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Researchers use single-cell sequencing to identify cell types that occur in pancreatic tumors

Led by the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, and by HonorHealth Research and Innovation Institute, an international team of researchers have described in detail the individual cells that comprise the pancreatic cancer microenvironment, a critical step in devising new treatment options for patients with this aggressive and difficult-to-treat disease.

1 Oct 2020

Children and young adults have greater potential to transmit SARS-CoV-2 virus

A study of more than a half-million people in India who were exposed to the novel coronavirus SARS-CoV-2, or COVID-19, suggests that the virus' continued spread is driven by only a small percentage of those who become infected.

1 Oct 2020

Scientists discover bacteria linked to post-infectious hydrocephalus in infants

Scientists at the Center for Infection and Immunity at Columbia University Mailman School of Public Health have discovered bacteria linked to post-infectious hydrocephalus (PIH), the most common cause of pediatric hydrocephalus worldwide.

30 Sep 2020

NIH awards $5 million grant to reduce COVID-19-related health disparities

To help reduce COVID-19-related health disparities in vulnerable populations in Texas, a multi-institutional team of researchers led by The University of Texas Health Science Center at Houston will identify disease hotspots and testing deserts in three racially diverse areas, and then develop and evaluate intervention strategies to increase COVID-19 testing.

30 Sep 2020

Persistent-poverty counties face high risk of cancer mortality

Residents of counties that experience persistent poverty face a disproportionately high risk of cancer mortality, according to a study published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.

30 Sep 2020

A TLR2 agonist reduces SARS-CoV-2 in upper respiratory tract of ferret model

In a recent bioRxiv* preprint paper, Professor Miles W. Carroll et al. study an agonist for reducing the SARS-CoV-2's viral load. They show that prophylactic intra-nasal administration of TLR2/6 (toll-like receptor) agonist, INNA-051, reduces viral RNA in the nose and throat, in a ferret model.

30 Sep 2020

Genetic defects in patients' immune system may underlie severe COVID-19

Worldwide, otherwise healthy adolescents and young people without underlying conditions are sometimes severely affected by COVID-19, with the viral infection in the worst cases quickly becoming life-threatening. But why is this happening?

29 Sep 2020

Case fatality rates for COVID-19 and health indicators

Researchers from Turkey and Switzerland collaborated to study the nation-specific case fatality rates for COVID-19 caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The pandemic has affected around 33.5 million people worldwide and killed over 1 million making it one of the largest global health crises in recent memory.

29 Sep 2020

Combined study results present a strong case for lung cancer screening in New Zealand

Newly released study results present a strong case for lung cancer screening in New Zealand - particularly for Māori whose mortality rates are between three and four times higher than other ethnic groups.

29 Sep 2020

How might India's monsoon season impact COVID-19 ?

A new study, by two Goethe University Frankfurt researchers, published on the preprint server medRxiv* in September 2020 explores the relationship between the monsoon season, the chances of exposure to ultraviolet B (UVB) radiation, and the COVID-19 mortality.

29 Sep 2020

Fasting blood glucose levels upon admission tied to COVID-19 prognosis, study finds

In the study, which appeared on the pre-print open-source medRxiv* server, the investigators aimed to determine the prognostic value of blood glucose in predicting outcomes in COVID-19 disease, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

28 Sep 2020

Healthy vitamin D levels could reduce COVID-19 complications

Published in the journal PLOS ONE, the study investigates the link between serum 25-hydroxyvitamin D levels and its effect on adverse clinical outcomes and parameters of immune function and mortality due to COVID-19.

28 Sep 2020

New study reveals the impacts of COVID-19 on unborn children

What are the risks to an unborn child if a woman contracts COVID-19 while pregnant, and how can doctors identify which pregnancies are at greater risk of adverse outcomes if a pregnant mother tests positive?

28 Sep 2020

COVID-19 may deteriorate men's testosterone levels, new data suggests

For the first time, data from a study with patients hospitalized due to COVID-19 suggest that the disease might deteriorate men's testosterone levels.

28 Sep 2020

Newer Type 2 diabetes medications could reduce kidney, heart disease risks

Two newer groups of medications prescribed primarily for Type 2 diabetes treatment (SGLT2 inhibitors and GLP-1 receptor agonists) could significantly reduce risks associated with chronic kidney disease (CKD) and heart disease.

28 Sep 2020

Seniors the optimal target for SARS-CoV-2 vaccination

ith several vaccines already in stage 3 clinical trials, a study by University of Warwick researchers and published on the preprint server medRxiv in September 2020 discusses the use of computer modeling techniques in order to achieve optimal vaccine coverage.

28 Sep 2020

Inhaled corticosteroids may not increase COVID-19 mortality

Inhaled corticosteroids (ICS) are the first line of treatment to counter the inflammatory pathology in several conditions, including asthma and chronic obstructive pulmonary disease (COPD). Now, a new study published in the journal The Lancet Respiratory Medicine in September 2020 reports on the actual role of ICS in reducing COVID-19 mortality.

28 Sep 2020

Anti-N-protein IgG may predict severity of COVID-19

A recent study by researchers at the University of Miami, Miami VA Healthcare System and Express Gene and published on the preprint server medRxiv in September 2020 reports on the prognostic significance of the anti-N Immunoglobulin G (IgG) antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

28 Sep 2020

Risk factors for mortality among hospitalized patients with COVID-19

A new study by scientists at biotechnology company Genentech, Inc., and published on the preprint server medRxiv in September 2020 attempts to identify the factors which may shape the risk for death in COVID-19 disease.

27 Sep 2020

Study reveals the differences in non-COVID-19 hospital admissions during rebound period

While declines in U.S. hospital admissions during the onset of COVID-19 has been well-documented, little is known about how admissions during the rebound varied by age, insurance coverage and socioeconomic groups.

26 Sep 2020