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Gene's role in immune system may suggest new treatments for childhood asthma

Pediatric researchers have identified a novel gene involved in childhood asthma, in one of the largest gene studies to date of the common respiratory disease. Because the gene, called DENND1B, affects cells and signaling molecules thought to be instrumental in the immune system overreaction that occurs in asthma, the discovery may have singled out an important target for new treatments.

23 Dec 2009

Scientists use DNA sequence to characterize genome rearrangement in breast cancer samples

The first detailed search of breast cancer genomes to uncover genomic rearrangements is published today. The team characterised the ways in which the human genome is broken and put back together in 24 cases of breast cancer.

23 Dec 2009

New findings show ether discovery might have occurred earlier

The successful use of ether to anesthetize patients was the first great milestone in the history of surgical anesthesia. But the discovery might have occurred earlier—and medical history written differently—but for a scientific error by another physician, according to an article in the January issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

23 Dec 2009

Volcano lauds revised guidelines for treating severe coronary artery disease patients

Volcano Corporation, a leader in the development, manufacturing and sales of products for the diagnosis and treatment of coronary and peripheral artery disease, reacted positively to the new guidelines for treating coronary disease and heart attacks using percutaneous coronary intervention (PCI), a procedure that treats narrowed blood vessels.

23 Dec 2009

Otsuka America Pharmaceutical joins NPC

The National Pharmaceutical Council (NPC) today announced that Otsuka America Pharmaceutical, Inc. has joined the health policy research organization as a member.

23 Dec 2009

TGLN responds to CIHI report on organ donation

The Canadian Institute for Health Information (CIHI) report that was issued this afternoon, understandably, takes a national perspective, and uses a conventional 10 year time frame.

23 Dec 2009

Mediware Information Systems introduces new system interface to the U.S. Biovigilance Network

Continuing its diligent focus on patient safety, Mediware Information Systems, Inc. has announced the availability of a new system interface that will enable customers using the Company's LifeTrak® blood donor management software to electronically transmit blood donation data to the U.S. Biovigilance Network.

23 Dec 2009

Findings may lead to new methods for diagnosing osteoporosis

Using a technique that provides detailed images of nanoscale structures, researchers at the University of Michigan and Detroit's Henry Ford Hospital have discovered changes in the collagen component of bone that directly relate to bone health.

23 Dec 2009

New CIHI study highlights that Canada needs to retrieve more organs for transplants

The availability of donated organs in Canada rose by more than one-quarter (28%) over the past decade, but this increase is not keeping pace with demand. More than 1,000 Canadians donated organs in 2008, up from 812 in 1999, according to a new study released today by the Canadian Institute for Health Information (CIHI).

23 Dec 2009

Nationwide Children's Hospital chosen as a BCR for TCGA

Nationwide Children's Hospital recently was awarded an initial $5.5 million contract from the National Cancer Institute (NCI) to serve as a Biospecimen Core Resource (BCR) for The Cancer Genome Atlas (TCGA), a program co-managed by the NCI and the National Human Genome Research Institute (NHGRI), both part of the National Institutes of Health (NIH).

23 Dec 2009

Novel discovery offers hope for patients with common brain tumor

Biomedical researchers at the University of Central Florida have found a protein that could hold the key to treating one of the most common and aggressive brain tumors in adults.

23 Dec 2009

Autism study and gene therapy in vision are top scientific achievements in 2009

A landmark autism study and a dramatic success for gene therapy in reversing inherited blindness, both at The Children's Hospital of Philadelphia, were recognized among the top scientific achievements in 2009, according to three national publications: Time magazine, Discover magazine and the journal Science.

23 Dec 2009

Beta blockers may increase risk of anemia-induced adverse cardiovascular events

Routinely used to treat patients for heart attack or high blood pressure, beta blockers are known for their role in helping to protect the heart. A new study in the January issue of the journal Anesthesiology looks at the effects of beta blockers on surgical outcomes, revealing that the cardioprotective effects of the medication could be compromised by acute surgical anemia.

23 Dec 2009

Embryo biopsy safe for singleton pregnancies

The largest and longest running study of children born after preimplantation genetic diagnosis and screening has shown that embryo biopsy does not adversely affect the health of babies born as the result of a subsequent singleton pregnancy.

23 Dec 2009

ARCA biopharma submits Gencaro trial protocol for review under the FDA’s SPA process

ARCA biopharma, Inc. today announced that it has submitted a study protocol for review under the U.S. Food and Drug Administration’s (FDA) Special Protocol Assessment (SPA) process for the design of a clinical trial to assess the safety and efficacy of GencaroTM, in approximately 3,000 patients with chronic heart failure who have the genotype that appears to respond most favorably to Gencaro. Gencaro is the Company’s investigational, pharmacologically unique beta-blocker and mild vasodilator.

23 Dec 2009

NHLBI grant for identifying genetic and epigenetic causes of human congenital heart disease

Researchers at Children's Hospital Boston and Brigham and Women's Hospital have received funding from the National Heart, Lung, and Blood Institute (NHLBI) to support their search for undiscovered gene defects that cause congenital heart disease. The $4.19 million, 6-year grant is part of the Pediatric Cardiac Genomics Consortium (PCGC), which seeks to identify genetic and epigenetic causes of human congenital heart disease, and relate genetic variants present in the congenital heart disease patient population to clinical outcomes.

23 Dec 2009

Benefits of dispatcher-assisted bystander CPR outweigh potential injury risks

Dispatchers should assertively give cardiopulmonary resuscitation (CPR) instructions to bystanders who suspect someone is in cardiac arrest because the benefits from correctly recommending CPR for someone who needs it greatly outweigh the risks from recommending CPR for someone who does not, researchers said in Circulation: Journal of the American Heart Association.

23 Dec 2009

Second successful phrenic nerve decompression surgery

The Plastic Surgery Center today announced that immediately following a rare phrenic nerve surgery to repair his paralyzed diaphragm, a 47-year-old man has reported significantly improved breathing and feels “15 years younger.” The surgery marked the second known case of successful phrenic nerve decompression, both of which were performed by a New Jersey medical team led by Dr. Matthew Kaufman of the Plastic Surgery Center in Shrewsbury, New Jersey.

23 Dec 2009

Researchers develop new approach for treating and healing skin abscesses

Researchers at the Albert Einstein College of Medicine of Yeshiva University have developed a new approach for treating and healing skin abscesses caused by bacteria resistant to most antibiotics.

23 Dec 2009

UPMC reports 10,000th patient treated using Elekta's Leksell Gamma Knife system

On the morning of December 17, 2009, UPMC physicians used Gamma Knife® surgery to treat the center's 10,000th patient, an 81-year-old male with a tumor deep in his brainstem, a site where traditional surgery would have been impossible. Gamma Knife surgery is performed using Elekta's Leksell Gamma Knife system, which directs up to 201 pencil-thin beams of therapeutic radiation precisely on brain tumors and other targets in the head.

From Elekta 23 Dec 2009

Hospital News and Research

Gene's role in immune system may suggest new treatments for childhood asthma

Scientists use DNA sequence to characterize genome rearrangement in breast cancer samples

New findings show ether discovery might have occurred earlier

Volcano lauds revised guidelines for treating severe coronary artery disease patients

Otsuka America Pharmaceutical joins NPC

TGLN responds to CIHI report on organ donation

Mediware Information Systems introduces new system interface to the U.S. Biovigilance Network

Findings may lead to new methods for diagnosing osteoporosis

New CIHI study highlights that Canada needs to retrieve more organs for transplants

Nationwide Children's Hospital chosen as a BCR for TCGA

Novel discovery offers hope for patients with common brain tumor

Autism study and gene therapy in vision are top scientific achievements in 2009

Beta blockers may increase risk of anemia-induced adverse cardiovascular events

Embryo biopsy safe for singleton pregnancies

ARCA biopharma submits Gencaro trial protocol for review under the FDA’s SPA process

NHLBI grant for identifying genetic and epigenetic causes of human congenital heart disease

Benefits of dispatcher-assisted bystander CPR outweigh potential injury risks

Second successful phrenic nerve decompression surgery

Researchers develop new approach for treating and healing skin abscesses

UPMC reports 10,000th patient treated using Elekta's Leksell Gamma Knife system

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