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FDA permits marketing of ClonoSEQ assay to detect minimal residual disease in blood cancer patients

Today the U.S. Food and Drug Administration permitted marketing of ClonoSEQ assay, a next generation sequencing-based test for minimal residual disease in patients with acute lymphoblastic leukemiaor multiple myeloma. MRD is a measure of the amount of cancer cells remaining in a person's bone marrow.

30 Sep 2018

$Bacterial therapy shows early clinical efficacy in patients with treatment-refractory solid tumors$

Bacterial therapy shows early clinical efficacy in patients with treatment-refractory solid tumors

A phase I clinical trial investigating the use of bacterial Clostridium novyi-NT spores as an injectable monotherapy had manageable toxicities and showed early clinical efficacy in patients with treatment-refractory solid tumor malignancies, according to data presented at the Fourth CRI-CIMT-EATI-AACR International Cancer Immunotherapy Conference: Translating Science into Survival, held Sept. 30-Oct. 3.

30 Sep 2018

Cancer undercuts ability of normal cells to consume glucose, finds study

Cancer needs energy to drive its out-of-control growth. It gets energy in the form of glucose, in fact consuming so much glucose that one method for imaging cancer simply looks for areas of extreme glucose consumption - where there is consumption, there is cancer.

29 Sep 2018

FDA approves first intravenous treatment for metastatic cutaneous squamous cell carcinoma

The U.S. Food and Drug Administration today approved Libtayo (cemiplimab-rwlc) injection for intravenous use for the treatment of patients with metastatic cutaneous squamous cell carcinoma or locally advanced CSCC who are not candidates for curative surgery or curative radiation.

28 Sep 2018

Researchers create photoswitchable fluorescent proteins with optical properties

Researchers developed fluorescent proteins that can be controlled by orange and green light. These proteins will help to study processes in living cells. The work was supported by Russian Science Foundation grant, and the results were published in Nature Methods.

28 Sep 2018

Researchers decipher antitumor mechanism of Amazonian plant in human cancer cells

A piece of research conducted by the Free Radicals and Oxidative Stress Group at the UPV/EHU's Faculty of Medicine and Nursing has deciphered the antitumor mechanism exerted by the plant Vismia baccifera, originally from the Amazonian region of Colombia, in human liver cancer cells.

28 Sep 2018

Synthetic DNA vaccine targets proteins overexpressed in several types of cancer

Scientists at The Wistar Institute have implemented a novel structurally designed synthetic DNA vaccine to simultaneously target multiple members of a family of proteins that are specifically overexpressed in several types of cancer.

28 Sep 2018

New combination therapy shows potential in treating incurable HPV-related cancers

A tumor-specific vaccine combined with an immune checkpoint inhibitor shrank tumors in one third of patients with incurable cancer related to the human papilloma virus (HPV) in a phase II clinical trial led by investigators at The University of Texas MD Anderson Cancer Center and reported in JAMA Oncology.

28 Sep 2018

UA professor receives NSF grant to study role of stromal cells in breast cancer

Hossein Tavana, Ph.D., an associate professor of biomedical engineering at The University of Akron (UA), has received a single-PI grant in the amount of $328,426 from the National Science Foundation - his third federal grant this year - to study the role of stromal cells in cancer.

28 Sep 2018

CNL, TRIUMF team up to enable revolutionary cancer treatment

TRIUMF, Canada's particle accelerator center, and Canadian Nuclear Laboratories, Canada's premier nuclear science and technology organization, are pleased to announce that they have agreed to pursue a strategic partnership around the commercial production of Actinium-225, a rare medical isotope that has the potential to serve as the basis of new ground-breaking cancer treatments.

28 Sep 2018

Verastem Oncology selects US Bioservices to dispense COPIKTRA capsules

US Bioservices, a specialty pharmacy that is a part of AmerisourceBergen, today announced that it has been selected by Verastem OncologyTM to dispense COPIKTRA (duvelisib) capsules.

28 Sep 2018

FLX Bio treats first patient in its Phase 1/2 clinical trial of FLX475 for treating various advanced cancers

FLX Bio, Inc., a clinical-stage, biopharmaceutical company focused on the development of oral small-molecule drugs that target drivers of cancer and other immune-related disorders, today announced that the first patient has been treated in its Phase 1/2 clinical trial of FLX475 in patients with various advanced cancers. FLX475 is an oral, small molecule CCR4 antagonist that selectively inhibits migration of regulatory T cells into the tumor microenvironment.

27 Sep 2018

Crown Bioscience announces successful validation of well-characterized prostate cancer PDX models

Crown Bioscience, a global drug discovery and development services company providing translational platforms to advance oncology, inflammation, cardiovascular and metabolic disease research, has announced the addition of unique, well characterized, fully annotated patient-derived xenograft models of prostate cancer.

27 Sep 2018

Cornwall and Chongqing Haifu partners to introduce HIFU tumor therapy system

Cornwall Medical Group enters a strategic partnership with the world's leading medical equipment and integrated solutions provider, Chongqing Haifu Medical Technology Co., Ltd., to introduce innovative high-intensity focused ultrasound tumor therapy system to Hong Kong, positioned to be the first minimally-invasive & non-invasive center in town.

27 Sep 2018

Olfactory cells could act as 'Trojan horse,' delivering anticancer therapy to dangerous brain tumors

A special type of cell essential to the ability of olfactory neurons to regenerate may be genetically engineered to deliver anticancer therapy to the dangerous brain tumors called glioblastomas.

27 Sep 2018

Researchers take first steps in developing 'paintable' chemotherapy for melanoma

Skin acts as the first line of defense against pathogens and other harmful material from outside the body. Yet this barrier also excludes some beneficial drugs that could treat skin diseases.

26 Sep 2018

Drosophila study shows chromosomal instability promotes invasive behavior in human tumors

Metastatic tumors are characterized by a high degree of chromosomal instability--that is to say a constant change in the number and structure of chromosomes they hold. In spite of this observation, it is unknown whether chromosomal instability contributes to the metastatic process.

26 Sep 2018

Tumor News and Research

FDA permits marketing of ClonoSEQ assay to detect minimal residual disease in blood cancer patients

Bacterial therapy shows early clinical efficacy in patients with treatment-refractory solid tumors

Cancer undercuts ability of normal cells to consume glucose, finds study

FDA approves first intravenous treatment for metastatic cutaneous squamous cell carcinoma

Researchers create photoswitchable fluorescent proteins with optical properties

Researchers decipher antitumor mechanism of Amazonian plant in human cancer cells

Synthetic DNA vaccine targets proteins overexpressed in several types of cancer

New combination therapy shows potential in treating incurable HPV-related cancers

UA professor receives NSF grant to study role of stromal cells in breast cancer

CNL, TRIUMF team up to enable revolutionary cancer treatment

Verastem Oncology selects US Bioservices to dispense COPIKTRA capsules

FLX Bio treats first patient in its Phase 1/2 clinical trial of FLX475 for treating various advanced cancers

Crown Bioscience announces successful validation of well-characterized prostate cancer PDX models

Cornwall and Chongqing Haifu partners to introduce HIFU tumor therapy system

Olfactory cells could act as 'Trojan horse,' delivering anticancer therapy to dangerous brain tumors

Researchers take first steps in developing 'paintable' chemotherapy for melanoma

Drosophila study shows chromosomal instability promotes invasive behavior in human tumors

Urine liquid biopsies could help monitor response to immunotherapy in bladder cancer patients

Exploring parallels between biological and computing world

New findings show importance of physical forces in tumor metastasis

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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