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Scientists gain better understanding of tumor initiation and metastasis in colon cancer patients

Researchers from the University of Luxembourg have discovered a molecular mechanism that is responsible for the spread of cancer cells in the body and the development of metastases in patients with colon cancer. Their findings could help to develop treatments that inhibit tumor growth.

11 Sep 2018

Gene involved in circadian rhythms can be potential target for glioblastoma treatment

Scientists with the Virginia Tech Carilion Research Institute say a gene involved in the body's circadian rhythms is a potential target for therapies to help patients with a deadly form of brain cancer known as glioblastoma.

11 Sep 2018

Synergism between HOXB13 and CIP2A genes predisposes men to get prostate cancer

A research team at the University of Turku in Finland discovered a link between the interplay of certain simultaneously occurring genetic changes in the HOXB13 and CIP2A genes, aggressiveness of prostate cancer, high risk of developing the disease, and poorer survival rates of patients.

11 Sep 2018

Barrow Institute initiates $50 million effort to seek cure for glioblastoma

Barrow Neurological Institute has initiated a $50 million effort, supported by the single largest research grant in the history of brain tumor research, to seek a cure for the deadliest form of brain cancer.

11 Sep 2018

CRI to bestow top honors on three scientists for contributions to cancer immunology and immunotherapy

The Cancer Research Institute, a nonprofit organization dedicated to the discovery and development of immunotherapies for all forms of cancer, will bestow its highest honors on three scientists who have made fundamental contributions to the fields of immunology and cancer immunotherapy.

11 Sep 2018

BAP1 protein serves as tumor suppressor gene in kidney, eye, bile duct and mesothelioma cancers

Researchers at The University of Texas MD Anderson Cancer Center have shown how BRCA-associated protein 1 (BAP1) serves as a tumor suppressor gene in kidney, eye, bile duct, mesothelioma and other cancers by regulating a form of cell death called ferroptosis, opening up a potential new area of therapy research.

10 Sep 2018

Mouse study suggests new therapeutic approach to treat heart failure

A heart attack triggers an acute inflammatory response, followed by resolution of inflammation and wound healing. A severe heart attack, however, can cause chronic and sustained inflammation that leads to heart failure and death.

10 Sep 2018

Researchers uncover secret of immortality mechanism in aggressive glioblastoma

UC San Francisco researchers have discovered how a mutation in a gene regulator called the TERT promoter -- the third most common mutation among all human cancers and the most common mutation in the deadly brain cancer glioblastoma -- confers "immortality" on tumor cells, enabling the unchecked cell division that powers their aggressive growth.

10 Sep 2018

Individualized therapies targeting specific features show promise in transforming cancer treatment

Individualized therapies that target the specific genetic features of tumors have the potential to transform cancer diagnosis, treatment and care.

10 Sep 2018

Acute changes in extracellular matrix can trigger rapid change in cell’s metabolism

UCLA researchers have found that the extracellular matrix, the dense network of proteins and carbohydrates that surround a cell, can influence how cells move within the body by regulating their sugar consumption.

10 Sep 2018

Averaging results from two independent participants improves screening accuracy

Averaging the results from two independent participants improved screening accuracy, whether participants were looking at baggage scans or mammograms, according to findings published in Psychological Science, a journal of the Association for Psychological Science.

10 Sep 2018

Enhanced ultrasound can eliminate need for unnecessary biopsies and surgeries, shows study

A simple enhanced ultrasound scan of the kidney is more accurate than computed tomography and magnetic resonance imaging in predicting whether suspicious masses are cancerous -- and can eliminate the need for unnecessary biopsies and surgeries, according to a 10-year study presented today at an international medical conference in Chicago.

7 Sep 2018

NCCN updates Clinical Practice Guidelines to include new recommendations for CABOMETYX tablets

Exelixis, Inc. today announced that the National Comprehensive Cancer Network updated its Clinical Practice Guidelines to include new recommendations for CABOMETYX tablets.

7 Sep 2018

Hsp90 protein appears to stimulate exosome release

Researchers from the Verstreken lab have identified a completely novel function for Hsp90, one of the most common and most studied proteins in our body.

7 Sep 2018

Immune checkpoint inhibition may be effective in treating HIV-associated Kaposi's sarcoma

Among a small cohort of patients with HIV-associated Kaposi's sarcoma treated with immune checkpoint inhibitors, more than 65 percent had partial or complete remission.

7 Sep 2018

Researchers test experimental cancer vaccine on mice with aggressive melanoma

An experimental cancer vaccine that boosts the immune system's ability to fight cancers could work in tandem with other cancer therapies to fight aggressive tumors, scientists reported recently in the Proceedings of the National Academy of Sciences.

7 Sep 2018

Researchers reveal how rapidly spreading ovarian cancer cells take the next steps

In nearly 80 percent of women with ovarian cancer, the disease has already spread to the omentum before it was diagnosed. Within the omentum -; a large, energy-dense fat pad that covers the intestines -; the cancer grows even faster.

7 Sep 2018

Endocrine Society announces winners of prestigious 2019 Laureate Awards

The Endocrine Society today announced it has chosen 13 leading endocrinologists as winners of its prestigious 2019 Laureate Awards, the top honors in the field.

6 Sep 2018

New diagnostic tool for difficult-to-detect cancers

A new diagnostic tool is expected to result in better treatment of cancer that is difficult to diagnose. The tool was developed by cancer researchers at Sahlgrenska Academy and doctors at the Sahlgrenska University Hospital, Sweden. Their study, which has been published in JCO Precision Oncology, started with a single cancer patient.

6 Sep 2018

Natural plant compound exploits newly identified Achilles' heel in uveal melanoma

A natural plant compound exploits a newly identified Achilles' heel in a cancer of the eye, uveal melanoma. In human cancer cells growing in the lab, the compound shuts down the overactive signaling that drives uveal melanoma cell growth, according to researchers at Washington University School of Medicine in St. Louis.

6 Sep 2018

Tumor News and Research

Scientists gain better understanding of tumor initiation and metastasis in colon cancer patients

Gene involved in circadian rhythms can be potential target for glioblastoma treatment

Synergism between HOXB13 and CIP2A genes predisposes men to get prostate cancer

Barrow Institute initiates $50 million effort to seek cure for glioblastoma

CRI to bestow top honors on three scientists for contributions to cancer immunology and immunotherapy

BAP1 protein serves as tumor suppressor gene in kidney, eye, bile duct and mesothelioma cancers

Mouse study suggests new therapeutic approach to treat heart failure

Researchers uncover secret of immortality mechanism in aggressive glioblastoma

Individualized therapies targeting specific features show promise in transforming cancer treatment

Acute changes in extracellular matrix can trigger rapid change in cell’s metabolism

Averaging results from two independent participants improves screening accuracy

Enhanced ultrasound can eliminate need for unnecessary biopsies and surgeries, shows study

NCCN updates Clinical Practice Guidelines to include new recommendations for CABOMETYX tablets

Hsp90 protein appears to stimulate exosome release

Immune checkpoint inhibition may be effective in treating HIV-associated Kaposi's sarcoma

Researchers test experimental cancer vaccine on mice with aggressive melanoma

Researchers reveal how rapidly spreading ovarian cancer cells take the next steps

Endocrine Society announces winners of prestigious 2019 Laureate Awards

New diagnostic tool for difficult-to-detect cancers

Natural plant compound exploits newly identified Achilles' heel in uveal melanoma

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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