Statin News and Research

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Statins are drugs used to lower cholesterol. Your body needs some cholesterol to work properly. But if you have too much in your blood, it can stick to the walls of your arteries, narrowing or even blocking them.

Researchers identify gut bacteria bile acids linked to effectiveness of statin drugs in lowering cholesterol

Statins can be effective at lowering cholesterol, but they have a perplexing tendency to work for some people and not others. Gut bacteria may be the reason.

14 Oct 2011

Statins hold promise against traumatic brain injury

Older patients who happened to have been taking cholesterol-lowering statin drugs when admitted to the hospital with serious head injuries were 76 percent more likely to survive than those not taking the drugs, according to results of a Johns Hopkins study.

11 Oct 2011

Merck’s diabetes combo pill gets FDA nod

The U.S. Food and Drug Administration (FDA) has approved Merck & Co.’s Juvisync diabetes drug, a combination pill for type 2 diabetes. Juvisync combines two Merck drugs already on the market, 1) glucose-lowering Januvia (Sitagliptin) medication and 2) cholesterol-lowering Zocor (Simvastatin).

10 Oct 2011

Merck receives FDA approval for JUVISYNC to treat type 2 diabetes

Merck, known as MSD outside the United States and Canada, announced today that the U.S. Food and Drug Administration (FDA) has approved JUVISYNC(sitagliptin and simvastatin), a new treatment for type 2 diabetes that combines the glucose-lowering medication sitagliptin, the active component of JANUVIA (sitagliptin), with the cholesterol-lowering medication ZOCOR.

10 Oct 2011

First combination drug to treat type 2 diabetes and high cholesterol receives FDA approval

The U.S. Food and Drug Administration today approved Juvisync (sitagliptin and simvastatin), a fixed-dose combination (FDC) prescription medication that contains two previously approved medicines in one tablet for use in adults who need both sitagliptin and simvastatin.

7 Oct 2011

Research roundup: Health disparities; Prescription drug abuse in Medicare Part D; Medicaid's role for HIV patients

Achieving Equity In Health -- This policy brief examines the outlining factors that cause disparities in the health care system and focuses on the October issue of the journal, which is devoted to research on the subject.

7 Oct 2011

Valeant's colesevelam New Drug Submission for hypercholesterolemia receives Canadian approval

Valeant Pharmaceuticals International, Inc. announced that its wholly owned subsidiary, Valeant International (Barbados) SRL, has received notice that the New Drug Submission for colesevelam hydrochloride (colesevelam), an oral bile acid sequestrant for hypercholesterolemia, has been approved by the Canadian regulatory authority Health Canada.

28 Sep 2011

Lovastatin appears to be safe, effective for children with neurofibromatosis type 1

Researchers at Children's National Medical Center have found that a cholesterol-lowering statin drug appears to be safe in children with neurofibromatosis type 1 (NF1) and may improve learning disabilities, including verbal and nonverbal memory.

28 Sep 2011

Alnylam commences ALN-PCS Phase I trial in severe hypercholesterolemia

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today that it has initiated dosing in its Phase I clinical trial with ALN-PCS, an RNAi therapeutic targeting proprotein convertase subtilisin/kexin type 9, or PCSK9, for the treatment of severe hypercholesterolemia.

27 Sep 2011

Six ways to prevent coronary artery disease

In honor of National Cholesterol Education Month, Hotze Health & Wellness Center (HHWC) is encouraging both men and women to take a proactive role in healthy aging, specifically heart disease prevention. HHWC is advocating effective measures to prevent heart attacks and is shedding new light on cholesterol myths and the dangers of cholesterol-lowering (statin) drugs.

23 Sep 2011

Researchers use MRI and PET/CT to assess safety, efficacy of heart drug dalcetrapib

Researchers from Mount Sinai School of Medicine have for the first time used several imaging techniques to prove the efficacy of a promising new treatment for atherosclerosis—the build-up of plaque in artery walls that can lead to a heart attack.

13 Sep 2011

Heart attack patients with psoriasis more likely to die from cardiovascular disease

Heart attack patients with psoriasis are 26 per cent more likely to die from cardiovascular disease, or suffer from recurrent heart attacks or strokes, and are 18 per cent more likely to die from all causes than those without the inflammatory skin disease.

12 Sep 2011

Study shows link between laughter and vascular health

Watching a funny movie or sitcom that produces laughter has a positive effect on vascular function and is opposite to that observed after watching a movie that causes mental stress according to research conducted at the University of Maryland School of Medicine in Baltimore, Maryland.

29 Aug 2011

EAS/ESC develops new dyslipidaemias guidelines

Clinicians should aim for comprehensive lipid control using lifestyle as a first step and tailoring treatment to patients. Lifestyle interventions, including stopping smoking, improving diet, exercising sufficiently and moderate alcohol consumption, should be the crucial first step for managing lipids in all patients.

29 Aug 2011

Statins protect people against death from respiratory illness, infections

The death rate among patients prescribed a statin in a major trial that ended in 2003 is still lower than those given a placebo, even though most participants in both groups have been taking statins ever since. ASCOT, the Anglo-Scandinavian Cardiac Outcomes Trial, was stopped early because the statin was so effective at preventing heart attacks and strokes, but a new analysis has shown that eight years on, the most significant difference between the groups is a reduction in deaths from infection and respiratory illness.

29 Aug 2011

Foods that can reduce cholesterol

At present those with cholesterol are prescribed cholesterol lowering drugs like statins and a diet that cuts out foods high in saturated fat. New research shows that some foods may help to lower cholesterol.

26 Aug 2011

Simvastatin may reduce spinal cord damage from ischemia/reperfusion injury

The cholesterol-lowering drug simvastatin appears to reduce spinal cord injury caused by oxygen deprivation in experimental animals, according to a study in the September issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society.

24 Aug 2011

Calcium scores and heart disease risk, experts debate

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22 Aug 2011

Statin therapy may not be appropriate for certain patients at risk for stroke

For many patients, cholesterol-lowering statin drugs can reduce the risk of strokes as well as heart attacks.

20 Aug 2011

High levels of calcium in coronary arteries increase risk of stroke, heart attack

The presence of calcium in coronary arteries is a much better predictor of heart attack and stroke than C-reactive protein among people with normal levels of LDL cholesterol, according to a study of more than 2,000 people led by a Johns Hopkins heart specialist.

19 Aug 2011

Statin News and Research

Further Reading

Researchers identify gut bacteria bile acids linked to effectiveness of statin drugs in lowering cholesterol

Statins hold promise against traumatic brain injury

Merck’s diabetes combo pill gets FDA nod

Merck receives FDA approval for JUVISYNC to treat type 2 diabetes

First combination drug to treat type 2 diabetes and high cholesterol receives FDA approval

Research roundup: Health disparities; Prescription drug abuse in Medicare Part D; Medicaid's role for HIV patients

Valeant's colesevelam New Drug Submission for hypercholesterolemia receives Canadian approval

Lovastatin appears to be safe, effective for children with neurofibromatosis type 1

Alnylam commences ALN-PCS Phase I trial in severe hypercholesterolemia

Six ways to prevent coronary artery disease

Researchers use MRI and PET/CT to assess safety, efficacy of heart drug dalcetrapib

Heart attack patients with psoriasis more likely to die from cardiovascular disease

Study shows link between laughter and vascular health

EAS/ESC develops new dyslipidaemias guidelines

Statins protect people against death from respiratory illness, infections

Foods that can reduce cholesterol

Simvastatin may reduce spinal cord damage from ischemia/reperfusion injury

Calcium scores and heart disease risk, experts debate

Statin therapy may not be appropriate for certain patients at risk for stroke

High levels of calcium in coronary arteries increase risk of stroke, heart attack

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Automating research - solutions and best practices

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