Colon News and Research

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Taller adults may be more likely to develop colorectal cancer, study finds

A new meta-analysis, or data examination of several independent studies, by Johns Hopkins Medicine researchers adds to evidence that taller adults may be more likely than shorter ones to develop colorectal cancer or colon polyps that can later become malignant.

3 Mar 2022

AI and machine learning could improve cancer diagnosis through biomarker discovery

Artificial intelligence (AI), deep learning (DL), and machine learning (ML) have transformed many industries and areas of science.

1 Mar 2022

Genetic analysis reveals eosinophilic colitis as a unique disease

A condition called eosinophilic colitis is distinct from other, similar eosinophilic gastrointestinal diseases and inflammatory bowel disease, according to a genetic analysis published in Gastroenterology.

24 Feb 2022

Novel platform can become a potential approach for personalized cancer treatments

Killing cancer cells without affecting surrounding normal cells is the most desirable approach for targeted cancer therapy. However, it cannot be easily achieved due to the similarities in the properties between normal and cancer cells.

22 Feb 2022

Scientists use entire human GI tracts to shed light on cellular functions

If you get nervous, you might feel it in your gut. If you eat chili, your gut might revolt, but your friend can eat anything and feel great. You can pop ibuprofen like candy with no ill effects, but your friend's belly might bleed and she might get no pain relief.

21 Feb 2022

The logic that controls gene regulation in human cells discovered

A research group at the University of Helsinki has discovered the logic that controls gene regulation in human cells. In the future, this new knowledge can be applied to, for example, investigating cancers and other genetic diseases.

21 Feb 2022

Research shows alterations in transfer RNAs at the epigenetic level in cancer

A recently published paper in the journal Molecular Cancer by the group of Dr. Manel Esteller, Director of the Josep Carreras Leukaemia Research Institute, ICREA Research Professor and Genetics Chairman at the University of Barcelona, shows that transfer RNAs for certain amino acids are altered at the epigenetic level in some types of cancer, expressing it in an exaggerated manner in some cases and being deficient in others.

17 Feb 2022

Global human microbiome research dominated by highly developed countries

New studies emerge daily on the effect of the human microbiome on human health: colon cancer, ulcers, and cognitive conditions such as Alzheimer's disease have been associated with the communities of microbes that live in our bodies.

16 Feb 2022

U-M researchers measure out-of-pocket costs for follow-up tests after free cancer screening

With the White House putting cancer prevention and early treatment squarely in the sights of its renewed Cancer Moonshot initiative, recent University of Michigan research offers insights that policymakers could use to ensure more cancers are diagnosed earlier and reduce inequalities.

15 Feb 2022

Spatial transcriptomics-driven gene mapping offers new insights into inflammatory bowel disease

Using a technique called spatial transcriptomics, researchers at Karolinska Institutet in Sweden have analyzed the gene expression in the mouse colon and created a map showing where in the tissue individual genes are expressed.

12 Feb 2022

Molecular treatment works against metastatic cancer that spread to the brain

Mount Sinai researchers conducting clinical trials of a drug targeting a cancer gene found that it increased metastatic cancer patients' survival and was able to work within the brain, according to a study published in Clinical Cancer Research in February.

10 Feb 2022

New protocol for transplanting 3D cellular structures to regenerate damaged intestinal tissue

Ulcerative colitis is an inflammatory bowel disease (IBD) that causes inflammation and ulcers (sores) in the digestive tract. Ulcerative colitis affects the innermost lining of the colon and rectum.

10 Feb 2022

Scientists identify a new protein that prevents cancer cell migration

When tumors spread, cancer cells migrate to other parts of the body through the blood or lymphatic vessels. Scientists at the Institute of Science and Technology Austria have now found a new protein that prevents cancer cells from doing so by making them stick more tightly to their surroundings.

9 Feb 2022

Reducing mucin secretion provides a way to control chemoresistance of colorectal cancers

Drugs which are commonly-used as the first line of treatment for colorectal cancer cause the tumor cells to oversecrete proteins known as mucins, according to a new study published today in the journal eLife.

9 Feb 2022

New kind of surgical duct tape can help seal tears and wounds

A staple on any engineer's workbench, duct tape is a quick and dependable fix for cracks and tears in many structural materials.

2 Feb 2022

Study uncovers a class of microbial enzymes that drive ulcerative colitis

Ulcerative colitis, a subtype of inflammatory bowel disease, is a chronic ailment of the colon affecting nearly one million individuals in the United States. It is thought to be linked to disruptions in the gut microbiome -; the bacteria and other microbes that live inside us -; but no existing treatments actually target these microorganisms.

2 Feb 2022

Weight loss by overweight and obese people associated with reduced risk of colorectal adenoma

A new paper in JNCI Cancer Spectrum, published by Oxford University Press, indicates that overweight and obese people who lose weight may reduce their chances of later developing colorectal adenoma – a type of benign growth or polyp in the colon or rectum that could lead to colorectal cancer.

1 Feb 2022