Immune System News and Research

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Novel antibodies could provide a universal flu vaccine

Now, a new study published in the journal Science on October 25, 2019, reports on a set of three novel antibodies that bind to another type of viral cell surface antigen called neuraminidase (NA) that is necessary for viral replication.

28 Oct 2019

New cellular immunotherapy for cancers

A new study published in the journal Nature Communications on 22 October 2019 reports a new approach to cancer treatment that increases the immune capability of T lymphocytes against malignant cancers. This allows the T cells to successfully infiltrate and destroy these tumors. Animal trials have been completed and the researchers are planning clinical trials in human beings next.

26 Oct 2019

Phase 2 clinical trial of CAR T-cell therapy starts at Atlantic Health System

Atlantic Health System is treating patients in a new Phase 2 clinical trial of CAR T-cell therapy at Morristown Medical Center. A select number of sites across the U.S. are involved in this study, which is done on an outpatient basis.

25 Oct 2019

White and brown fat cells send very different signals to rest of the body

Many people might not realize that they have different types of body fat. Most of it is white fat that sits on your stomach, hips and thighs, for example. White fat is an energy storage that our body can use when food is scarce.

25 Oct 2019

Study finds molecular key to formation of mature and fully functioning T cells

In a finding that could help lead to new therapies for immune diseases like multiple sclerosis and IBD, scientists report in the Journal of Experimental Medicine identifying a gene and family of proteins critical to the formation of mature and fully functioning T cells in the immune system.

25 Oct 2019

New nanoenzyme may help increase anti-tumor immunity

Theoretically, our immune system could detect and kill cancer cells. Unfortunately, tumors are well armed to fight these attacks. Despite modern cancer treatments, metastases and relapses remain a major problem.

25 Oct 2019

Researchers find antibody that may protect against wide range of lethal influenza viruses

A nationwide team of researchers has found an antibody that protects mice against a wide range of potentially lethal influenza viruses, advancing efforts to design of a universal vaccine that could either treat or protect people against all strains of the virus.

25 Oct 2019

TB is not a life-long infection in most people

A new analysis challenges the longstanding notion that tuberculous infection is a life-long infection that could strike at any time and cause tuberculosis. Based on a review of clinical studies, researchers from the Perelman School of Medicine at the University of Pennsylvania and colleagues show that people who test positive with immunologic TB skin or blood tests rarely develop TB.

25 Oct 2019

UAB physicians encourage everyone to get a flu shot between October and early November

The change of season in October and November brings in crisp, fall weather for the majority of the United States. Many begin to look toward the holiday season to come, but few think about the impending cold weather and subsequent sickness that pops up when winter arrives.

25 Oct 2019

Scientists pinpoint epigenetic differences in the way lupus affects black women

Scientists at the HudsonAlpha Institute for Biotechnology have pinpointed epigenetic differences in the way lupus affects black women compared to other lupus patients, revealing important mechanics of the puzzling disease.

24 Oct 2019

Ultraviolet B light is good for the gut microbiome

A small study published in the journal Frontiers in Immunologyon October 24, 2019, shows that exposure to ultraviolet B (UVB) light, which is commonly achieved through sunlight exposure, can trigger specific beneficial changes in the gut microbiome, which are dependent on the preceding serum levels of vitamin D.

24 Oct 2019

Gut microbiome is a reality in fetal life also

A study published in the Journal of Clinical Investigation shows that in both mice and humans, the fetal gut has its own microbiome, which is probably derived straight from the maternal organism.

24 Oct 2019

Flu antibody could be a key to better treatments for severe flu disease

Researchers have found an antibody that protects mice against a wide range of lethal influenza viruses, according to a study from Washington University School of Medicine in St. Louis, Icahn School of Medicine at Mount Sinai in New York City, and Scripps Research in La Jolla, Calif.

24 Oct 2019

Protein mutation that causes inflammatory bowel diseases becomes dysfunctional

A new study led by researchers at St. Michael's Hospital and the Princess Margaret Cancer Centre in Canada and Zhejiang University School of Medicine in China has uncovered why a protein mutation that causes inflammatory bowel diseases is dysfunctional.

24 Oct 2019

How does cancer look on day 1? Researchers collaborate to find out

Researchers from Britain and United States are working in collaboration to detect the earliest possible sign of cancer within the body and trace the alterations that lead to full blown cancer. This may help doctors detect cancer even before it is fully formed, the researchers hope.

24 Oct 2019

Study opens up array of options for developing treatments for cancer or autoimmune disorder

Immunologists at St. Jude Children's Research Hospital have discovered key biological switches that control regulatory T cells--specialized white blood cells that keep the immune system in check.

24 Oct 2019

NIAID-supported clinical trial begins at four Vaccine and Treatment Evaluation Units

A clinical trial in which healthy adults will be deliberately infected with influenza virus under carefully controlled conditions is recruiting volunteers at four Vaccine and Treatment Evaluation Units (VTEUs) supported by NIH's National Institute of Allergy and Infectious Diseases.

24 Oct 2019

Universal influenza vaccine developed at Cornell is set for human clinical trials

A universal influenza vaccine with the potential to be longer lasting and more effective than commercially available vaccines is destined for human clinical trials, thanks to a $17.9 million grant from the National Institute of Allergy and Infectious Diseases.

24 Oct 2019

ConvertibleCAR immunotherapy can be used to attack HIV latent reservoir

A team of Gladstone scientists and their partners at Xyphos Biosciences, Inc. describe a new way of attacking cells infected by HIV in this week's issue of the journal Cell.

24 Oct 2019

Researchers discover unexpected role of mTORC2 protein in colorectal cancer

New results from researchers at MedUni Vienna's Center for Pathobiochemistry and Genetics show that a protein called mTORC2, which is the target of newly developed cancer drugs, is not even active in colorectal cancer. mTORC2 activity was only found in certain immune cells, which actually need this protein to fight cancer cells.

24 Oct 2019