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Importance of the drug Fuzeon (enfuvirtide) in the management of HIV

New potent combinations make suppression of virus to undetectable levels more achievable for treatment-experienced HIV patients.

20 Oct 2005

Diabetes drugs may also prevent nerve degeneration caused by Alzheimer's disease

Recent research has shown a surprising link between Alzheimer’s and diabetes, two of the major health challenges facing society today. According to Dr Holscher modern lifestyle promotes the development of type 2 diabetes, which in turn could drastically increase the number of people to develop Alzheimer’s disease as people with type 2 diabetes are much more likely to develop the disease than healthy people of the same age.

20 Oct 2005

Menin is a key player in the development of some forms of acute leukemia

Tumor-suppressor proteins work to inhibit tumor growth in our bodies and when they win, they spare us a battle with cancer. But one such protein, menin, appears to have a split personality.

20 Oct 2005

Researchers learn to rapidly rebuild immunity in immune-suppressed cancer patients

Patients with multiple myeloma suffer from a malignant proliferation of plasma cells in their bone marrow. The standard treatment for this form of cancer is high-dose chemotherapy and transplantation of one's own blood-producing adult stem cells; however, this aggressive treatment wipes out the mature immune-system cells of patients – leaving them vulnerable to infection.

20 Oct 2005

Hepatitis C linked to illegal blood donation in China

Research in a rural province of central China has documented that illegal blood donation practices led to high hepatitis C virus (HCV) infection rates in blood and plasma donors during the 1980s and early 1990s, and that failure to screen for HCV in transfusion recipients increased their risk of infection as well

20 Oct 2005

Molecule P-glycoprotein (Pgp), may help reduce risk of Alzheimer's

A molecule that has long been an obstacle to cancer chemotherapy and drug treatments for brain disorders may soon become an ally in the fight against Alzheimer's disease, according to researchers at Washington University School of Medicine in St. Louis and the University of Rochester.

20 Oct 2005

Alzheimer disease and the blood brain barrier

Increased production of the amyloid-beta (Abeta) peptide can lead to Abeta aggregation and buildup in the brain and rare familial forms of early onset Alzheimer disease (AD).

20 Oct 2005

Yearly PSA test saves lives

Men who have a yearly blood test to examine their prostate specific antigen levels are nearly three times less likely to die from prostate cancer than those who don't have annual screenings, according to a study presented October 19, 2005, at the American Society for Therapeutic Radiology and Oncology's 47th Annual Meeting in Denver.

19 Oct 2005

Surgery to treat obesity far more risky for men

Researchers say that using stomach-shrinking surgery to treat severe obesity is riskier than previously thought for men, the elderly and people with conditions such as hypertension.

19 Oct 2005

Study of the effects of aripiprazole, olanzapine, quetiapine and risperidone, in elderly patients with dementia

Some newer antipsychotic medications may be associated with a small increased risk of death when used to treat elderly dementia patients, psychiatrists at Johns Hopkins warn.

18 Oct 2005

Drug-eluting stents significantly cut the rates of heart attack and repeat procedures

The use of medicated stents markedly improves the clinical outcomes of patients who develop blockages in aging veins surgically grafted onto the heart, according to a just-published study in the November 2005 issue of Catheterization and Cardiovascular Interventions: Journal of the Society for Cardiovascular Angiography and Interventions.

18 Oct 2005

Yeast cells help show how GSAO (glutathionarsenoxide) angiogenesis inhibitor drug works

The humble yeast has revealed the molecular workings of an anti-cancer drug that stops the growth and spread of tumours in humans by starving their blood supply.

18 Oct 2005

Study demonstrates feasibility of a revolutionary, minimally invasive approach to introducing an electrical lead to stimulate the heart

Correcting the timing of heart contractions through cardiac resynchronization therapy can be a lifesaver for people with advanced heart failure. But the procedure, as it is done today, fails in about 15 percent of patients.

18 Oct 2005

Cutting-edge research to develop this range of next-generation biomedical devices

Revolutionary new self-diagnostic devices to provide early warning of deadly and debilitating illnesses like cancer, diabetes and heart disease are the aim of a Euro 22.5m Science Foundation Ireland research facility to be established at Dublin City University.

18 Oct 2005

Not enough evidence to recommend routine bed rest for hypertension in pregnancy

Currently there is a lack of evidence that keeping pregnant women with high blood pressure in bed for a prolonged period of time improves the chance of a healthy delivery. Prolonged bed rest is disruptive to women's lives, carries the risk of generating blood clots, and may be expensive.

18 Oct 2005

Beta blockers not as effective as other drugs that reduce high blood pressure in patients with hypertension

Beta blockers are not as effective as other drugs that reduce high blood pressure in patients with hypertension, concludes a meta-analysis published online by The Lancet.

18 Oct 2005

Expert evaluates orlistat (Xenical)

A 60 mg low-dose version of the prescription weight-loss medication orlistat (marketed by GlaxoSmithKline as Xenical 120 mg) was found to be safe, effective and tolerable in overweight individuals, according to new data presented today at the 2005 Annual Meeting of NAASO, The Obesity Society in Vancouver, British Columbia.

18 Oct 2005

Discovery increases the yield of stem cells from umbilical cord blood

A team of bioengineers led by the University of Toronto has discovered a way to increase the yield of stem cells from umbilical cord blood, to an extent which could broaden therapeutic use of these cells.

18 Oct 2005

No evidence of a "safe" threshold with environmental toxins

Four of the most widespread environmental toxins - lead, trihalomethanes (found in drinking water), ionizing radiation from indoor radon gas, and tobacco smoke - can cause serious damage to health even at very low levels, say researchers in the open access journal PLoS Medicine.

18 Oct 2005

New prostate cancer test far more accurate

At present in order to predict prostate cancer outcomes, doctors rely on measures that suggest how far the tumour has spread and how abnormal the cancer cells appear under the microscope.

18 Oct 2005

Blood News and Research

Importance of the drug Fuzeon (enfuvirtide) in the management of HIV

Diabetes drugs may also prevent nerve degeneration caused by Alzheimer's disease

Menin is a key player in the development of some forms of acute leukemia

Researchers learn to rapidly rebuild immunity in immune-suppressed cancer patients

Hepatitis C linked to illegal blood donation in China

Molecule P-glycoprotein (Pgp), may help reduce risk of Alzheimer's

Alzheimer disease and the blood brain barrier

Yearly PSA test saves lives

Surgery to treat obesity far more risky for men

Study of the effects of aripiprazole, olanzapine, quetiapine and risperidone, in elderly patients with dementia

Drug-eluting stents significantly cut the rates of heart attack and repeat procedures

Yeast cells help show how GSAO (glutathionarsenoxide) angiogenesis inhibitor drug works

Study demonstrates feasibility of a revolutionary, minimally invasive approach to introducing an electrical lead to stimulate the heart

Cutting-edge research to develop this range of next-generation biomedical devices

Not enough evidence to recommend routine bed rest for hypertension in pregnancy

Beta blockers not as effective as other drugs that reduce high blood pressure in patients with hypertension

Expert evaluates orlistat (Xenical)

Discovery increases the yield of stem cells from umbilical cord blood

No evidence of a "safe" threshold with environmental toxins

New prostate cancer test far more accurate

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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