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Antibody in humans that quickly fights the smallpox virus

Researchers at the La Jolla Institute for Allergy & Immunology (LIAI) have made a major advancement toward protecting society against a smallpox outbreak by identifying an antibody in humans that quickly fights the smallpox virus.

26 Sep 2005

Loss of body mass over time appears to be strongly linked to older adults' risk of developing Alzheimer's disease

The findings are the first to associate decline in body mass index (BMI) with the eventual onset of AD. The researchers suggest that the loss of body mass reflects disease processes and that change in BMI might be a clinical predictor of the development of AD.

26 Sep 2005

Testing for drug resistance in HIV-infected patients at the time of diagnosis may increase patients' life expectancy

Resistance to antiretroviral therapy, even in patients who have never received treatment, is a growing concern. However, genotype resistance testing, which involves looking for the presence of resistance genes, is not a standard procedure at the time a patient is diagnosed with HIV, probably due to lack of data on its benefits and its relatively high cost compared with other routine blood tests.

26 Sep 2005

$Statin use associated with a 36 percent reduction in risk of fracture$

Statin use associated with a 36 percent reduction in risk of fracture

In a large study of elderly, predominately male veterans, statin use was associated with a 36 percent reduction in risk of fracture when compared with no lipid-lowering therapy, according to a study in the Archives of Internal Medicine

26 Sep 2005

Researchers gain insights into how malaria pathogen destroys the cells in which it resides

By specially tagging the outer and inner membranes of red blood cells infected with the malaria parasite and tracking the cellular changes that precede the cell bursting event that disperses parasites to other blood cells, a group of researchers has deepened our understanding of how the malaria pathogen destroys the cells in which it resides.

26 Sep 2005

Innovative new treatment for moderate to severe heart failure

Cardiologists at Beth Israel Medical Center are currently enrolling patients in an investigational study that is looking at the safety and efficacy of an innovative new treatment for moderate to severe heart failure, in which a unique pacemaker-like device helps strengthen the heart's pumping power

26 Sep 2005

Tests of cognitive function are the best way so far to predict whether healthy elderly people will develop Alzheimer's

Although Alzheimer's disease begins long before symptoms appear, early diagnosis of Alzheimer's has so far been elusive. And given that there is no cure for the disease, benefits of early detection remain questionable.

26 Sep 2005

Surprising immune system cells discovery

Immune system cells are connected to each other by an extensive network of tiny tunnels that, like a building's hidden pneumatic tube system, are used to shoot signals to distant cells.

26 Sep 2005

Folate may protect against cognitive decline in older adults

According to a recent report in the American Journal of Clinical Nutrition, folate, a B vitamin found in foods like leafy green vegetables and citrus fruit, may protect against cognitive decline in older adults.

26 Sep 2005

Aggressive public health efforts to control hypertension may help preserve cognitive abilities as well as cardiovascular health

Not only does high blood pressure adversely affect mental functioning, but the correlation appears to be stronger among African-Americans than among whites, researchers report in the current issue of Psychosomatic Medicine.

26 Sep 2005

Researchers map genetic location that explains why certain blood pressure-lowering drugs aren't effective for some people

"The findings bring us a step closer to developing targeted therapies for patients with high blood pressure who might otherwise be started on medications that won't help," said lead author Sandosh Padmanabhan, Ph.D.

26 Sep 2005

Lead exposures early in life combined with high blood pressure in working age adults may lead to diminishing cognitive abilities in later life

Exposure to lead in early childhood and adolescence may contribute to hypertension-related decline that can impair a person's cognitive abilities, according to a new study presented at the 2005 American Heart Association's High Blood Pressure Research meeting.

26 Sep 2005

Genes from both the mother and father can trigger pre-eclampsia

Pre-eclampsia is a serious condition where abnormally high blood pressure and other disturbances develop in the second half of pregnancy. It occurs in 3-5% of pregnancies and is dangerous for both mother and child.

26 Sep 2005

Abnormal leakage of lymph fluid from the ruptured lymphatic vessels stimulates the accumulation of fat

Leaky lymphatic vessels are the leading cause of the adult onset obesity observed in a laboratory model developed by investigators at St. Jude Children's Research Hospital.

26 Sep 2005

Smoking may increase the risk of developing diabetes

The surprising finding emerged when researchers examined the relationship between smoking and diabetes among participants in a major national study, the Insulin Resistance Atherosclerosis Study (IRAS).

26 Sep 2005

"Designer" rats help show how declining estrogen after menopause can affect hypertension

Scientists at Wake Forest University School of Medicine have created a better research rat – the first to enable them to study how declining estrogen after menopause can affect hypertension, heart failure and kidney damage.

26 Sep 2005

New approach to treating brain aneurysm combining the use of intracranial stents and coil embolization

A fender-bender may have saved Douglas Collins' life. A CT scan following the accident discovered Collins, 64, had a brain aneurysm, a weakness in the arterial wall that if ruptured could cause a stroke or death. It was not caused by the accident, but likely could have been a ticking time bomb present for years. The aneurysm was large and previously thought to require open surgery and a lengthy recovery.

26 Sep 2005

Research highlights the role of viral sequence analysis in improving our overall understanding of hepatitis A cases in the U.S.

Novel use of genetic testing methods helped public health officials control and limit the further spread of four outbreaks of foodborne hepatitis A virus in 2003 related to the consumption of green onions, according to a detailed analysis published in the October 15 issue of The Journal of Infectious Diseases, now available online.

26 Sep 2005

Link between ambient air pollution and acute myocardial infarction, or heart attack

An article published in the Journal of Thrombosis and Haemostasis looks specifically at airborne particulate matter resulting mainly from the combustion of fuel, including coal and also from forest fires.

26 Sep 2005

Israeli scientists successfully transplant ovaries in sheep and trigger early embryonic development

Israeli scientists report in Human Reproduction that they have successfully transplanted whole frozen and thawed ovaries in sheep, retrieved oocytes from these ovaries and triggered them in the laboratory into early embryonic development.

26 Sep 2005

Blood News and Research

Antibody in humans that quickly fights the smallpox virus

Loss of body mass over time appears to be strongly linked to older adults' risk of developing Alzheimer's disease

Testing for drug resistance in HIV-infected patients at the time of diagnosis may increase patients' life expectancy

Statin use associated with a 36 percent reduction in risk of fracture

Researchers gain insights into how malaria pathogen destroys the cells in which it resides

Innovative new treatment for moderate to severe heart failure

Tests of cognitive function are the best way so far to predict whether healthy elderly people will develop Alzheimer's

Surprising immune system cells discovery

Folate may protect against cognitive decline in older adults

Aggressive public health efforts to control hypertension may help preserve cognitive abilities as well as cardiovascular health

Researchers map genetic location that explains why certain blood pressure-lowering drugs aren't effective for some people

Lead exposures early in life combined with high blood pressure in working age adults may lead to diminishing cognitive abilities in later life

Genes from both the mother and father can trigger pre-eclampsia

Abnormal leakage of lymph fluid from the ruptured lymphatic vessels stimulates the accumulation of fat

Smoking may increase the risk of developing diabetes

"Designer" rats help show how declining estrogen after menopause can affect hypertension

New approach to treating brain aneurysm combining the use of intracranial stents and coil embolization

Research highlights the role of viral sequence analysis in improving our overall understanding of hepatitis A cases in the U.S.

Link between ambient air pollution and acute myocardial infarction, or heart attack

Israeli scientists successfully transplant ovaries in sheep and trigger early embryonic development

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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