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GRK5 protein plays important role in hypertension

Researchers at Jefferson Medical College have implicated a protein called GRK5 as having an important role behind essential hypertension, which affects more than 65 million Americans.

5 Oct 2005

Possible vaccine to protect newborns from fatal bacteria Group B Streptococcus

Microbiologists from the University of Bradford believe they may be closer to developing a vaccine that can protect newborn babies from being infected by the common and potentially fatal bacteria Group B Streptococcus.

5 Oct 2005

To improve the diets of British children we need to look beyond school dinners

The health of pupils eating school dinners is no worse - and in some respects may be better - than that of pupils eating meals provided from home, concludes a study published online by the British Medical Journal today.

5 Oct 2005

PACs should not be used routinely in patients in intensive care units with severe heart failure

The use of a pulmonary artery catheter (PAC) -- a device used for more than 30 years to assess cardiovascular health and to help guide the treatment of critically ill patients -- does not appear to improve outcomes nor confer added risks to patients.

4 Oct 2005

Amiloride and spironolactone may help patients with high blood pressure

Two inexpensive but widely overlooked drugs may help many patients who continue to have high blood pressure despite taking standard blood pressure medications, according to research by Indiana University School of Medicine scientists.

4 Oct 2005

High blood glucose levels early in pregnancy deprive the embryo of oxygen

The babies of women with diabetes are two to five times more likely to develop birth defects than offspring of women without the disease.

4 Oct 2005

Divalent metal transporter-1 decreases metal-related injury in the lung

Multi-vitamin products, nutritional supplements and parents tout the need for such mineral elements as calcium, zinc, phosphorus, iron and others.

4 Oct 2005

Effects of anticonvulsants on women

The Epilepsy Foundation has issued a Call to Action to women of childbearing age who take anticonvulsant medications for conditions that include epilepsy, migraine headaches, and certain psychiatric disorders, urging them to talk to their healthcare providers about treatment options.

4 Oct 2005

Kidney paired donation transplantation has graft survival rates equivalent to compatible live donor transplants

A preliminary study suggests that kidney paired donation transplantation, in which incompatible donor/recipient pairs exchange kidneys so that each recipient receives a compatible kidney, had graft survival rates equivalent to compatible live donor transplants, according to a study in the October 5 issue of JAMA: The Journal of the American Medical Association.

4 Oct 2005

Hospitalized patients with severe congestive heart failure did not experience a benefit from use of pulmonary artery catheterization

Advances in medical therapy have improved outcomes for many ambulatory patients with heart failure and low ejection fraction (EF; a measure of how much blood the left ventricle of the heart pumps out with each contraction), according to background information in the article.

4 Oct 2005

Evaluation of the efficacy of buprenorphine hydrochloride and clonidine hydrochloride, in detoxification of opioid-dependent teenagers

In a comparison of two drugs prescribed to treat teenagers dependent on heroin and other opioids, the drug buprenorphine was more effective, especially in treatment retention, according to a study in the October issue of Archives of General Psychiatry.

4 Oct 2005

Discovery of molecular roots of asthma, arthritis, and multiple sclerosis

The molecular roots of inflammatory and autoimmune diseases such as asthma, arthritis, and multiple sclerosis (MS) have been discovered by a team of researchers led by The University of Texas M. D. Anderson Cancer Center. They say their findings may point to ways to effectively treat these diseases - if not stop them before they start.

4 Oct 2005

Study paves the way for new therapeutic targets which can potentially improve heart disease in patients with end-stage kidney failure

Night-time hemodialysis patients may have a greater capacity to repair their hearts and blood vessels compared to those on conventional dialysis three times a week, according to a study in the October issue of the American Journal of Physiology - Renal Physiology, published by the American Physiological Society.

4 Oct 2005

Rapid weight gain between the ages of 25 and 40 doubles likelihood of prostate cancer recurrence

Men who gain weight rapidly between the ages of 25 and 40 are twice as likely to have recurrence of prostate cancer after surgery as men without rapid rates of weight gain, researchers from University of Texas M. D. Anderson Cancer Center reported in the October 1 issue of "Clinical Cancer Research."

4 Oct 2005

New digital angiography flat panel system reduces the radiation dose to patients undergoing interventional treatment for liver cancer

The study compared the radiation dose to patient's skin during transcatheter arterial embolization, a procedure that blocks the flow of a blood to a tumor. Doses were assessed for 12 patients using a new angiography unit with a digital flat-panel system and 12 using a conventional unit for angiographic imaging.

4 Oct 2005

Role of asymmetric dimethylarginine in damaged blood vessels

A substance found naturally in the blood vessel lining is thought to contribute towards diseases associated with the circulation system, such as heart failure, high blood pressure, stroke and kidney disease.

4 Oct 2005

Protein secreted by the dog hookworm may advance vaccine development in humans

A paper published in this week's PLoS Medicine shows that vaccination against a protein secreted by the dog hookworm can protect against blood loss and anaemia caused by the same hookworm in dogs.

4 Oct 2005

Gleevec's uses might expand even further

Gleevec (Imatinib) is a representative of the newest generation of cancer drugs. The substance conveys its potent anti-proliferative effect by selectively supressing the tyrosine kinase pathway. The Giessen lung researchers now issue a first report of this substance as a new target therapy for pulmonary hypertension

4 Oct 2005

Johns Hopkins awarded $12 million to study how stem cell therapies can be used to treat hearts damaged by heart attack

Heart specialists at Johns Hopkins Heart Institute have been awarded more than $12 million from the National Heart, Lung, and Blood Institute (NHLBI) to study how stem cell therapies can be used to treat hearts damaged by heart attack or heart failure.

4 Oct 2005

United States has a major weight problem and it will get worse

A large, community-based study -- considered the first study to assess the long-term risk of developing overweight and obesity in adults -- found that over 30 years, nine out of 10 men and seven out of 10 women were overweight or became overweight. In addition, more than one in three were obese or became obese.

4 Oct 2005

Blood News and Research

GRK5 protein plays important role in hypertension

Possible vaccine to protect newborns from fatal bacteria Group B Streptococcus

To improve the diets of British children we need to look beyond school dinners

PACs should not be used routinely in patients in intensive care units with severe heart failure

Amiloride and spironolactone may help patients with high blood pressure

High blood glucose levels early in pregnancy deprive the embryo of oxygen

Divalent metal transporter-1 decreases metal-related injury in the lung

Effects of anticonvulsants on women

Kidney paired donation transplantation has graft survival rates equivalent to compatible live donor transplants

Hospitalized patients with severe congestive heart failure did not experience a benefit from use of pulmonary artery catheterization

Evaluation of the efficacy of buprenorphine hydrochloride and clonidine hydrochloride, in detoxification of opioid-dependent teenagers

Discovery of molecular roots of asthma, arthritis, and multiple sclerosis

Study paves the way for new therapeutic targets which can potentially improve heart disease in patients with end-stage kidney failure

Rapid weight gain between the ages of 25 and 40 doubles likelihood of prostate cancer recurrence

New digital angiography flat panel system reduces the radiation dose to patients undergoing interventional treatment for liver cancer

Role of asymmetric dimethylarginine in damaged blood vessels

Protein secreted by the dog hookworm may advance vaccine development in humans

Gleevec's uses might expand even further

Johns Hopkins awarded $12 million to study how stem cell therapies can be used to treat hearts damaged by heart attack

United States has a major weight problem and it will get worse

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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