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CRISPR/Cas9 system is highly effective in treating metastatic cancers

Researchers at Tel Aviv University (TAU) have demonstrated that the CRISPR/Cas9 system is very effective in treating metastatic cancers, a significant step on the way to finding a cure for cancer.

19 Nov 2020

Domestic cats can be asymptomatic carriers of SARS-CoV-2, show studies

Two recently published studies from Kansas State University researchers and collaborators have led to two important findings related to the COVID-19 pandemic: Domestic cats can be asymptomatic carriers of SARS-CoV-2, but pigs are unlikely to be significant carriers of the virus. SARS-CoV-2 is the coronavirus responsible for COVID-19.

19 Nov 2020

Alzheimer's study shows tau protein changes according to dementia stage

Research into Alzheimer's disease has long focused on understanding the role of two key proteins, beta amyloid and the tau protein. Found in tangles in patients' brain tissue, a pathological form of the tau protein contributes to propagating the disease in the brain.

19 Nov 2020

TB researchers uncover crucial clue that explains antibiotic resistance in bacteria

For a slow-growing microbe that multiplies infrequently, Mycobacterium tuberculosis, the pathogen that causes tuberculosis (TB) has long puzzled researchers as to how it develops resistance to antibiotics so quickly, in a matter of weeks to months.

18 Nov 2020

Study provides new insight into the formation of neural crest cells

Last year, researchers at the University of California, Riverside, identified the early origins of neural crest cells -- embryonic cells in vertebrates that travel throughout the body and generate many cell types -- in chick embryos.

18 Nov 2020

UTHSC and Regeneron partner to advance precision medicine

The University of Tennessee Health Science Center has entered into an agreement with the Regeneron Genetics Center, a subsidiary of Regeneron Pharmaceuticals, Inc., for the company to sequence DNA that has been voluntarily collected and stored as part of a biorepository initiative UTHSC is building in collaboration with its partner teaching hospitals.

18 Nov 2020

Researchers use proteogenomics to better understand the biological complexity of breast cancer

Researchers at Baylor College of Medicine, the Broad Institute of MIT and Harvard and other institutions have applied powerful proteogenomics approaches to better understand the biological complexity of breast cancer.

18 Nov 2020

UC researcher receives $443,000 NIH grant to study antiviral drugs

University of Cincinnati pharmaceutical sciences researcher Bingfang Yan, DVM, has received a $443,000 grant from the National Institutes of Health to study how common medicines against viral infections are genetically impacted for therapeutic effectiveness and safety through metabolic conversions in the body.

18 Nov 2020

Computational method could predict immunotherapy response in patients with advanced melanoma

A computational method that combines clinicodemographic variables with deep learning of pre-treatment histology images could predict response to immune checkpoint blockade among patients with advanced melanoma.

18 Nov 2020

Vitamin D3 supplementation shows no therapeutic benefits in severe COVID-19 patients, study finds

A team of researchers at the University of São Paulo in Brazil aimed to determine if vitamin D3 supplementation reduces the length of stay in hospitalized patients with severe COVID-19.

18 Nov 2020

How weather affects SARS-CoV-2 transmission: A US-based case study

How changes in the weather affect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been the topic of several studies. The preoccupation of researchers with this aspect of the coronavirus disease 2019 (COVID-19) pandemic follows from observations that the flu virus and other coronaviruses follow seasonal patterns. Understanding how SARS-CoV-2’s transmissibility is affected by seasonal changes can thus help us to develop more informed preventative measures against its spread.

18 Nov 2020

Government-funded scientists laid the groundwork for billion-dollar vaccines

When he started researching a troublesome childhood infection nearly four decades ago, virologist Dr. Barney Graham, then at Vanderbilt University, had no inkling his federally funded work might be key to deliverance from a global pandemic.

18 Nov 2020

Cannabidiol oils are equally or less effective at inhibiting certain cancer cell lines

Cannabidiol (CBD) oils are equally or less effective at inhibiting the growth of certain cancer cells compared to pure CBD, according to Penn State College of Medicine researchers.

18 Nov 2020

Children in Melbourne family developed COVID-19 immune response after exposure to virus

Children in a Melbourne family developed a COVID-19 immune response after chronic exposure to the SARS-CoV-2 virus from their parents, a new case report has found.

18 Nov 2020

Certain regions in the retina are more affected by Alzheimer's disease, shows study

A study led by the Cedars-Sinai Department of Neurosurgery has identified certain regions in the retina - the lining found in the back of the eye - that are more affected by Alzheimer's disease than other areas.

18 Nov 2020

Study highlights the disproportionate burden of COVID-19 among Black, Hispanic patients

Research presented today by UT Southwestern cardiologists at the annual American Heart Association (AHA) Scientific Sessions 2020 showed that Black and Hispanic people were more likely to be hospitalized with COVID-19 than white patients, and that nonwhite men with cardiovascular disease or risk factors were more likely to die.

18 Nov 2020

SARS-CoV-2 was circulating in Italy before China recognized its existence

This study, published in the Tumori Journal, sheds light on the possibility that the virus had been spreading in Italy well before the outbreak was officially reported in Wuhan, China.

17 Nov 2020

LOX plays a number of key roles in promoting skin and organ fibrosis in scleroderma

A team of researchers at the Medical University of South Carolina (MUSC) has found that the molecule lysyl oxidase (LOX) plays a number of important roles in promoting skin and organ fibrosis in scleroderma, a connective tissue disorder.

17 Nov 2020

New multiplex assay can be used for epidemiological surveillance, management of COVID-19

Scientists from Northwell Health Laboratories have developed a new diagnostic multiplex assay that can be used for epidemiological surveillance and clinical management of COVID-19.

17 Nov 2020

New AHA COVID-19 CVD Registry details the disparities in care

A new American Heart Association collaborative model for COVID-19 research, using data from the new AHA COVID-19 Cardiovascular Disease Registry, found Hispanic and Black adults with COVID-19 were far more likely to be hospitalized than their white counterparts, as were people with obesity and COVID-19, according to three late-breaking research studies presented today at the American Heart Association's Scientific Sessions 2020.

17 Nov 2020

Laboratory News and Research

CRISPR/Cas9 system is highly effective in treating metastatic cancers

Domestic cats can be asymptomatic carriers of SARS-CoV-2, show studies

Alzheimer's study shows tau protein changes according to dementia stage

TB researchers uncover crucial clue that explains antibiotic resistance in bacteria

Study provides new insight into the formation of neural crest cells

UTHSC and Regeneron partner to advance precision medicine

Researchers use proteogenomics to better understand the biological complexity of breast cancer

UC researcher receives $443,000 NIH grant to study antiviral drugs

Computational method could predict immunotherapy response in patients with advanced melanoma

Vitamin D3 supplementation shows no therapeutic benefits in severe COVID-19 patients, study finds

How weather affects SARS-CoV-2 transmission: A US-based case study

Government-funded scientists laid the groundwork for billion-dollar vaccines

Cannabidiol oils are equally or less effective at inhibiting certain cancer cell lines

Children in Melbourne family developed COVID-19 immune response after exposure to virus

Certain regions in the retina are more affected by Alzheimer's disease, shows study

Study highlights the disproportionate burden of COVID-19 among Black, Hispanic patients

SARS-CoV-2 was circulating in Italy before China recognized its existence

LOX plays a number of key roles in promoting skin and organ fibrosis in scleroderma

New multiplex assay can be used for epidemiological surveillance, management of COVID-19

New AHA COVID-19 CVD Registry details the disparities in care

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