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Temple, Case Western scientists receive $3 million NIH grant to study pathway behind heart failure

Like a bad water pump that fails to circulate coolant in a car engine, a failing heart struggles to pump blood through the body, causing symptoms of fatigue, shortness of breath, and swelling in the legs and feet.

5 Apr 2021

FIND announces launch of a request for proposals to expand access to COVID-19 testing services

The Foundation for Innovative New Diagnostics (FIND) announced today the launch of a request for proposals (RFP) to accelerate the development, manufacturing, and market availability of accurate, affordable, quality-assured and easy-to-use SARS-CoV-2 self-tests for use in low- and middle-income countries (LMICs).

5 Apr 2021

Combination of tumor cell vaccine and checkpoint therapy creates effective immune response

A personalized tumor cell vaccine strategy targeting Myc oncogenes combined with checkpoint therapy creates an effective immune response that bypasses antigen selection and immune privilege, according to a pre-clinical study for neuroblastoma and melanoma.

3 Apr 2021

Massive X-ray screening identifies several candidates for drugs against novel coronavirus

A team of researchers has identified several candidates for drugs against the coronavirus SARS-CoV-2 at DESY´s high-brilliance X-ray lightsource PETRA III.

3 Apr 2021

Scientists identify nine potential new COVID-19 treatments

A team led by scientists in the Perelman School of Medicine at the University of Pennsylvania has identified nine potential new COVID-19 treatments, including three that are already approved by the Food and Drug Administration (FDA) for treating other diseases.

2 Apr 2021

Suppressing facial expressions may be useful in certain contexts, shows study

How do our facial expressions in response to seeing others in pain influence how we see and feel their pain? There are many situations where it may be helpful to suppress our emotional responses to the pain of others.

2 Apr 2021

Mimes help humans to “see” objects that are invisible

When we watch a mime seemingly pull rope, climb steps or try to escape that infernal box, we don't struggle to recognize the implied objects -- our minds automatically "see" them, a new study concludes.

2 Apr 2021

Mice experiencing hallucination-like events provide clues to understand psychosis

The humble lab mouse has provided invaluable clues to understanding diseases ranging from cancer to diabetes to COVID-19. But when it comes to psychiatric conditions, the lab mouse has been sidelined, its rodent mind considered too different from that of humans to provide much insight into mental illness.

1 Apr 2021

HCAs are a promising risk indicator of type 2 diabetes

A series of studies led by researchers from Hong Kong Baptist University have revealed that hyocholic acid and its derivatives (collectively known as HCAs), a component of bile acids that facilitate fat digestion, are a promising risk indicator of type 2 diabetes.

1 Apr 2021

Researchers develop new AI-based strategy to assess beef freshness

Although beef is one of the most consumed foods around the world, eating it when it's past its prime is not only unsavory, but also poses some serious health risks.

1 Apr 2021

Glycans influence SARS-CoV-2 spike–ACE2 binding affinity, finds study

A study conducted at the Los Alamos National Laboratory, USA, and Concordia University, Canada, has explored the impact of different types of glycans on the interaction between SARS-CoV-2 spike protein and human ACE2 receptor.

1 Apr 2021

Temperature difference in the upper and lower respiratory tract influences SARS-CoV-2 replication

A team of researchers from the Institute for Infectious Diseases (IFIK) at the University of Bern and the Federal Institute of Virology and Immunology (IVI) have assessed virus growth and activation of the cellular defense mechanisms in the respiratory tract.

1 Apr 2021

Evidence-based clinical practice guideline aims to optimize PD-L1 lung tumor testing

The College of American Pathologists (CAP), in collaboration with five other societies, developed a draft evidence-based clinical practice guideline that aims to optimize PD-L1 testing for patients with non-small cell lung cancer (NSCLC) who are being considered for immunooncology therapy.

1 Apr 2021

Oxford-AstraZeneca vaccine effective against B.1.1.7 SARS-CoV-2 variant

Published in The Lancet, the study explores if the Oxford-AstraZeneca vaccine works well in protecting against the B.1.1.7 variant, otherwise known as the U.K. variant.

31 Mar 2021

CDC and NIH launch community COVID-19 testing initiative

The Centers for Disease Control and Prevention, in collaboration with the National Institutes of Health, has launched an innovative community health initiative called "Say Yes! COVID Test" starting in Pitt County, North Carolina, and coming soon to Chattanooga/Hamilton County Tennessee.

31 Mar 2021

New portable viral screening test can diagnose COVID-19 in minutes and track variants

Clinicians using a new viral screening test can not only diagnose COVID-19 in a matter of minutes with a portable, pocket-sized machine, but can also simultaneously test for other viruses--like influenza--that might be mistaken for the coronavirus.

31 Mar 2021

Beckman Coulter life sciences brightens flow cytometry with new SuperNova polymer dyes portfolio

The world of flow cytometry is getting brighter as Beckman Coulter Life Sciences debuts its new SuperNova polymer dyes, featuring increased brightness and an improved staining index, which can enhance results in critical laboratory tests.

From Beckman Coulter Life Sciences - Flow Cytometry 31 Mar 2021

Scientists discover new genetic disease that causes abnormal brain development in children

Scientists have discovered a new genetic disease, which causes some children's brains to develop abnormally, resulting in delayed intellectual development and often early onset cataracts.

31 Mar 2021

COVID-19 associated seizures may increase death risk in patients

COVID-19 can have damaging effects on multiple organs in the body, including the brain. A new study led by investigators at Massachusetts General Hospital (MGH) and Beth Israel Deaconess Medical Center (BIDMC) indicates that some hospitalized patients with COVID-19 experience non-convulsive seizures, which may put them at a higher risk of dying. The findings are published in the Annals of Neurology.

31 Mar 2021

Soft X-ray microscopy shows how viral pathogens penetrate human cells

How do viral pathogens succeed in penetrating human cells? Which cellular mechanisms do they use to multiply efficiently and, in doing so, how do they change the structure of their host cell? These questions are the focus of a pan-European research project called "Compact Cell-Imaging Device" (CoCID), in which Heidelberg scientists are playing a major role.

31 Mar 2021

Laboratory News and Research

Temple, Case Western scientists receive $3 million NIH grant to study pathway behind heart failure

FIND announces launch of a request for proposals to expand access to COVID-19 testing services

Combination of tumor cell vaccine and checkpoint therapy creates effective immune response

Massive X-ray screening identifies several candidates for drugs against novel coronavirus

Scientists identify nine potential new COVID-19 treatments

Suppressing facial expressions may be useful in certain contexts, shows study

Mimes help humans to “see” objects that are invisible

Mice experiencing hallucination-like events provide clues to understand psychosis

HCAs are a promising risk indicator of type 2 diabetes

Researchers develop new AI-based strategy to assess beef freshness

Glycans influence SARS-CoV-2 spike–ACE2 binding affinity, finds study

Temperature difference in the upper and lower respiratory tract influences SARS-CoV-2 replication

Evidence-based clinical practice guideline aims to optimize PD-L1 lung tumor testing

Oxford-AstraZeneca vaccine effective against B.1.1.7 SARS-CoV-2 variant

CDC and NIH launch community COVID-19 testing initiative

New portable viral screening test can diagnose COVID-19 in minutes and track variants

Beckman Coulter life sciences brightens flow cytometry with new SuperNova polymer dyes portfolio

Scientists discover new genetic disease that causes abnormal brain development in children

COVID-19 associated seizures may increase death risk in patients

Soft X-ray microscopy shows how viral pathogens penetrate human cells

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