Immune System News and Research

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Gut bacteria can boost effectiveness of cancer immunotherapy, mice study suggests

Could the response to cancer immunotherapy depend on bacteria that originate in the gut and travel to the tumor?

7 Mar 2020

New 'Immuno-Engineering to Improve Immunotherapy' Center formed to advance cancer therapy

Harvard University's Wyss Institute of Biologically Inspired Engineering and its collaborating institutions, the Harvard John A. Paulson School of Engineering and Applied Sciences, Dana-Farber Cancer Institute, and Harvard's Department of Stem Cell and Regenerative Biology, announce the formation of a new NIH-funded Immuno-Engineering to Improve Immunotherapy Center.

7 Mar 2020

Researchers find link between interferon, neuroinflammation and synapse loss in Alzheimer's

When immunologist Dr. Wei Cao joined Baylor College of Medicine three-and-a-half years ago, her first project was to investigate how inflammation contributes to Alzheimer's disease.

5 Mar 2020

Researchers find previously unknown response within gut microbiome

The gut microbiome, which is a collection of numerous beneficial bacteria species, is key to our overall well-being and good health. Recent studies have linked the gut microbiome with several beneficial properties, such as aiding in the development of our immune system and warding off pathogen infections.

5 Mar 2020

Breakthrough technology identifies proteins' nearest neighbors on cell surfaces

When corporate partners in the Princeton Catalysis Initiative sat down two years ago with David MacMillan, they presented him with a biological challenge at the heart of potential cancer medicines and other therapeutics: which proteins on a cell's surface touch each other?

5 Mar 2020

New sepsis intervention enhances the body's bacteria-capturing neutrophil extracellular traps

Researchers at Children's Hospital of Philadelphia have developed a novel treatment for sepsis - one of the leading causes of hospital death - that enhances the body's bacteria-capturing neutrophil extracellular traps so that they more effectively capture infectious bacteria, resist degradation, and improve sepsis outcomes and survival.

5 Mar 2020

Social isolation could be linked to increased inflammation in the body

Social isolation could be associated with increased inflammation in the body new research from the University of Surrey and Brunel University London has found.

5 Mar 2020

Stress during pregnancy can cause lifetime of immune system deficiencies

Mice exposed to stress in the womb and soon after birth can expect a lifetime of immune system deficiencies that hinder the ability to ward off infections and cancer, Yale University researchers report March 5 in the journal Cell.

5 Mar 2020

New type of adoptive cell therapy could target prostate and pancreatic cancers in humans

In experiments with mice, researchers at the Johns Hopkins Kimmel Cancer Center say they have slowed the growth of transplanted human prostate and pancreatic cancer cells by introducing bone marrow cells with a specific gene deletion to induce a novel immune response.

5 Mar 2020

New approach may lead to targeted treatments for certain macrophages or their mechanisms

Can phagocytes act like a Trojan horse, transporting tumour cells within themselves and thereby causing metastases in cancer patients?

5 Mar 2020

New repair mechanism for alcohol-induced DNA damage discovered

Researchers of the Hubrecht Institute in Utrecht, The Netherlands, and the MRC Laboratory of Molecular Biology in Cambridge, United Kingdom, have discovered a new way in which the human body repairs DNA damage caused by a degradation product of alcohol.

4 Mar 2020

Cesarean delivery has little impact on development of childhood allergic diseases

A cesarean birth had little impact on whether a child would go onto develop allergies, a new study led by the Murdoch Children's Research Institute has shown.

4 Mar 2020

Novel drug to arrest antibiotic resistance by preventing micro-evolution

Desperate times need desperate measures. Accordingly, scientists, today published a new study in the journal Cell Host and Microbe in March 2020, showing that drugs that prevent the acquisition of DNA-borne antibiotic resistance traits from their surroundings by bacteria can stop mice from becoming resistant to the action of the antibiotics.

3 Mar 2020

Inhibiting energy production in immune T-cells allows some tumors to escape treatment

A small molecule that inhibits energy production in immune T-cells allows some tumors to escape treatment with an immunotherapy called PD-1 blockade therapy, says a study in mice published today in eLife.

3 Mar 2020

The research and development costs of a new drug

Many recent studies have focused on how much it costs to bring a new drug to market in the light of increasing drug prices. Estimates range from $314 million to $2.8 billion. Most of this was based on proprietary data and was, therefore, not verifiable independently, attracting much criticism.

3 Mar 2020

Maternal psychological distress during pregnancy influences child's gut immunity

A woman's mental health during pregnancy has a direct influence on the development of her child's immune system, according to a new study from pediatric researchers at the University of Alberta.

3 Mar 2020

Inhibiting specific protein could make radiation therapy for colon cancer more effective

Researchers at Washington University School of Medicine in St. Louis appear to have discovered a way to make radiation therapy for colorectal cancer more effective by inhibiting a protein found in cancer cells in the gut.

3 Mar 2020

Obesity could increase severity of influenza study shows

A new study has revealed that those who are obese or overweight tend to get more severe bouts of influenza than those who are a healthy weight. The reason behind this could be the altered immune system of those who are obese. The study outlining this finding is published in the latest issue of the journal mBio from the American Society for Microbiology (ASM). The study was titled, "Obesity-Related Microenvironment Promotes Emergence of Virulent Influenza Virus Strains."

3 Mar 2020

Two common Staph bacteria living on human skin exacerbate Netherton syndrome

Netherton syndrome, a rare skin disease caused by a single genetic mutation, is exacerbated by the presence of two common Staphylococcal bacteria living on human skin, one of which was previously thought to only offer protective properties, report University of California San Diego School of Medicine researchers.

3 Mar 2020

Blocking immune T-cell regulator may help boost tumor killing, study shows

Immune system T-cells are more able to destroy skin cancer cells when a T-cell regulator called SLAMF6 is missing, a new study in eLife shows.

3 Mar 2020

Immune System News and Research

Gut bacteria can boost effectiveness of cancer immunotherapy, mice study suggests

New 'Immuno-Engineering to Improve Immunotherapy' Center formed to advance cancer therapy

Researchers find link between interferon, neuroinflammation and synapse loss in Alzheimer's

Researchers find previously unknown response within gut microbiome

Breakthrough technology identifies proteins' nearest neighbors on cell surfaces

New sepsis intervention enhances the body's bacteria-capturing neutrophil extracellular traps

Social isolation could be linked to increased inflammation in the body

Stress during pregnancy can cause lifetime of immune system deficiencies

New type of adoptive cell therapy could target prostate and pancreatic cancers in humans

New approach may lead to targeted treatments for certain macrophages or their mechanisms

New repair mechanism for alcohol-induced DNA damage discovered

Cesarean delivery has little impact on development of childhood allergic diseases

Novel drug to arrest antibiotic resistance by preventing micro-evolution

Inhibiting energy production in immune T-cells allows some tumors to escape treatment

The research and development costs of a new drug

Maternal psychological distress during pregnancy influences child's gut immunity

Inhibiting specific protein could make radiation therapy for colon cancer more effective

Obesity could increase severity of influenza study shows

Two common Staph bacteria living on human skin exacerbate Netherton syndrome

Blocking immune T-cell regulator may help boost tumor killing, study shows

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