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Colorectal cancer screening rates are too low

An intervention program designed to promote screening for colorectal cancer – and thereby decrease the number of cancers diagnosed - failed to increase screening rates in the managed care setting, a University of California - Los Angeles study has found.

10 Oct 2005

Actos reduces the combined risk of non-fatal heart attacks, strokes in patients with type-2 diabetes

A study published in The Lancet shows that Takeda's Actos (pioglitazone HCl), an oral glucose lowering medication, significantly reduces the combined risk of non-fatal heart attacks, strokes and deaths by an additional 16% on top of standard medication

10 Oct 2005

Amount of exercise more important than the intensity of the exercise

A study in the October issue of CHEST, the peer-reviewed journal of the American College of Chest Physicians (ACCP), shows that adults who participate in mild exercise, such as walking briskly for 12 miles or exercising for 125 to 200 minutes a week at moderate intensity can significantly improve their aerobic fitness and reduce their risk of cardiovascular disease.

10 Oct 2005

Screening for cardiovascular risk by measuring blood levels of C-reactive protein should not be advocated

C-reactive protein (CRP) is released by the liver in response to inflammation related to an infection, injury, or conditions such as arthritis. Inflammation also has been associated with the cause and progression of cardiovascular disease, particularly in the build up of fatty deposits in the lining of arteries.

10 Oct 2005

Association between long-term smoking and diminished mental proficiency

Smokers often say that smoking a cigarette helps them concentrate and feel more alert. But years of tobacco use may have the opposite effect, dimming the speed and accuracy of a person’s thinking ability and bringing down their IQ, according to a new study led by University of Michigan researchers.

10 Oct 2005

How heat affects people with heart failure

Reduced blood flow to the skin’s surface may be a key cause of heat-related illnesses in patients with congestive heart failure, UT Southwestern Medical Center researchers have found.

10 Oct 2005

The rise of breast cancer

In a continuing increase in breast cancer, one in nine women in the UK now risk contracting the disease during their lifetime.

10 Oct 2005

Tonsils reveal information that helps understand lupus

By snipping out and analyzing tiny samples of patients' tonsils, scientists have identified a key cellular checkpoint that is somehow bypassed in lupus patients, where harmful immune cells that normally are squelched by the body are mistakenly granted access.

9 Oct 2005

Promising new treatment options for prostate cancer

Prostate cancer is the second leading cause of death among American men. It is estimated that one in six males will develop the disease during his lifetime. However, promising new treatment options have been developed to help combat this threatening disease.

9 Oct 2005

Researchers reveal basis for hereditary coproporphyria

A research team led by scientists at The University of Texas Medical School at Houston has determined the structure of an enzyme that when defective causes an inherited disease that afflicts sufferers with severe abdominal pain, psychiatric symptoms, skin fragility, and light sensitivity.

9 Oct 2005

New technique to produce large numbers of antibodies quickly

Faster method to create antibodies for disease research British scientists are pioneering a new technique to produce large numbers of antibodies quickly and reliably to help the study of dangerous bacteria.

9 Oct 2005

Obese Zucker rat model shares the symptoms of obesity with a growing number of Americans

A mutant rat that mimics a 400-pound human is helping scientists understand early vascular changes that make walking a pain for more than 2 million Americans.

9 Oct 2005

Patients in level I trauma centers were nearly 20 percent less likely to die than those in level II centers

Patients who are taken to a level 2 trauma center after suffering serious injury are significantly more likely to die than comparable patients treated at a major level 1 trauma center, according to researchers at the Keck School of Medicine of the University of Southern California.

9 Oct 2005

Recommendation that physicians be a little more cautious in deciding against tPA treatment

Although use of the clot-dissolving drug tissue plasminogen activator (tPA) has revolutionized the treatment of acute stroke patients, many of those who could receive the drug do not because their initial symptoms appear mild or improve soon after they arrive at the hospital.

9 Oct 2005

New data demonstrates how CA4P has anti-tumor and anti-angiogenic activity

Anti-angiogenic agents have been successful in the clinic for blocking the growth of solid tumors. However, these agents used in combination with chemotherapy have improved the survival of patients with cancers by only several months.

9 Oct 2005

Gut antibody could prove to be a promising drug target for Crohn's disease

A collaboration led by the Burnham Institute for Medical Research has found that an antibody which binds to an unusual sugar molecule residing in the gut halts the inflammation seen in Crohn's disease and other intestinal inflammations. The antibody could prove to be a promising drug target for these common chronic intestinal disorders.

9 Oct 2005

New information regarding the genetic, cellular and neurological bases of susceptibility to autism and schizophrenia

Two New Jersey research teams are reporting discoveries about the biological nature of psychiatric disorders that may bring them closer to the ultimate goal of finding cures for complex diseases, such as autism and schizophrenia.

9 Oct 2005

Avian influenza and the U.S

If a virulent strain of avian influenza ever struck the U.S. poultry industry, this country probably would fare better than many other nations due to careful biosecurity procedures in force.

9 Oct 2005

New role for the blood protein serum amyloid P in the body's response to medical materials

Using a technique called proteomics, the researchers identified many of the blood proteins that stick (adsorb) to the surfaces of medical devices. Blood proteins that adsorb to the surfaces of materials unfold and can be recognized by the body, which then mounts a response against the device.

5 Oct 2005

Fruits and vegetables can increase or decrease the activity and toxicity of orally-administered drugs

Eating fruits and vegetables is essential to living a long and healthy life, yet research has shown they can cause dangerous interactions with medicines.

5 Oct 2005

Blood News and Research

Colorectal cancer screening rates are too low

Actos reduces the combined risk of non-fatal heart attacks, strokes in patients with type-2 diabetes

Amount of exercise more important than the intensity of the exercise

Screening for cardiovascular risk by measuring blood levels of C-reactive protein should not be advocated

Association between long-term smoking and diminished mental proficiency

How heat affects people with heart failure

The rise of breast cancer

Tonsils reveal information that helps understand lupus

Promising new treatment options for prostate cancer

Researchers reveal basis for hereditary coproporphyria

New technique to produce large numbers of antibodies quickly

Obese Zucker rat model shares the symptoms of obesity with a growing number of Americans

Patients in level I trauma centers were nearly 20 percent less likely to die than those in level II centers

Recommendation that physicians be a little more cautious in deciding against tPA treatment

New data demonstrates how CA4P has anti-tumor and anti-angiogenic activity

Gut antibody could prove to be a promising drug target for Crohn's disease

New information regarding the genetic, cellular and neurological bases of susceptibility to autism and schizophrenia

Avian influenza and the U.S

New role for the blood protein serum amyloid P in the body's response to medical materials

Fruits and vegetables can increase or decrease the activity and toxicity of orally-administered drugs

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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