Chromosome 4 News and Research

RSS

Humans normally have 46 chromosomes in each cell, divided into 23 pairs. Two copies of chromosome 4, one copy inherited from each parent, form one of the pairs. Chromosome 4 spans more than 191 million DNA building blocks (base pairs) and represents more than 6 percent of the total DNA in cells.

Identifying genes on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 4 likely contains between 1,300 and 1,600 genes.

Genes on chromosome 4 are among the estimated 20,000 to 25,000 total genes in the human genome.

Radiation after surgery in children with ependymoma nearly triples survival rate

Radiation immediately following surgery in children with ependymoma, the third most common pediatric brain tumor, can nearly triple survival.

5 Mar 2019

Research on mosaic embryos gives new hope to people seeking infertility treatments

Not every embryo contains 46 perfect chromosomes. Some have more, others have fewer. The result is a common abnormality known as aneuploidy, which occurs in as many as 80 percent of human embryos.

5 Mar 2019

Second-ever case of semi-identical (sesquizygotic) twins

Doctors report on a woman who gave birth to semi-identical twins in 2014. This is the second time this is known to have occurred after the first case in 2007.

28 Feb 2019

Breakthrough chromosome imaging could aid in development of new treatments

Chromosomes, each containing hundreds or thousands of genes, act like a detailed instruction manual for how cells should develop and behave.

28 Feb 2019

Johns Hopkins researchers find genetic cause of olfactory neuroblastoma

By sequencing the entire genomes of tumor cells from six people with a rare cancer of the nose and sinus cavity, Johns Hopkins researchers report they unexpectedly found the same genetic change¾one in a gene involved in muscle formation¾in five of the tumors.

28 Feb 2019

Study finds specific mechanism that protects cells from natural DNA errors

Researchers from the University of Copenhagen have identified a specific mechanism that protects our cells from natural DNA errors - an 'enemy within' - which could permanently damage our genetic code and lead to diseases such as cancer.

27 Feb 2019

Biologists uncover mechanism that determines faithful inheritance of short chromosomes

A team of biologists has uncovered a mechanism that determines faithful inheritance of short chromosomes during the reproductive process.

27 Feb 2019

New test could be a ‘game changer’ in the treatment of chronic lymphocytic leukemia

The first test to quickly and accurately predict how people will respond to standard treatment for the most common type of leukemia has been developed at Cardiff University. The technology could guide doctors’ decisions on which drugs to give to patients.

27 Feb 2019

'Chromosome scanner' that protects against cancer identified

In a new study, researchers from the University of Copenhagen have identified one of the main mechanisms behind the repair of serious damage to the human DNA. A 'scanner' inside the cells decides whether or not so-called flawless DNA repair, which protects against cancer, is launched.

26 Feb 2019

New blood test detects genetic disorders in fetuses

Tel Aviv University researchers have developed a new blood test for genetic disorders that may allow parents to learn about the health of their baby as early as 11 weeks into pregnancy.

21 Feb 2019

Study finds new genetic clues associated with asthma in African ancestry populations

In the largest study of its kind, researchers at the University of Colorado Anschutz Medical Campus have found new clues into the parts of the human genome associated with the higher rates of asthma in those of African ancestry.

21 Feb 2019

Researchers identify multiple genetic variants associated with body fat distribution

A new breakthrough from the Genetic Investigation of Anthropometric Traits consortium, which includes many public health researchers from the University of North Carolina at Chapel Hill, identifies multiple genetic variants associated with how the body regulates and distributes body-fat tissue.

18 Feb 2019

Conformance of genetic characteristics found to be crucial for longer preservation of kidney graft

The conformance of genetic characteristics is essential for the long-term function after kidney transplantation. This is the central result of a recent study in the top journal “The Lancet” with more than 500 patients after kidney transplantation, conducted by a global consortium led by Rainer Oberbauer and his colleagues Roman Reindl-Schwaighofer and Andreas Heinzel from the Division of Nephrology and Dialysis at MedUni Vienna.

15 Feb 2019

Study reveals how one mutation causes the most common inherited intellectual disability

Research published today (Feb. 11, 2019) reveals how one mutation causes fragile X, the most common inherited intellectual disability.

12 Feb 2019

Researchers map extremely complex chromosome aberrations using DNA puzzle pieces

Using puzzle pieces from four different DNA analyses, researchers at Karolinska Institutet in Sweden have been able to map three extremely complex chromosome aberrations.

12 Feb 2019

Researchers identify genes that make Staphyloccocus bacteria resistant to treatment

A Rutgers-led team has discovered two genes that make some strains of harmful Staphyloccocus bacteria resistant to treatment by copper, a potent and frequently used antibacterial agent.

11 Feb 2019

Researchers reveal novel computational tool used to analyze genetic variation

The field of genetic sequencing has undergone a dramatic revolution over the past 20 years. In 2001 the first copy of the three billion base pairs that assemble the human genome was published.

8 Feb 2019

Zebrafish offers clue to alleviate gastrointestinal distress related to autism

University of Miami researchers have discovered a clue in the humble zebrafish's digestive tract that, one day, could help people on the autism spectrum alleviate one of the most common yet least studied symptoms of their disorder: gastrointestinal distress.

7 Feb 2019

Cannabinoid receptor type 1 appears to be potential target to treat Down syndrome

A study by the Neuropharmacology Laboratory-NeuroPhar of the Department of Experimental and Health Sciences at UPF reveals the involvement of the endocannabinoid system in cognitive disorders in mouse models of Down syndrome.

7 Feb 2019

Study: BldC protein in Streptomyces acts as ‘brake’ to control timing of sporulation

Streptomyces are soil-dwelling bacteria that produce approximately two-thirds of the antibiotics in current clinical use.

6 Feb 2019

Chromosome 4 News and Research

Further Reading

Radiation after surgery in children with ependymoma nearly triples survival rate

Research on mosaic embryos gives new hope to people seeking infertility treatments

Second-ever case of semi-identical (sesquizygotic) twins

Breakthrough chromosome imaging could aid in development of new treatments

Johns Hopkins researchers find genetic cause of olfactory neuroblastoma

Study finds specific mechanism that protects cells from natural DNA errors

Biologists uncover mechanism that determines faithful inheritance of short chromosomes

New test could be a ‘game changer’ in the treatment of chronic lymphocytic leukemia

'Chromosome scanner' that protects against cancer identified

New blood test detects genetic disorders in fetuses

Study finds new genetic clues associated with asthma in African ancestry populations

Researchers identify multiple genetic variants associated with body fat distribution

Conformance of genetic characteristics found to be crucial for longer preservation of kidney graft

Study reveals how one mutation causes the most common inherited intellectual disability

Researchers map extremely complex chromosome aberrations using DNA puzzle pieces

Researchers identify genes that make Staphyloccocus bacteria resistant to treatment

Researchers reveal novel computational tool used to analyze genetic variation

Zebrafish offers clue to alleviate gastrointestinal distress related to autism

Cannabinoid receptor type 1 appears to be potential target to treat Down syndrome

Study: BldC protein in Streptomyces acts as ‘brake’ to control timing of sporulation

Shaping the Future of Neuroscience: A Conversation with Atlas Antibodies on the MolBoolean™ and the Impact of SfN 2024

How the Arts Reshape Brain Function: Susan Magsamen on the Future of Neuroaesthetics

Inside the Alzheimer's Association: Dr. Heather Snyder on Driving Research and Collaboration

Latest News