Small Molecules News and Research

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New immuno-assay can detect small molecules with 50-fold greater sensitivity

As medical science has come to understand that the human body is controlled on the molecular level by various proteins, hormones, drugs, and other substances, technologies have developed to detect levels of these molecules in order to monitor health and diagnose disease.

6 Dec 2018

Sleeping sickness study could aid efforts to beat the disease

Key insights into how the parasites behind sleeping sickness boost their ability to spread could aid efforts to beat the disease.

29 Nov 2018

New dye is a step towards personalized neuromedical prophylaxis of the future

Signs of neurodegenerative diseases, visible years before the emergence of clinical manifestations, can be detected during the examination of medical samples by means of fluorescence microscopy.

29 Nov 2018

Scientists develop new technique for identifying small molecules

A UCLA-led team of scientists has developed a new technique that will enable researchers to easily and quickly determine the structures of organic molecules using very small samples.

28 Nov 2018

Using Pre-Clinical Imaging to Detect Cancer

In this interview, Émilie Beaulieu Ouellet, Application Scientist for life science imaging at Photon Etc talks to New-Medical about their range of preclinical infrared imagers and how they can allow cancer detection.

From Photon etc. 27 Nov 2018

Researchers identify powerful inhibitor of epigenetic factors that promote acute myeloid leukemia

Some severe forms of leukemia develop because proteins on the epigenetic level lose their regulative function. Now, in a broad international collaboration, UK researchers have identified molecules that can effectively inhibit the dysregulated proteins.

27 Nov 2018

Scientists use cryo-EM to capture freeze-frames of molecule’s 'lock-and-load' on DNA

Pushing the limits of cryo-electron microscopy, University of California, Berkeley, scientists have captured freeze-frames of the changing shape of a huge molecule, one of the body's key molecular machines, as it locks onto DNA and loads the machinery for reading the genetic code.

20 Nov 2018

Nicoya designate the Institute for Stem Cell Biology and Regenerative Medicine as the OpenSPR Centre of Excellence

Currently in India, there are over 200,000 researchers working on numerous applications to better understand diseases and advance drug discovery. To support their discoveries, we are thrilled to announce the opening of the OpenSPR Centre of Excellence in Bangalore, India!

From Nicoya Lifesciences 15 Nov 2018

Researchers develop powerful method to solve structures of small molecules

Small molecules -- from naturally occurring metabolites and hormones to synthetic medicines and pesticides -- can have big effects on living things. But for scientists to understand how the molecules work and how to design beneficial ones, they need to know the precise arrangement of atoms and chemical bonds.

9 Nov 2018

Small molecules designed to inhibit activity of enzymes in infectious diseases

A multidisciplinary study by the Computer Biochemistry Research Group of the Universitat Jaume I from Castellón, Spain, in collaboration with groups from universities from Canada and the United Kingdom, have designed small molecules that are able to bond with and inhibit the activity of enzymes in infectious diseases.

8 Nov 2018

New research explains how large virus shells are formed

A virus, the simplest physical object in biology, consists of a protein shell called the capsid, which protects its nucleic acid genome -- RNA or DNA. The capsid can be cylindrical or conical in shape, but more commonly it assumes an icosahedral structure, like a soccer ball.

5 Nov 2018

Molecular virologist uses basic science to fight influenza

Molecular virologist Chad Petit, Ph.D., uses basic science to fight influenza -- through experiments at the atomic level.

3 Nov 2018

Researchers develop new strategy in the search for psychoactive drugs

Researchers at the University of Zurich and Harvard University have developed a new strategy in the search for psychoactive drugs.

1 Nov 2018

IU Philanthropic Venture Fund commits to invest $500,000 to NERx Biosciences company

The Indiana University Philanthropic Venture Fund, which provides capital to faculty, students, alumni and staff at all IU campuses to help them further develop their research and innovations into startup companies, has committed to invest $500,000 in Indianapolis-based NERx Biosciences Inc. as part of a $2.2 million bridge round.

1 Nov 2018

Organ-on-a-chip model helps explore underlying pathways shared by stroke and dementia

Stroke is the second main cause of death globally, and a major cause of disability. Around 15 million people worldwide suffer a stroke each year, and rates are climbing, with the number of strokes in Europe set to increase by 1.5 million per year by 2025 – due in large part to the aging population.

29 Oct 2018

Researchers identify new potential target to inhibit progression of liver disease

Naglaa Shoukry, Ph. D., and her team have made a significant breakthrough in their research aiming to limit the progression of liver disease.

26 Oct 2018

Scientists develop new class of compounds for treatment of progressive neurodegenerative disorder

St. Jude Children's Research Hospital investigators have developed a new class of compounds that extended the lives and eased symptoms of mice with a progressive neurodegenerative human disorder.

23 Oct 2018

CLARIOstar used for fluorescence measurements on CSIRO's purpose-built research vessel

Professor Peter Karuso, from the Department of Molecular Sciences at Macquarie University, recently set sail on the CSIRO's purpose-built research vessel, the RV Investigator, on a 31 day voyage that covered over 2,600 nautical miles off the Western Australian coast.

From BMG LABTECH GmbH 19 Oct 2018

Mice study shows antibiotics are not always necessary to cure sepsis

Biochemists, microbiologists, drug discovery experts and infectious disease doctors have teamed up in a new study that shows antibiotics are not always necessary to cure sepsis in mice.

17 Oct 2018

Yale researchers develop way to attack RNA with small-molecule drugs

Yale researchers have developed a way to target RNA with small-molecule drugs, creating a new method for tapping into a vast number of biological mechanisms critical to metabolism and gene expression.

15 Oct 2018