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Metal-based chemotherapy enhances the effect of cancer immunotherapy

Due to their powerful tumor-killing effect, metal-based chemotherapies are frequently used in cancer treatment. However, it was hitherto assumed that they damaged the immune system, because of their cytotoxic (cell-damaging) effect even against dividing healthy cells.

18 Dec 2018

Sickest children could benefit from split liver transplants

In a review of registry data for more than 5,300 liver transplants performed in children nationwide, Johns Hopkins Medicine researchers identify the type of patient who is most likely to survive a split liver transplant--receiving only part of a donor's liver--with no additional long-term health risks, which could allow for an increase in the availability of organs.

18 Dec 2018

CRISPR may restore effectiveness of chemotherapies used to treat lung cancer

The CRISPR-Cas9 gene editing system may be able to restore the effectiveness of first-line chemotherapies used to treat lung cancer by deleting or "knocking out" a gene in cancer tumors that helps the tumors develop resistance to the drugs.

18 Dec 2018

Scientists create patient-specific model to identify most effective treatment for appendix cancer

Scientists at the Wake Forest Institute for Regenerative Medicine have recently developed a process that may change the way cancer of the appendix is treated in the future.

17 Dec 2018

Russian scientists identify molecular 'switch' that could be target for treatment of allergic asthma

A team of Russian scientists identified the role of the interleukin-6 molecule in the development of allergic asthma. Now it can be a new target for the treatment of this disease. The results are published in Frontiers in Immunology.

17 Dec 2018

New approach to tumor analysis could improve prognosis for bowel cancer patients

Bowel (colorectal) cancer is the third most commonly occurring cancer in men and the second most commonly occurring cancer in women worldwide. The global burden is expected to increase by 60 per cent to more than 2.2 million new cases and 1.1 million deaths by 2030.

17 Dec 2018

DFG establishes nine new Research Units and one new Clinical Research Unit

The Deutsche Forschungsgemeinschaft is establishing nine new Research Units and one new Clinical Research Unit.

17 Dec 2018

CTF along with NTAP and Sage announce first-ever open data portal for neurofibromatosis

The Children's Tumor Foundation, together with the Neurofibromatosis Therapeutic Acceleration Program and Sage Bionetworks, has announced the first-ever open data portal for scientific research results in the field of neurofibromatosis.

17 Dec 2018

New computer model helps predict course of the disease in prostate cancer patients

How does a normal cell turn into a deadly cancer? Seeking an answer to this question, and working alongside other international working groups, researchers from Charité - Universitätsmedizin Berlin examined the tumor genomes of nearly 300 prostate cancer patients.

14 Dec 2018

New drug shows promise in treating sarcomas

A new compound that targets a receptor within sarcoma cancer cells shrank tumors and hampered their ability to spread in mice and pigs, a study from researchers at the University of Illinois reports.

14 Dec 2018

Genetic marker, predictor of early relapse in common childhood cancer discovered

Nova Southeastern University researchers recently discovered that by testing the level of NER (nucleotide excision repair) gene expression, pediatric oncologists can determine the likelihood of early relapse (less than three years) in their acute lymphoblastic leukemia patients.

14 Dec 2018

Researchers discover new mechanism behind spread of malignant pleural mesothelioma

Malignant pleural mesothelioma is divided into three subtypes, one of which is particularly aggressive. Researchers from the Comprehensive Cancer Center of MedUni Vienna and Vienna General Hospital have now managed to discover a mechanism that contributes to this aggressive behavior: the tumor cells of this subtype are able to assume special characteristics that promote migration and therefore spread of the cancer.

13 Dec 2018

Cancer patients have greater risk of developing shingles, study shows

People newly diagnosed with cancer, particularly blood cancers, and those treated with chemotherapy have a greater risk of developing shingles, according to a new study in the Journal of Infectious Diseases.

13 Dec 2018

Exercise may reduce colorectal cancer risk after weight loss

New research suggests that exercise is a key factor in reducing colorectal cancer risk after weight loss. According to the study, physical activity causes beneficial changes in the bone marrow. The study is published ahead of print in the American Journal of Physiology--Endocrinology and Metabolism.

13 Dec 2018

Unraveling the complexity of cancer biology can prompt new avenues for drug development

Unraveling the complexity of cancer biology can lead to the identification of new molecules involved in breast cancer and prompt new avenues for drug development. And proteogenomics, an integrated, multipronged approach, seems to be a way to do it.

13 Dec 2018

New substance could improve efficacy of established breast cancer treatments

Physicians from Karl Landsteiner University of Health Sciences in Krems (Austria) demonstrate potential for clinical application, collaborating with research groups from Germany, the USA, and China.

13 Dec 2018

Nobel Laureates lecture about immune checkpoint therapy for cancer treatment

The Nobel Lectures held by the laureates of the 2018 Nobel Prize in Physiology or Medicine saw Aula Medica at Karolinska Institutet filled to the brink. In addition to 1,000 audience members in the auditorium, people around the world were able to watch the live broadcast when James P. Allison and Tasuku Honjo talked about their research, the results of which have led to the ground-breaking immune checkpoint therapy for cancer treatment.

12 Dec 2018

Faster, cheaper test has potential to enhance prostate cancer evaluation

For men newly diagnosed with prostate cancer or patients previously treated, the risk of metastasis is a crucial determinant of whether to choose conservative management or undergo further treatment.

12 Dec 2018

The EORTC Brain Tumor Group and Protagen AG collaborate to study immuno-competence of long-term glioblastoma survivors

The European Organisation for Research and Treatment of Cancer Brain Tumor Group and Protagen AG today announced a collaboration to utilize Protagen’s Cancer Immunotherapy Array to identify autoantibody biomarkers that investigate the immunological profile and immuno-competence of long-term Glioblastoma survivors.

12 Dec 2018

Whole-body imaging PET/MRI offers information to guide treatment options for prostate cancer

New research on prostate cancer staging shows that PSMA-targeted PET/MRI performs equally as well as currently used predictive tools to determine the risk for advanced disease.

12 Dec 2018

Tumor News and Research

Metal-based chemotherapy enhances the effect of cancer immunotherapy

Sickest children could benefit from split liver transplants

CRISPR may restore effectiveness of chemotherapies used to treat lung cancer

Scientists create patient-specific model to identify most effective treatment for appendix cancer

Russian scientists identify molecular 'switch' that could be target for treatment of allergic asthma

New approach to tumor analysis could improve prognosis for bowel cancer patients

DFG establishes nine new Research Units and one new Clinical Research Unit

CTF along with NTAP and Sage announce first-ever open data portal for neurofibromatosis

New computer model helps predict course of the disease in prostate cancer patients

New drug shows promise in treating sarcomas

Genetic marker, predictor of early relapse in common childhood cancer discovered

Researchers discover new mechanism behind spread of malignant pleural mesothelioma

Cancer patients have greater risk of developing shingles, study shows

Exercise may reduce colorectal cancer risk after weight loss

Unraveling the complexity of cancer biology can prompt new avenues for drug development

New substance could improve efficacy of established breast cancer treatments

Nobel Laureates lecture about immune checkpoint therapy for cancer treatment

Faster, cheaper test has potential to enhance prostate cancer evaluation

The EORTC Brain Tumor Group and Protagen AG collaborate to study immuno-competence of long-term glioblastoma survivors

Whole-body imaging PET/MRI offers information to guide treatment options for prostate cancer

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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