Embryonic Stem Cells News and Research

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New link between polyamine regulation and ESC biology

A*STAR scientists have for the first time, identified that precise regulation of polyamine levels is critical for embryonic stem cell (ESC) self-renewal - the ability of ESCs to divide indefinitely - and directed differentiation.

2 Mar 2012

New system improves chances of pregnancy during IVF

A novel system for processing embryos during IVF treatment has been shown to significantly improve the chances of pregnancy - by more than a quarter.

1 Mar 2012

Study describes how multiple RNA binding proteins cooperatively control genetic splicing code

Understanding how RNA binding proteins control the genetic splicing code is fundamental to human biology and disease - much like editing film can change a movie scene. Abnormal variations in splicing are often implicated in cancer and genetic neurodegenerative disorders.

17 Feb 2012

Synthetic Oct4 protein more effective at turning genes into pluripotent stem cells

Scientists have found a way to generate and maintain stem cells much more efficiently by amplifying the effect of an essential protein.

17 Feb 2012

U-M's first human embryonic stem cell line to be placed on the U.S.NIH registry

The University of Michigan's first human embryonic stem cell line will be placed on the U.S. National Institutes of Health's registry, making the cells available for federally-funded research. It is the first of the stem cell lines derived at the University of Michigan to be placed on the registry.

15 Feb 2012

Brain tissue created from human skin cells

British scientists have successfully generated brain tissue from human skin. The team has for the first time generated a crucial type of brain cells in the laboratory by reprogramming skin cells. They say it could speed up the hunt for new treatments for conditions such as Alzheimer's disease, epilepsy and stroke.

14 Feb 2012

Third patient dosed in Phase 1/2 SMD trial using RPE cells derived from hESCs

Advanced Cell Technology, Inc., a leader in the field of regenerative medicine, announced today the dosing of third patient in its Phase 1/2 trial for Stargardt's macular dystrophy (SMD) using retinal pigment epithelial (RPE) cells derived from human embryonic stem cells (hESCs).

13 Feb 2012

Parkinson’s disease gene - parkin explored: Study

Researchers at the University at Buffalo have discovered how mutations in the parkin gene cause Parkinson's disease, which afflicts at least 500,000 Americans and for which there is no cure. The results are published in the current issue of Nature Communications.

9 Feb 2012

Komen vice president resigns

Karen Handel says she is leaving immediately so the organization can "refocus" on its mission, after becoming a lightning rod for controversy over its decision to cut funds to Planned Parenthood.

9 Feb 2012

Researchers discover how mutations in parkin gene cause PD

Parkinson's disease researchers at the University at Buffalo have discovered how mutations in the parkin gene cause the disease, which afflicts at least 500,000 Americans and for which there is no cure.

8 Feb 2012

Skin cells converted to brain cells without intermediate stem cell stage

Researchers from California have successfully converted mouse skin cells into cells which develop into the main components of the brain. The experiment, reported in Proceedings of the National Academy of Sciences, is notable because it skipped the middle “stem cell” stage in the process.

2 Feb 2012

Scientists establish HCV infection in liver-like cells derived from iPSCs

Hepatitis C, an infectious disease that can cause inflammation and organ failure, has different effects on different people. But no one is sure why some people are very susceptible to the infection, while others are resistant. Scientists believe that if they could study liver cells from different people in the lab, they could determine how genetic differences produce these varying responses. However, liver cells are difficult to obtain and notoriously difficult to grow in a lab dish because they tend to lose their normal structure and function when removed from the body.

2 Feb 2012

Experts comment on successful stem cell therapy for blindness

According to a new study published in The Lancet, privately funded and led by UCLA and Advanced Cell Technology researchers, two women suffering a progressive form of blindness have shown improved vision.

24 Jan 2012

Stem cells show promise in treating blindness

A medical breakthrough was reported Monday in the journal The Lancet wherein the results of a therapy using human embryonic stem cells in two legally blind patients was described.

24 Jan 2012

Artificial testes being developed to help infertile men produce sperm

Californian researchers are trying to create an artificial testicle that will produce human sperm. Dr. Paul Turek, director of the Turek Clinic in San Francisco, which specializes in male infertility, said the goal is not to create a testicular implant for men, but a “sperm-making biological machine” that will help scientists learn more about just what causes male infertility. “We’re trying to recreate the process of sperm production in a three-dimensional system,” Turek said. “Simple laboratory conditions can’t get it done in humans. Our concept is to actually recreate the testicle itself.”

22 Jan 2012

Converted umbilical cord stem cells hold hope for spinal cord injuries, multiple sclerosis

For the first time ever, stem cells from umbilical cords have been converted into other types of cells, which may eventually lead to new treatment options for spinal cord injuries and multiple sclerosis, among other nervous system diseases.

18 Jan 2012

Researchers produce chimeric monkeys with six distinct genomes

Researchers have produced the world's first chimeric monkeys. The bodies of these monkeys, which are normal and healthy, are composed of a mixture of cells representing as many as six distinct genomes.

6 Jan 2012

New information about how early ESCs develop and form primate species

Newly published research by scientists at Oregon Health & Science University provides significant new information about how early embryonic stem cells develop and take part in formation of the primate species.

6 Jan 2012

Obama and Gingrich differ on embryonic stem cell research

Research!America's new national voter education initiative, Your Candidates-Your Health, features responses from President Obama and Republican Presidential candidate Newt Gingrich on important health research and prevention issues.

28 Dec 2011

Roundup: HIV staff to be cut in Ga.; Abortion news in N.J., Mo.; Wis. Medicaid coverage in limbo

A loss of $3.7 million in federal funds is forcing Georgia to reduce its workforce for HIV prevention. After an inquiry by Georgia Health News, the Department of Public Health this week acknowledged that 20 people in state health districts have been notified they will probably lose their jobs in January, and that an unspecified number of staffers at the department level have received the same notification.

23 Dec 2011