Small Molecules News and Research

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Molecule metabolite variations in breast milk may hold risk factors for childhood obesity

New research suggests the composition of breast milk in normal weight mothers differs from that of overweight mothers, and that variations in small molecule metabolites found in breast milk are possible risk factors for childhood obesity.

11 Apr 2019

Celltrion and iProgen Biotech announce partnership for development of novel ADCs

On April 8, Celltrion and the Canada-based iProgen Biotech Inc. announced to agree to partner for the development of novel ADCs against validated antibody targets, including HER2 and CD20.

8 Apr 2019

Researchers identify crucial player in controlling misfolded proteins

Researchers have identified a protein complex that marks misfolded proteins, stops them from interacting with other proteins in the cell and directs them towards disposal.

27 Mar 2019

Probing Submicron Protein Aggregation using Asymmetrical Flow Field-Flow Fractionation, AF4, and Light Scattering

The most recent developments by Wyatt in their instrumentation and software have made the full potential of FFF accessible to a wider user base. In this interview, Kim R. Williams and Christoph Johann talk to News-Medical and Life Sciences about the technologies and their research.

From Waters | Wyatt Technology 27 Mar 2019

Lian wins ENGINE grant for stem-cell-based therapy to treat Type 1 diabetes

Xiaojun "Lance" Lian, assistant professor of biomedical engineering, was one of three recipients of the College of Engineering's ENGineering for Innovation & Entrepreneurship grant for "Small Molecule-Based Definitive Endoderm Kit and Pancreatic Progenitor Kit for Stem Cell Research and Therapy."

22 Mar 2019

KNAUER introduces new Sepapure FPLC columns and media for protein purification tasks

The new Sepapure columns and media represent high-quality alternatives for common protein purification tasks like size-exclusion, affinity and ion-exchange chromatography.

From KNAUER Wissenschaftliche Geräte GmbH 21 Mar 2019

Researchers discover possible new therapeutic strategy for pancreatic cancer

Researchers from UCLA's Jonsson Comprehensive Cancer Center have identified a possible new therapeutic strategy using two types of drug inhibitors at once to treat one of the world's deadliest cancers.

21 Mar 2019

Age-related changes to gut microbiome have adverse impact on vascular health, study shows

Why do blood vessels naturally stiffen and degrade as we age, boosting cardiovascular disease risk? New University of Colorado Boulder research has identified a surprising new culprit--and it lives in your gut.

20 Mar 2019

New treatment approach could minimize brain damage caused by stroke

In a study published today in the Journal of Experimental Medicine, researchers successfully used a new approach that significantly minimized brain damage caused by stroke in mouse models.

14 Mar 2019

Researchers develop new way to analyze mucus binding

The human body is full of mucus. This viscous goo isn't just a nuisance that gets coughed up or sneezed out -- it can bind to drugs, toxins or microbes, potentially impacting human health. However, relatively little is known about such interactions.

14 Mar 2019

Researchers define pathway that helps us make antibodies

Our bodies are continuously concocting specific antibodies to thwart invaders like a virus or even pollen, and scientists have new information about how the essential production gets fired up and keeps up.

13 Mar 2019

Study uncovers potential new strategy to treat influenza A

A team of researchers from Scripps Research and Janssen Research & Development LLC has discovered an orally active small molecule that neutralizes influenza A group 1 viruses, the most common flu strains.

11 Mar 2019

Research opens up opportunities to unravel the complexity of microbial communities

"Microbial communities run the world," says Jo Handelsman, director of the Wisconsin Institute for Discovery at the University of Wisconsin-Madison.

11 Mar 2019

Newly discovered drug targets could pave way for esophageal cancer therapeutics

Blocking two molecular pathways that send signals inside cancer cells could stave off esophageal adenocarcinoma, the most common esophageal malignancy in the United States, according to new research out of Case Western Reserve University School of Medicine.

28 Feb 2019

Scientists identify how cells make choice between various mechanisms to repair DNA

When DNA in the cell nucleus gets damaged, our cells can resort to a variety of repair mechanisms. A recent study published in 'Nature Cell Biology', to which scientists from Helmholtz Zentrum Muenchen made major contributions, elucidates the molecular basis by which a cell makes the choice between these repair mechanisms.

28 Feb 2019

Novel Imaging Methods for Biomedicine

Wei Min has been awarded the Pittcon 2019 Achievement Award. In this interview, he outlines the current imaging challenges in biomedicine and how his novel chemical imaging methods can overcome these.

From Pittcon 26 Feb 2019

Researchers uncover how Gram-negative bacterium delivers toxins that make us sick

Researchers at Binghamton University, State University of New York have uncovered the unique way in which a type of Gram-negative bacterium delivers the toxins that make us sick. Understanding this mechanism may help design better ways to block and eventually control those toxins.

25 Feb 2019

Study finds out similarity in function between healthy retina cell and tumor cell

How is a healthy retina cell like a tumor cell? It hijacks an energy-producing chemical reaction to churn out molecular building blocks. When tumor cells do it, they use the building blocks to make cancer grow and spread. But when retina cells do it, they renew photoreceptor membranes that keep our vision sharp.

22 Feb 2019

New technique could expedite cancer diagnosis, lead to better patient outcomes

The days - or even weeks - spent waiting for the results of a cancer-screening test can feel like an eternity. Especially when early diagnosis and quick action are tied to better outcomes.

20 Feb 2019

Scientists join forces to identify a new approach to fight African sleeping sickness

Scientists working in a range of disciplines joined forces to identify a new approach to combat African sleeping sickness. Fundamental research undertaken under the supervision of Professor Ute Hellmich of Johannes Gutenberg University Mainz has revealed a promising strategy to develop a suitable agent.