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Molecular signatures reveal why women are more likely to die from glioblastoma

Scientists have discovered molecular signatures that reveal why women are more likely to develop and die from the brain cancer, glioblastoma.

2 Jan 2019

Study uncovers how tumors backfire on neoadjuvant chemotherapy

Some patients with breast cancer receive chemotherapy before the tumor is removed with surgery. This approach, called 'neoadjuvant' therapy, helps to reduce the size of the tumor to facilitate breast-conserving surgery, and can even eradicate the tumor, leaving few or no cancerous cells for the surgeon to remove.

2 Jan 2019

Patients with stage IV disease now living a median 6.8 years after ALK+ NSCLC diagnosis

According to the National Cancer Institute, patients diagnosed with non-small cell lung cancer (NSCLC) between the years 1995 and 2001 had 15 percent chance of being alive 5 years later. For patients with stage IV disease, describing cancer that has spread to distant sites beyond the original tumor, that statistic drops to 2 percent.

2 Jan 2019

Review of recent advances in label-free quantification in cancer proteomics

In recent years, proteomics research has become a popular method for characterizing the functional proteins driving the transformation of malignancy, tracing the large-scale protein alterations induced by anti-cancer drug, as well as discovering the innovative targets and first-in-class drugs for oncologic disorders.

28 Dec 2018

Scientists move one step closer towards treatment for low-grade gliomas with SYNODOS

Treatment for low-grade gliomas in patients living with neurofibromatosis type 1 are now one step closer thanks to recent research discoveries initiated and funded by the Children's Tumor Foundation.

28 Dec 2018

Kanazawa University researchers unravel link between inflammation and cancer

Severe inflammation in tissues is often associated with the occurrence of cancer. The mechanism linking both these conditions is not clearly understood. Furthermore, inflamed and cancerous tissues contain a heterogenous mix of damaged and protective cells.

27 Dec 2018

New method of cancer stem cells activation to destroy tumors

This risky method of anti-cancer therapy was suggested by scientists of Far Eastern Federal University (FEFU). Their review of mechanisms for molecular activation of stem cells of gliomas (most widely-spread brain tumors) was approved for publishing in the Frontiers in Cellular Neuroscience journal.

26 Dec 2018

CWRU researcher receives nearly $1 million to study drug resistance mechanisms in prostate cancer

Sanjay Gupta, PhD, of Case Western Reserve University School of Medicine and University Hospitals Cleveland Medical Center will receive $962,000 over three years to investigate drug resistance mechanisms in prostate cancer.

24 Dec 2018

Study reveals how molecular mechanisms regulate lysosomal exocytosis by phagocytes

Lysosomes are filled with more than 50 different hydrolytic enzymes, which are capable of digesting most cellular components.

23 Dec 2018

New bacteria-based drug delivery system could radically expand cancer treatment options

An interdisciplinary team of three Virginia Tech faculty members affiliated with the Macromolecules Innovation Institute has created a drug delivery system that could radically expand cancer treatment options.

21 Dec 2018

New research examines cancer metabolism at multiple scales

No matter what form cancer takes in the body, it starts at the cellular level and grows via metabolism run amok.

21 Dec 2018

New portable optical imaging system brings diagnostic potential into operating room

A team of University of Illinois at Urbana-Champaign researchers led by Professor Stephen Boppart has successfully visualized the tumor microenvironment of human breast tissue shortly after it was surgically removed from a patient in the operating room.

20 Dec 2018

Researchers find new way to cut the power of tumors

Instead of tackling tumors head-on, an international team of researchers from the University of Geneva and the Amsterdam UMC, location VUmc in Amsterdam has chosen to regulate their vascularization by intervening with cellular receptor that is overexpressed specifically in cancer blood vessels.

20 Dec 2018

Scientists investigate potential of nanomaterials to activate the body's antitumor immune response

The importance of research into the role of the immune system in the development and therapy of oncological diseases was emphasized by the Royal Swedish Academy, which recently named James Allison and Tasuku Honjo recipients of the 2018 Nobel Prize in Physiology or Medicine for launching an effective new way to attack cancer by treating the immune system rather than the tumor.

20 Dec 2018

HPV discovery could lead to new treatments for cervical cancer

Researchers at the University of Virginia School of Medicine have made a discovery about human papillomavirus that could lead to new treatments for cervical cancer and other cancers caused by the virus.

19 Dec 2018

Horizon Discovery partners with C4XD to validate novel synthetic lethal oncology targets

Horizon Discovery Group today announces that it has entered into an exclusive target discovery partnership with C4XD, a pioneering drug discovery company.

From Revvity 19 Dec 2018

Looking outside the tumor and thinking outside the box to diagnose lung cancer

Scientists in Anant Madabhushi's computational imaging lab at Case Western Reserve University have started thinking outside the box--or in their case, looking outside the tumor.

19 Dec 2018

Black men diagnosed with low-grade prostate cancer have higher risk of death, study shows

Black men diagnosed with prostate cancer classified as low risk may actually have a more-aggressive form of the disease that is more likely to be fatal than in nonblack men placed in the same prognostic category, a new study suggests.

18 Dec 2018

Combination of a vaccine and checkpoint drugs reduces pancreatic tumors in mice

Researchers at the Johns Hopkins Kimmel Cancer Center discovered a combination of a cancer vaccine with two checkpoint drugs reduced pancreatic cancer tumors in mice, demonstrating a possible pathway for treatment of people with pancreatic cancers whose response to standard immunotherapy is poor.

18 Dec 2018

Researchers discover how MAPK translocation leads to drug resistance in melanoma

Researchers have discovered that the ER translocation of MAPK leads to drug resistance in melanoma.

18 Dec 2018

Tumor News and Research

Molecular signatures reveal why women are more likely to die from glioblastoma

Study uncovers how tumors backfire on neoadjuvant chemotherapy

Patients with stage IV disease now living a median 6.8 years after ALK+ NSCLC diagnosis

Review of recent advances in label-free quantification in cancer proteomics

Scientists move one step closer towards treatment for low-grade gliomas with SYNODOS

Kanazawa University researchers unravel link between inflammation and cancer

New method of cancer stem cells activation to destroy tumors

CWRU researcher receives nearly $1 million to study drug resistance mechanisms in prostate cancer

Study reveals how molecular mechanisms regulate lysosomal exocytosis by phagocytes

New bacteria-based drug delivery system could radically expand cancer treatment options

New research examines cancer metabolism at multiple scales

New portable optical imaging system brings diagnostic potential into operating room

Researchers find new way to cut the power of tumors

Scientists investigate potential of nanomaterials to activate the body's antitumor immune response

HPV discovery could lead to new treatments for cervical cancer

Horizon Discovery partners with C4XD to validate novel synthetic lethal oncology targets

Looking outside the tumor and thinking outside the box to diagnose lung cancer

Black men diagnosed with low-grade prostate cancer have higher risk of death, study shows

Combination of a vaccine and checkpoint drugs reduces pancreatic tumors in mice

Researchers discover how MAPK translocation leads to drug resistance in melanoma

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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