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CMS to cover low-dose CT screening for lung cancer

The Centers for Medicare and Medicaid Services today recognized the importance of lung cancer screening, announcing today that it will cover low-dose computed tomography (CT) screening, or "CAT" scans , for high-risk current and former smokers. The decision validates Mount Sinai's longstanding commitment to providing access to this essential screening tool.

12 Nov 2014

Mayo Clinic study finds that chromosomal rearrangements can help trace lineage of lung cancer

A diagnostic test based on chromosomal rearrangements can trace the lineage of lung cancer to determine whether two separate lung cancers in the same patient are independent tumors or a tumor that has spread to another region of the lung, a Mayo Clinic study has found. For patients with multiple tumors, that distinction could mean the difference between early stage cancer that may be cured by surgery and incurable late-stage disease.

12 Nov 2014

Researchers identify key protein that can reduce severity of disease equivalent to MS in mice

In multiple sclerosis, the immune system goes rogue, improperly attacking the body's own central nervous system. Mobility problems and cognitive impairments may arise as the nerve cells become damaged.

12 Nov 2014

Salivary mucins protect teeth from cariogenic bacterium

Salivary mucins, key components of mucus, actively protect the teeth from the cariogenic bacterium, Streptococcus mutans, according to research published ahead of print in Applied and Environmental Microbiology. The research suggests that bolstering native defenses might be a better way to fight dental caries than relying on exogenous materials, such as sealants and fluoride treatment, says first author Erica Shapiro Frenkel, of Harvard University, Cambridge, MA.

11 Nov 2014

Breakthrough study shows novel molecular imaging drug to detect early prostate cancer

A novel study demonstrates the potential of a novel molecular imaging drug to detect and visualize early prostate cancer in soft tissue, lymph nodes and bone. The research, published in the November issue of the Journal of Nuclear Medicine, compares the biodistribution and tumor uptake kinetics of two Tc-99m labeled ligands, MIP-1404 and MIP-1405, used with SPECT and planar imaging.

11 Nov 2014

New program aims to educate COPD patients on how to manage their disease

The American Thoracic Society today announced a new program, produced with support from Sunovion Pharmaceuticals Inc., to provide materials to educate patients with chronic obstructive pulmonary disease (COPD) about this progressive lung disease and how it can be managed.

11 Nov 2014

Regeneron, Sanofi report positive results from dupilumab Phase 2b study in patients with asthma

Regeneron Pharmaceuticals, Inc. and Sanofi today announced positive results from the interim analysis of a dose-ranging Phase 2b study of dupilumab in adult patients with uncontrolled moderate-to-severe asthma. Dupilumab is an investigational therapy blocking IL-4 and IL-13, two cytokines required for the Th2 immune response.

11 Nov 2014

Lung cancer screening in NLST meets standard for cost effectiveness

Dartmouth researchers say lung cancer screening in the National Lung Screening Trial (NLST) meets a commonly accepted standard for cost effectiveness as reported in the Nov. 6 issue of the New England Journal of Medicine. This relatively new screening test uses annual low-dose CT scans to spot lung tumors early in individuals facing the highest risks of lung cancer due to age and smoking history.

11 Nov 2014

New model explains how immune cells recognize, destroy bacteria

The innate immune system serves as the body's specialized armed forces division, comprised of a host of defense mechanisms used to battle bacterial infections. Among the system's warriors are white blood cells including the specialized macrophages, which maintain constant surveillance for foreign intruders or pathogens, functioning as the body's first line of defense, poised to attack at barrier sites including the skin, lungs and intestines.

11 Nov 2014

Researchers explain interaction between HNRNPA2B1 protein and pancreatic cancer development

Researchers from the University of Barcelona have described an interaction between the protein HNRNPA2B1 and pancreatic cancer development which remained unknown. The study, published in the journal Gastroenterology, has proved in human cancer cell lines that this protein is essential to the correct activity of the oncogenic protein KRAS, related to cancer start and development.

11 Nov 2014

Cigarette smoking increases risk of developing second smoking-associated cancer

Results of a federally-funded pooled analysis of five prospective cohort studies indicate that cigarette smoking prior to the first diagnosis of lung (stage I), bladder, kidney or head and neck cancer increases risk of developing a second smoking-associated cancer. This is the largest study to date exploring risk of second cancers among current smokers.

11 Nov 2014

Inovio Pharmaceuticals reports Q3 2014 financial results, provides corporate update

Inovio Pharmaceuticals, Inc. today reported financial results for the quarter ended September 30, 2014.

10 Nov 2014

New vaccination approach can reduce tumor burden, suppress formation of lung metastases

In a new study published in the scientific journal Oncotarget researchers from Uppsala University show that a therapeutic vaccine directed against tumor vessels can reduce tumor burden and suppress formation of spontaneous lung metastases in a mouse model for metastatic breast cancer.

9 Nov 2014

Exposure to indoor air pollution affects children's lungs

Children with asthma and hay fever often struggle with their breathing. Add secondhand smoke, kerosene and biomass fuel to the mix and allergy and asthma symptoms increase.

7 Nov 2014

New algorithm could help determine how to treat patients having difficulty breathing

Paramedics respond to a 911 call to find an elderly patient who's having difficulty breathing. Anxious and disoriented, the patient has trouble remembering all the medications he's taking, and with his shortness of breath, speaking is difficult. Is he suffering from acute emphysema or heart failure? The symptoms look the same, but initiating the wrong treatment regimen will increase the patient's risk of severe complications.

7 Nov 2014

Integrative medicine therapies can decrease pain, anxiety for hospitalized cancer patients

Pain is a common symptom of cancer and side effect of cancer treatment, and treating cancer-related pain is often a challenge for health care providers.

7 Nov 2014

UCSD engineers propose new single-ventricle heart surgery for children

Engineers at the University of California, San Diego, are proposing a new surgical intervention for children born with a single ventricle in their heart--instead of the usual two. The new approach would potentially reduce the number of surgeries the patients have to undergo in the first six months of life from two to just one. If successful, it would also create a more stable circuit for blood to flow from the heart to the lungs and the rest of the body within the first days and months of life.

6 Nov 2014

Lungs News and Research

CMS to cover low-dose CT screening for lung cancer

Mayo Clinic study finds that chromosomal rearrangements can help trace lineage of lung cancer

Researchers identify key protein that can reduce severity of disease equivalent to MS in mice

Salivary mucins protect teeth from cariogenic bacterium

Breakthrough study shows novel molecular imaging drug to detect early prostate cancer

New program aims to educate COPD patients on how to manage their disease

Regeneron, Sanofi report positive results from dupilumab Phase 2b study in patients with asthma

Lung cancer screening in NLST meets standard for cost effectiveness

New model explains how immune cells recognize, destroy bacteria

Researchers explain interaction between HNRNPA2B1 protein and pancreatic cancer development

Cigarette smoking increases risk of developing second smoking-associated cancer

Inovio Pharmaceuticals reports Q3 2014 financial results, provides corporate update

New vaccination approach can reduce tumor burden, suppress formation of lung metastases

Exposure to indoor air pollution affects children's lungs

New algorithm could help determine how to treat patients having difficulty breathing

Integrative medicine therapies can decrease pain, anxiety for hospitalized cancer patients

UCSD engineers propose new single-ventricle heart surgery for children

Researchers develop diagnostic tool to examine traveling cancer cells, improve health outcomes

Discovery Laboratories reports net loss of $11.3 million for third quarter 2014

EKF Molecular Diagnostics to present at AMP annual meeting

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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