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When it comes to inflammation, too much of a good thing can be deadly

In some severely injured patients, this normal healing process can develop into a lethal, whole-body response, including bloodstream infection (sepsis) and multiple organ failure. How and why inflammation turns from healing to harming is still mysterious, so doctors can't accurately predict how each injured patient will fare.

31 Aug 2005

U.S. to toughen mad cow safeguards after case in Texas

The U.S. Agriculture Department (USDA) has now formally closed its investigation of the first native U.S. case of mad cow disease, in June this year.

31 Aug 2005

Early life exposure to second-hand smoke can produce life-long respiratory problems

A new study finds early life exposure to second-hand smoke can produce life-long respiratory problems. The study of 35,000 adult non-smokers in Singapore found that those who lived with a smoker during childhood had more respiratory problems, including chronic cough.

30 Aug 2005

Carbohydrate known as OGT2378 inhibits tumor growth

A non-toxic chemical compound that prevents cancer cells from producing a critical membrane component has been shown to suppress tumor growth and tumor size in mice without unwanted side effects, according to researchers at the Children’s National Medical Center in Washington, D.C.

30 Aug 2005

Danish scientists have identified which head and neck cancer patients will benefit from additional drug treatment during radiotherapy

Tumours that have low concentrations of oxygen (hypoxia) are resistant to radiotherapy. A drug called nimorazole (a hypoxia radiosensitiser) can improve the outcome of radiotherapy for patients with these types of tumours. However, at the moment there is no way to identify people with tumours that lack oxygen, who need this additional drug treatment, from those that only need radiotherapy.

30 Aug 2005

Simple new way to modify collagen, paving the way for better infection-fighting bandages

Collagen often pops up in beauty products and supermodel lips. But by mating collagen with a molecular hitchhiker, materials scientists at Johns Hopkins hope to create some important medical advances.

30 Aug 2005

When it comes to heart bypass surgery, women twice as likely to die

According to a new study when it comes to heart bypass surgery, women are nearly twice as likely as men to die from complications.

30 Aug 2005

Designer molecules that combine metals such as copper with natural organic materials could treat diseases in the body

That's the finding of chemists at Ohio State University, who have successfully tested such molecules against portions of HIV and Hepatitis C virus RNA in the laboratory. They've also created molecules that act like ACE, or angiotensin-converting enzyme, inhibitors - drugs that are used to lower blood pressure.

30 Aug 2005

Viagra fights heart and lung diseases

German researchers have reported on the impact of Viagra on pulmonary hypertension at the Frontiers of Vascular Medicine Conference at Monash University this week.

30 Aug 2005

Teenage drug use can lead to adult addiction and heart attack

A new study from the Howard Florey Institute in Melbourne may help explain why people who experimented with amphetamines, such as 'speed', as teenagers are more likely to become addicted and more susceptible to heart attack following re-use of the drug as adults.

30 Aug 2005

Blood flow into the brain may play a larger role in the development of dementia than previously believed

Researchers from Leiden University Medical Center in the Netherlands used magnetic resonance imaging (MRI) to examine the brains of elderly patients with and without dementia related to Alzheimer's or Parkinson's disease.

30 Aug 2005

Aspirin shown to be beneficial before heart surgery

Surgeons who have been advising their patients to avoid taking aspirin in the days before surgery because they feared it could cause bleeding, will be reassured by the results of a new study.

30 Aug 2005

Statins reduce heart attack deaths by 50%

According to a U.S. study, giving a heart attack patient a statin drug as soon as possible reduces the chance he or she will die by 50 percent.

30 Aug 2005

If you thought getting mugged was more likely than a stroke - wrong again!

A new survey suggests that the risk of having a stroke is greatly underestimated by most people in the UK.

30 Aug 2005

Dental problems caused by radiation, chemotherapy should be treated before a child undergoes immunosuppression as part of bone marrow transplantation therapy

Many children who undergo bone marrow transplantation (BMT) as part of cancer treatment already have dental abnormalities that leave them vulnerable to potentially life-threatening bacterial infections, according to investigators at St. Jude Children's Research Hospital. A report on this study appears in the prepublication online edition of Bone Marrow Transplantation.

29 Aug 2005

Three-dimensional molecular structure of a promising malaria-vaccine component

An international team of scientists that includes a researcher from the U.S. Department of Energy's Brookhaven National Laboratory has determined the three-dimensional molecular structure of a promising malaria-vaccine component.

29 Aug 2005

Relative of the celebrated COX-2 inhibitor celecoxib is tough tumor fighter

A close structural relative of the celebrated COX-2 inhibitor celecoxib (brand name: Celebrex) is a potent tumor fighter, able to wipe out tumor cells that are resistant to conventional chemotherapies, according to an interdisciplinary team of researchers from the University of Southern California.

29 Aug 2005

Vitamin D puts a brake on activated macrophages - newly discovered mechanism keeps inflammation under control

When macrophages, the first line defender cells of the immune system become activated, they produce an inhibitor, which acts back on them to suppress their activity.

29 Aug 2005

New laboratory method for quickly detecting active anthrax proteins

A new laboratory method for quickly detecting active anthrax proteins within an infected blood sample at extremely low levels has been developed by researchers at the National Institute of Standards and Technology (NIST), the U.S. Army Medical Research Institute of Infectious Diseases and the National Cancer Institute.

29 Aug 2005

Molecular missing link between fasting and acute attacks of porphyria

A team of researchers has discovered a molecular missing link that helps explain why fasting brings on acute attacks of the genetic disease hepatic porphyria, according to a new report in the 26 August issue of the journal Cell.

29 Aug 2005