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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Scientists find link between colitis and colon cancer

Lingering inflammation in the colon is a known risk factor for colorectal cancer and now scientists report one way it resets the stage to enable this common and often deadly cancer.

14 Jan 2019

Researchers repurpose gene-editing tool CRISPR to develop better antibiotics

A University of Wisconsin-Madison researcher and his collaborators at the University of California, San Francisco have repurposed the gene-editing tool CRISPR to study which genes are targeted by particular antibiotics, providing clues on how to improve existing antibiotics or develop new ones.

11 Jan 2019

CRISPR-Cas9 circular permutants can sense and respond to viral proteases

Using a technique called circular permutation, researchers at the University of California Berkeley have created a new suite of Cas9 variants called Cas9-CPs, which will simplify design of Cas9-fusion proteins for diverse applications beyond simple DNA cutting, such as base editing and epigenetic modifications.

11 Jan 2019

Steady-state CD spectroscopy is a major structural tool in (bio)chemical analysis

In nature, certain molecules with the same chemical composition, can exist in two different shapes that are mirrors images of each other, much like our hands.

11 Jan 2019

Study shows an unusual mechanism could have thwart the invasion of human genome by junk DNA

In the January 7th edition of Communications Biology, researchers at InsideOutBio argue that an unusual form of DNA with a reverse twist may have helped thwart the invasion of the human genome by junk DNA.

11 Jan 2019

Novel biomarker links tumor progression to genome instability

Our DNA is under constant attack. The delicate molecule that contains our genetic information is extremely vulnerable to everything from environmental agents, such as radiation, to the chemicals in the air we breathe and the food we eat.

10 Jan 2019

New strategy may prevent spread of drug resistance

Spotless surfaces in hospitals can hide bacteria that rarely cause problems for healthy people but pose a serious threat to people with weakened immune systems.

10 Jan 2019

Unusual molecular regulatory mechanism discovered in unicellular parasites

Researchers of the University of Bern have discovered a new molecular regulatory mechanism in unicellular parasites which has never before been observed.

10 Jan 2019

New method to speed up genetic diagnosis of Huntington’s disease

Elongated segments of DNA cause Huntington's disease and certain other disorders of the brain. Researchers funded by the SNSF have developed a method to determine the length of the mutated genes quickly and easily.

10 Jan 2019

Aggressive prostate cancer linked to hereditary breast cancer, confirms study

Aggressive prostate cancer, one of the leading causes of cancer deaths in men, is associated with BRCA2 mutations, which are also linked to hereditary breast cancer, ovarian cancer and pancreas cancer, among others.

10 Jan 2019

Mapping a person's genetic makeup can help save billions each year in health costs

A UniSA scientist has called for Australia to embrace pharmacogenetic (PGx) testing to deliver medication more effectively and slash around $2.4 billion wasted each year through unsafe and ineffective drug prescriptions.

9 Jan 2019

Schizophrenia patients have higher levels of antibodies against Epstein-Barr virus, study shows

New research from Johns Hopkins Medicine and Sheppard Pratt Health System shows that people in the study with schizophrenia also have higher levels of antibodies against the Epstein-Barr virus (EBV), a herpes virus that causes infectious mononucleosis, so-called mono.

9 Jan 2019

FDA approves initiation of first-in-human trial of DNA-encoded monoclonal antibody

The Wistar Institute, along with partners Penn Medicine and Inovio Pharmaceuticals, Inc., announce that the FDA has approved the initiation of a first-in-human clinical trial investigating the safety and tolerability of a novel synthetic DNA-encoded monoclonal antibody therapeutic technology for the prevention of Zika virus infection.

9 Jan 2019

Researchers identify and overcome barrier in CRISPR gene editing to treat muscular dystrophy

The gene editing technique known as CRISPR is a revolutionary approach to treating inherited diseases. However, the tool has yet to be used to effectively treat long-term, chronic conditions.

9 Jan 2019

Study offers new insight on mechanism underlying control of gene expression

Researchers have provided new insight on the mechanism underlying the control of gene expression in all living organisms, according to a study published today in eLife.

8 Jan 2019

New molecular engineering method improves precision of biomarker analysis

Researchers from the University of Helsinki in cooperation with the University of Tartu, Competence Centre on Health Technologies from Estonia, and the Karolinska Institute, published an article in Nature's partner journal Genomic Medicine in which they present Targeted Allele Counting by sequencing along with several of its potential applications.

8 Jan 2019

DNA News and Research

Further Reading

Scientists find link between colitis and colon cancer

Researchers repurpose gene-editing tool CRISPR to develop better antibiotics

CRISPR-Cas9 circular permutants can sense and respond to viral proteases

Steady-state CD spectroscopy is a major structural tool in (bio)chemical analysis

Study shows an unusual mechanism could have thwart the invasion of human genome by junk DNA

Novel biomarker links tumor progression to genome instability

New strategy may prevent spread of drug resistance

Unusual molecular regulatory mechanism discovered in unicellular parasites

New method to speed up genetic diagnosis of Huntington’s disease

Aggressive prostate cancer linked to hereditary breast cancer, confirms study

Mapping a person's genetic makeup can help save billions each year in health costs

Schizophrenia patients have higher levels of antibodies against Epstein-Barr virus, study shows

FDA approves initiation of first-in-human trial of DNA-encoded monoclonal antibody

Researchers identify and overcome barrier in CRISPR gene editing to treat muscular dystrophy

Study offers new insight on mechanism underlying control of gene expression

New molecular engineering method improves precision of biomarker analysis

PAC1R mutation in children with autism may be linked to severity of social problems

Johns Hopkins researchers identify new marker for early detection of colorectal cancers

A Light Source in Quantitative Analysis: What Role Does it Play?

New bioinspired material interacts with surrounding tissues to promote wound healing

eBook: A guide to RNA sequencing eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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