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Simple, non-invasive tool obviates unnecessary surgery in patients with colorectal cancer

A blood RNA test predicts whether residual tumour cells remain in early-stage colon cancer patients and obviates unnecessary surgery.

6 Sep 2021

Georgia State researcher receives award to investigate the influence of environment on IBD

Dr. Michal Kuczma, a research assistant professor in the Institute for Biomedical Sciences at Georgia State University, has received a three-year, $270,000 Career Development Award from the Crohn's and Colitis Foundation to study environmental influences on gut microbiota, immunity and inflammation.

4 Sep 2021

Research confirms link between antibiotic use and increased risk of colon cancer

There is a clear link between taking antibiotics and an increased risk of developing colon cancer within the next five to ten years. This has been confirmed by researchers at Umeå University, Sweden, after a study of 40,000 cancer cases. The impact of antibiotics on the intestinal microbiome is thought to lie behind the increased risk of cancer.

1 Sep 2021

Maternal obesity during pregnancy may heighten the risk of colorectal cancer in adult offspring

Infants whose mothers were obese during pregnancy may have a heightened risk of developing colorectal cancer later in life, according to new research led by public health experts at The University of Texas Health Science Center at Houston.

27 Aug 2021

Restoring DAXX protein levels may prevent misfolding of rogue proteins known to drive Alzheimer's

For the first time, Penn Medicine researchers showed how restoring levels of the protein DAXX and a large group of similar proteins prevents the misfolding of the rogue proteins known to drive Alzheimer's and other neurodegenerative diseases, as well as certain mutations that contribute to cancers.

26 Aug 2021

The White Ribbon Project comes to UC Davis to acknowledge efforts in tackling lung cancer

Retired linebacker Chris Draft, who played on the 49ers and the Falcons as well as other NFL teams, was at UC Davis Comprehensive Cancer Center on Tuesday, Aug. 24, to acknowledge efforts by the cancer center to tackle lung cancer.

25 Aug 2021

Researchers identify mechanism for formation of rare colorectal cancer subtype

Researchers from Rutgers Cancer Institute of New Jersey, the state's only National Cancer Institute-designated Comprehensive Cancer Center, recently discovered a mechanism to explain what drives the formation of mucinous colorectal adenocarcinoma (MAC), a rare subtype of colorectal cancer (CRC), and has also identified the genes responsible for the regulation of this mechanism.

25 Aug 2021

Pericentromeric noncoding RNA provokes inflammatory gene expression in senescence and cancer

Research from the Cancer Institute at the Japanese Foundation for Cancer Research (JFCR), which was published today (August 23, at 3 pm US ET) in the leading international scientific journal Proceedings of the National Academy of Sciences of the United States of America, reveals that noncoding RNA derived from pericentromeric repetitive sequences provokes inflammatory gene expression in senescence and cancer.

24 Aug 2021

Antihypertensives may improve survival for patients with colorectal cancer

Common blood-pressure drugs may improve survival for patients with colorectal cancer, a new study suggests.

19 Aug 2021

Dysregulation of innate lymphoid cells drives colon cancer progression and immunotherapy resistance

An immune cell subset called innate lymphoid cells (ILC3s) protects against colorectal cancer, in part by helping to maintain a healthy dialogue between the immune system and gut microbes, according to a new study led by researchers at Weill Cornell Medicine and NewYork-Presbyterian. The finding opens the door to new strategies for treating this type of cancer.

17 Aug 2021

Vitamin D intake associated with lower risk of developing young-onset colorectal cancer

Consuming higher amounts of Vitamin D – mainly from dietary sources – may help protect against developing young-onset colorectal cancer or precancerous colon polyps, according to the first study to show such an association.

17 Aug 2021

Two-arm molecule can deplete cancer-protecting cells to promote immune responses against tumors

A two-arm molecule can effectively deplete cancer-protecting cells inside tumors, allowing the immune system to fight off tumors without becoming overactive. The finding, published online in Science Translational Medicine, could lead to new types of cancer immunotherapies.

11 Aug 2021

UC Davis epidemiologist turns to colleagues for cancer care

Brad Pollock knows a lot about cancer. In addition to his appointments as chair of the UC Davis Public Health Sciences Department and associate dean for public health sciences, Pollock is an expert in cancer epidemiology, including the study of what causes cancer, how it spreads and cancer prevention.

11 Aug 2021

Study explains how the ‘first brain’ works in the gut

New research explains how the nervous system in the gut causes propulsion along the gut, highlighting similar behavior to other neural networks in the brain and spinal cord.

11 Aug 2021

Study investigates the role of eIF4A3 protein in the growth of cancer cells

For a cell to grow and divide, it needs to produce new proteins. This also applies to cancer cells. In a new study published today in Science Advances, researchers at Karolinska Institutet in Sweden have investigated the protein eIF4A3 and its role in the growth of cancer cells.

4 Aug 2021

Discovery may enable the development of new therapies to kill aggressive cancer cells

Vanderbilt faculty and researchers are looking for the "Achilles' heel" of the cancer cells that survive initial chemotherapy.

3 Aug 2021

Newly identified genetic mutation causes rare, early onset inflammatory bowel disease

Johns Hopkins Medicine researchers, in collaboration with national and international researchers, have identified a genetic mutation in a small number of children with a rare type of inflammatory bowel disease.

30 Jul 2021

Study may help refocus research efforts on adolescent and young adult cancer survivorship

Survival rates for adolescents and young adults diagnosed with cancer have varied considerably depending on cancer type.

26 Jul 2021

Intestinal organoids demonstrate variability in SARS-CoV-2 susceptibility

Three-dimensional organoid structures grown in the lab allow deeper, almost in situ investigation of a biological system, without the use of living animals. In a paper recently uploaded to the preprint server bioRxiv*, organoids generated from human specimens are utilized to investigate the way in which SARS-CoV-2 interacts with the numerous cells of the intestinal epithelium, finding great heterogeneity in the susceptibility of the organoids and the cells within to infection.

21 Jul 2021

IgA deficiency results in substantial intestinal inflammation, study reveals

While researchers have known for years that immunoglobulin A (IgA) is important for gut health, it has remained unclear exactly what role it plays in preventing infection and disease. But now, researchers from Japan have found that eliminating IgA disrupts the balance of the intestinal ecosystem, making it susceptible to disease.

20 Jul 2021

Colon News and Research

Simple, non-invasive tool obviates unnecessary surgery in patients with colorectal cancer

Georgia State researcher receives award to investigate the influence of environment on IBD

Research confirms link between antibiotic use and increased risk of colon cancer

Maternal obesity during pregnancy may heighten the risk of colorectal cancer in adult offspring

Restoring DAXX protein levels may prevent misfolding of rogue proteins known to drive Alzheimer's

The White Ribbon Project comes to UC Davis to acknowledge efforts in tackling lung cancer

Researchers identify mechanism for formation of rare colorectal cancer subtype

Pericentromeric noncoding RNA provokes inflammatory gene expression in senescence and cancer

Antihypertensives may improve survival for patients with colorectal cancer

Dysregulation of innate lymphoid cells drives colon cancer progression and immunotherapy resistance

Vitamin D intake associated with lower risk of developing young-onset colorectal cancer

Two-arm molecule can deplete cancer-protecting cells to promote immune responses against tumors

UC Davis epidemiologist turns to colleagues for cancer care

Study explains how the ‘first brain’ works in the gut

Study investigates the role of eIF4A3 protein in the growth of cancer cells

Discovery may enable the development of new therapies to kill aggressive cancer cells

Newly identified genetic mutation causes rare, early onset inflammatory bowel disease

Study may help refocus research efforts on adolescent and young adult cancer survivorship

Intestinal organoids demonstrate variability in SARS-CoV-2 susceptibility

IgA deficiency results in substantial intestinal inflammation, study reveals

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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