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USC scientists develop new way to identify molecular markers of breast cancer tumors

A research team led by USC scientists has developed a new way to identify molecular markers of breast cancer tumors, a potentially life-saving breakthrough that could lead to better treatment for millions of women.

6 Sep 2018

Verastem doses first patient in Phase I/II clinical trial of duvelisib in combination with venetoclax

Verastem, Inc., operating as Verastem Oncology, a biopharmaceutical company focused on developing and commercializing medicines to improve the survival and quality of life of cancer patients, today announced dosing of the first patient in a multicenter Phase I/II clinical trial at the Dana-Farber/Harvard Cancer Center of duvelisib in combination with venetoclax in patients with relapsed or refractory chronic lymphocytic leukemia or small lymphocytic lymphoma.

6 Sep 2018

BeiGene collaborates with SpringWorks to evaluate new combinational therapy for solid tumors

BeiGene, Ltd., a commercial-stage biopharmaceutical company focused on developing and commercializing innovative molecularly-targeted and immuno-oncology drugs for the treatment of cancer, and SpringWorks Therapeutics, a clinical-stage rare disease and oncology company focused on sourcing and developing innovative treatments for underserved patient populations, announced today that the companies have entered into a global clinical collaboration agreement to evaluate the safety, tolerability and preliminary efficacy of combining BeiGene's investigational RAF dimer inhibitor, lifirafenib and SpringWorks Therapeutics' investigational MEK inhibitor, PD-0325901, in patients with advanced solid tumors.

6 Sep 2018

Researchers discover natural plant compound that shuts down uveal melanoma cell growth

A natural plant compound exploits a newly identified Achilles' heel in a cancer of the eye, uveal melanoma.

6 Sep 2018

New nuclear medicine imaging method could help diagnose widespread tumors

A new nuclear medicine imaging method could help diagnose widespread tumors, such as breast, colon, pancreas, lung and head and neck cancer better than current methods, with less inconvenience to patients and with equal or improved accuracy.

6 Sep 2018

‘Chromosomal catastrophes’ found to occur along evolutionary timeline of bowel cancer

'Chromosomal catastrophes' have been found to occur along the evolutionary timeline of colorectal cancer development, according to new research led by Queen Mary University of London.

5 Sep 2018

Research shows new way to target drug delivery for brain tumors

A person's brainstem controls some of the body's most important functions, including heart beat, respiration, blood pressure and swallowing. Tumor growth in this part of the brain is therefore twice as devastating.

5 Sep 2018

Tipping the scales to initiate tumorigenesis in the colon

The regulatory protein c-MYC plays an important role in promoting the development of many types of tumors. c-MYC is a transcription factor that controls the activity of large numbers of genes involved in cell division, and its overexpression leads to excessive cell proliferation.

5 Sep 2018

Link discovered between tumor genome changes and mortality risk across cancer types

Researchers have discovered a link between certain changes in the genome of a tumor and increased chances of death across multiple types of cancer.

5 Sep 2018

Researchers discover how a protein complex safeguards against certain brain tumors

Researchers have discovered how a molecule can help prevent certain types of brain tumors by recognizing and 'disarming' harmful proteins that cause them.

5 Sep 2018

Study finds new clues to understand relapse in breast cancer

A large genomic analysis has linked certain DNA mutations to a high risk of relapse in estrogen receptor positive breast cancer, while other mutations were associated with better outcomes, according to researchers from Washington University School of Medicine in St. Louis, the Baylor College of Medicine and the University of British Columbia.

4 Sep 2018

Anti-inflammatory use during surgery may lead to improved outcomes for cancer patients

The world's first clinical trial (SURGUVANT) evaluating anti-inflammatory use at the time of surgery in colon cancer patients to improve their cancer outcome has been published in scientific journal, BMC Cancer.

4 Sep 2018

Improving neurosurgery for malignant brain tumors

Important research by Barrow Neurological Institute neurosurgeons and University of Washington (UW) scientists on novel imaging technology for malignant brain tumors was published in the August issue of the Nature journal, Scientific Reports.

4 Sep 2018

Image Cytometry Technology and Tissue Analysis

Image cytometry or tissue cytometry, not only measures the size, diameter and shape of a cell, but quantifies the molecular marker expression.

From TissueGnostics 4 Sep 2018

Creating rituals to honor the dead at long-term-care facilities

One by one, their names were recited as family members clutched one another's hands and silently wept.

4 Sep 2018

Five microRNAs predict course, recurrence of HPV-negative head and neck cancer

A new method predicts the course of HPV-negative head and neck cancer after radiation chemotherapy.

4 Sep 2018

Social environment plays substantial role in progression of noncontagious diseases

What if social behavior affected the progression of even noncontagious diseases? This is precisely what has been demonstrated by French CNRS teams, with support from the French National Research Institute for Sustainable Development, Paris-Sud University, the University of Montpellier, the French Alternative Energies and Atomic Energy Commission, and colleagues from Spain and Australia.

3 Sep 2018

Scientists identify 'Achilles heel' of anaplastic large-cell lymphomas

Anaplastic large-cell lymphomas are rare cancers of the white blood cells. New research from the international ERIA consortium, led by scientists in Vienna, has now shown that the same signaling pathway is essential to the growth of cancer cells in various forms of ALCL: TYK2 (tyrosine kinase 2, an important component of the immune system) prevents apoptotic cell death by increasing the production of Mcl1, a special type of protein belonging to the BCL2 family.

3 Sep 2018

Genetic mutations may drive tumor formation by blurring growth signals

Genetic mutations in a form of non-small cell lung cancer (NSCLC) may drive tumor formation by blurring cells' perception of key growth signals, according to a new laboratory study published August 31, 2018 in Science.

3 Sep 2018

Research group aims to offer more personalized treatments for pediatric cancers

A new Emmy Noether Independent Junior Research Group at Charité - Universitätsmedizin Berlin is studying the development of pediatric cancers. The research group is being funded by the German Research Foundation (DFG) and will receive €1.7 million over five years.

31 Aug 2018

Tumor News and Research

USC scientists develop new way to identify molecular markers of breast cancer tumors

Verastem doses first patient in Phase I/II clinical trial of duvelisib in combination with venetoclax

BeiGene collaborates with SpringWorks to evaluate new combinational therapy for solid tumors

Researchers discover natural plant compound that shuts down uveal melanoma cell growth

New nuclear medicine imaging method could help diagnose widespread tumors

‘Chromosomal catastrophes’ found to occur along evolutionary timeline of bowel cancer

Research shows new way to target drug delivery for brain tumors

Tipping the scales to initiate tumorigenesis in the colon

Link discovered between tumor genome changes and mortality risk across cancer types

Researchers discover how a protein complex safeguards against certain brain tumors

Study finds new clues to understand relapse in breast cancer

Anti-inflammatory use during surgery may lead to improved outcomes for cancer patients

Improving neurosurgery for malignant brain tumors

Image Cytometry Technology and Tissue Analysis

Creating rituals to honor the dead at long-term-care facilities

Five microRNAs predict course, recurrence of HPV-negative head and neck cancer

Social environment plays substantial role in progression of noncontagious diseases

Scientists identify 'Achilles heel' of anaplastic large-cell lymphomas

Genetic mutations may drive tumor formation by blurring growth signals

Research group aims to offer more personalized treatments for pediatric cancers

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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