients, according to a study conducted at the University of São Paulo's Medical School in São Paulo City, Brazil.

10 Feb 2021

Study finds increasing death rates from heart disease in young women

A nationwide US study has found increasing death rates from heart disease in women under 65. The research is published in European Heart Journal - Quality of Care and Clinical Outcomes, a journal of the European Society of Cardiology (ESC).

10 Feb 2021

Study reveals why Black men with prostate cancer have greater survival benefits from immunotherapy

Black men die more often of prostate cancer yet, paradoxically, have greater survival benefits from immunotherapy treatment.

10 Feb 2021

Study reveals how older environmentalists consider death care

Traditional burial in a graveyard has environmental costs.

9 Feb 2021

Acceptance of COVID-19 vaccine has increased significantly under Biden administration

Under the Biden Administration, New Yorkers' acceptance of the Covid-19 vaccine has increased significantly. In September, 55% of residents reported they would take the vaccine when it became available and this January, 64% reported they would take it.

9 Feb 2021

Mortality News and Research

RIG-1-like receptors may play dominant role in suppressing SARS-CoV-2 infection

Immunosuppressive therapies may be linked to severe COVID-19 in those with multiple sclerosis

Only 25% of SARS-CoV-2 infections are detected in the UK: Study

SARS-CoV-2's resistance to remdesivir in vitro

S.D. governor gives state high marks in handling the pandemic. Are they deserved?

Lessons learnt from the annual influenza season

Statins shown to reduce COVID-19 severity and lower mortality

STING activation may be a new approach to reduce graft-versus-host disease

Duration of delirium in critically ill patients predicts mortality and disability

Adults with intellectual disabilities are particularly vulnerable to COVID-19, study finds

Short duration, poor-quality sleep may increase risk of dementia and earlier death in elderly people

Study investigates influence of adequate supply of vitamin D on prognosis of numerous diseases

1918 pandemic provides a cautionary tale of potential future pandemic

Innovative collaboration applies state-of-the-art computation to medical care

Researchers find higher odds of hospital readmission after endovascular aneurysm repair

Lung ultrasound helps predict clinical progression of severe COVID-19 patients

Study finds increasing death rates from heart disease in young women

Study reveals why Black men with prostate cancer have greater survival benefits from immunotherapy

Study reveals how older environmentalists consider death care

Acceptance of COVID-19 vaccine has increased significantly under Biden administration

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Exploring the G:Box and for high-quality imaging

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