Immune System News and Research

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Sex-specific differences in the immune system may explain men's susceptibility to obesity

Melbourne researchers have uncovered important differences between the male and female immune system which may explain why men are more susceptible to obesity and metabolism-related associated diseases, such as heart disease, stroke and diabetes.

26 Feb 2020

HKUST scientists provide leads for guiding research towards COVID-19 vaccine development

A team of scientists at the Hong Kong University of Science and Technology (HKUST) has recently made an important discovery in identifying a set of potential vaccine targets for the SARS-CoV-2 coronavirus, providing crucial leads for guiding experimental efforts towards the vaccine development against the novel pneumonia (COVID-19) caused by the virus.

26 Feb 2020

Cellular metabolism plays key role in dictating the fate decision between pathogenic and regulatory T cells

Patients with autoimmune diseases like multiple sclerosis, inflammatory bowel disease and rheumatoid arthritis have an imbalance between two types of immune system T cells.

26 Feb 2020

Study sheds new light on the immune system’s ability to deal with co-infection

The body’s immune response to fungal infections changes when a patient is also infected by a virus, according to new research which investigated the two types of infection together for the first time.

26 Feb 2020

Aggressive cancers set up a structural framework to keep the immune system at bay

Aggressive colorectal cancers set up an interactive network of checkpoints to keep the immune system at bay, scientists report.

26 Feb 2020

Ulcerative colitis and a missing microbe in the gut

Ulcerative colitis is a seriously debilitating inflammatory disease of the bowel leading to crippling symptoms that can affect the quality of life severely. Researchers from Stanford University School of Medicine have found in a new study that a missing microbe could be linked to this condition. The study was published today in the latest issue of the journal Cell Host & Microbe.

25 Feb 2020

Researchers reveal new details about how joint inflammation evolves in rheumatoid arthritis

Walter and Eliza Hall Institute researchers have revealed new details about how joint inflammation evolves in rheumatoid arthritis, and the cells that prolong the inflammatory attack.

25 Feb 2020

Effects of obesity mirror those of aging, study shows

Globally, an estimated 1.9 billion adults and 380 million children are overweight or obese. According to the World Health Organization, more people are dying from being overweight than underweight. Researchers at Concordia are urging health authorities to rethink their approach to obesity.

25 Feb 2020

Scientists developing a combined vaccine to fight most malignant brain tumor

Scientists are developing a combined vaccine to fight the most deadly form of brain cancer.

25 Feb 2020

Scientists join forces to combat coronavirus outbreak

Amid the coronavirus disease (COVID-19) outbreak, scientists from around the globe race to fight the deadly virus. Now, a team of Harvard scientists has joined forces with Chinese experts to develop new therapies and prevent the further spread of the virus.

25 Feb 2020

Researchers identify mechanisms underlying immunotherapy-associated tuberculosis

Researchers at the University of Southampton have identified how new checkpoint inhibitor treatments for cancer can activate tuberculosis in some patients.

24 Feb 2020

Small molecules may open the door to new therapies for Duchenne muscular dystrophy

Researchers identified a group of small molecules that may open the door to developing new therapies for Duchenne muscular dystrophy, an as-yet-uncured disease that results in devastating muscle weakening and loss.

24 Feb 2020

Autoantibodies can also act as the body's own antidepressants

If the immune system attacks its own body, it can often have devastating consequences: autoantibodies bind to the body's structures, triggering functional disorders.

24 Feb 2020

Scientific breakthrough provides insights into basic mechanisms of allergic reactions

An international research team has been able to describe the overall structure of the antibody type IgE, which is the key molecule in allergic diseases.

24 Feb 2020

Inflammation caused by radiation can promote survival of triple-negative breast cancer cells

While radiation is successfully used to treat breast cancer by killing cancer cells, inflammation caused as a side-effect of radiation can have a contrary effect by promoting the survival of triple-negative breast cancer cells, according to research published online in the International Journal of Radiation Biology by Jennifer Sims-Mourtada, Ph.D., director of Translational Breast Cancer Research at ChristianaCare's Helen F. Graham Cancer Center & Research Institute.

24 Feb 2020

UCI makes tremendous strides in prevention, early detection and treatment of cancer

Like most people, John Gifford wasn't looking forward to a colonoscopy when he arrived on the UCI Medical Center campus in Orange in 2018.

23 Feb 2020

UCI neuro-oncologist uses comprehensive approach to battle brain cancer

When you're facing a cancer diagnosis with an average survival span of 12 to 18 months, every milestone is a victory.

23 Feb 2020

Using newly discovered immune cell type to fight pancreatic cancer

Immunotherapy is showing great promise for treating cancer. But so far, this approach has been effective in only about 20% of all cancers. To advance those results, researchers are looking for new ways to mobilize the immune system to destroy tumors.

23 Feb 2020

Comprehensive tumor profiling reveals why osteosarcoma does not respond to immunotherapy

Comprehensive profiling of tumor samples taken from patients with osteosarcoma shows that multiple factors contribute to the traditionally poor responses observed from treatment with immune checkpoint inhibitors, according to new research from The University of Texas MD Anderson Cancer Center.

22 Feb 2020

A step towards precision medicine for the management of monogenic diabetes

Diabetes affects more than 400 million people worldwide and is a major public health problem. Although commonly referred to as a single disease, it actually constitutes a group of metabolic disorders with hyperglycemia as a common feature. Of all its forms, monogenic diabetes - due to a mutation in one of the genes involved in the management of blood sugar levels - affects 1% to 4% of all cases of diabetes.

22 Feb 2020

Immune System News and Research

Sex-specific differences in the immune system may explain men's susceptibility to obesity

HKUST scientists provide leads for guiding research towards COVID-19 vaccine development

Cellular metabolism plays key role in dictating the fate decision between pathogenic and regulatory T cells

Study sheds new light on the immune system’s ability to deal with co-infection

Aggressive cancers set up a structural framework to keep the immune system at bay

Ulcerative colitis and a missing microbe in the gut

Researchers reveal new details about how joint inflammation evolves in rheumatoid arthritis

Effects of obesity mirror those of aging, study shows

Scientists developing a combined vaccine to fight most malignant brain tumor

Scientists join forces to combat coronavirus outbreak

Researchers identify mechanisms underlying immunotherapy-associated tuberculosis

Small molecules may open the door to new therapies for Duchenne muscular dystrophy

Autoantibodies can also act as the body's own antidepressants

Scientific breakthrough provides insights into basic mechanisms of allergic reactions

Inflammation caused by radiation can promote survival of triple-negative breast cancer cells

UCI makes tremendous strides in prevention, early detection and treatment of cancer

UCI neuro-oncologist uses comprehensive approach to battle brain cancer

Using newly discovered immune cell type to fight pancreatic cancer

Comprehensive tumor profiling reveals why osteosarcoma does not respond to immunotherapy

A step towards precision medicine for the management of monogenic diabetes

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