Chromosome 7 News and Research

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Humans normally have 46 chromosomes in each cell, divided into 23 pairs. Two copies of chromosome 7, one copy inherited from each parent, form one of the pairs. Chromosome 7 spans about 159 million DNA building blocks (base pairs) and represents more than 5 percent of the total DNA in cells.

Identifying genes on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 7 likely contains about 1,150 genes.

Genes on chromosome 7 are among the estimated 20,000 to 25,000 total genes in the human genome.

New study identifies key role for particular gene in 16p11.2 deletion syndrome

In a new study of one of the most common genetic causes of autism, neuroscientists at MIT's Picower Institute for Learning and Memory have identified a specific molecular mechanism that appears to undermine the ability of neurons in affected mice to properly incorporate changes driven by experience.

20 Mar 2018

Genetic link to insomnia found

A new study has found certain genes that predispose a person to develop insomnia or sleep problems. This was one of the largest genome wide studies undertaken on insomnia. The study led by psychiatrist Murray Stein from the University of California San Diego was published in the latest issue of the journal Molecular Psychiatry.

13 Mar 2018

OGT launches new, easy-to-use Cytocell FISH probes website

Oxford Gene Technology, The Molecular Genetics Company, has launched a new version of its Cytocell fluorescence in situ hybridization probes website - designed to provide a wealth of information and advice, offer refined functionality, and be easy-to-use.

From Oxford Gene Technology 8 Mar 2018

UNIGE researchers discover why premature cell division promotes tumor formation

The accumulation of mutations in the human genome is at the origin of cancers, as well as the development of resistance to treatments. The Cyclin E and Myc genes are active in the control of cell division.

28 Feb 2018

ASU researchers uncover crucial step in telomerase enzyme catalytic cycle

Can we stay young forever, or even recapture lost youth? Research from the laboratory of Professor Julian Chen in the School of Molecular Sciences at Arizona State University recently uncovered a crucial step in the telomerase enzyme catalytic cycle.

27 Feb 2018

Fathers maybe passing on ovarian cancer genes to their daughters

According to a team of researchers from the Roswell Park Cancer Institute, a new gene mutation could be responsible for ovarian cancers and this could be passed on from fathers to their daughters.

16 Feb 2018

Hints to aging lurk in fruit flies’ germline stem cells

Little hints of immortality are lurking in the stem cells of fruit flies. Stem cells that produce sperm use a genetic trick to stay perpetually young across generations, researchers at the University of Michigan Life Sciences Institute have discovered. Certain sections of the fruit fly genome get shorter with age. But remarkably, some reproductive cells can repair the shrinkage, the researchers report in the journal eLife.

13 Feb 2018

Next-generation ‘active genetics’ tool opens new horizons

In 2015, University of California San Diego biologists Ethan Bier and Valentino Gantz developed a breakthrough technology known as "active genetics," which results in parents transmitting a genetic trait to most of their offspring (instead of 50 percent receiving the trait under standard inheritance).

6 Feb 2018

Mitochondrial DNA may play more important role in metastatic cancer than previously thought

DNA found in the mitochondria may play a more significant role in metastatic cancer than originally thought.

6 Feb 2018

Study shows connection between genetic variants for ADHD and educational attainment

A study published in the February 2018 issue of the Journal of the American Academy of Child and Adolescent Psychiatry reports that five novel genetic variants associated with attention-deficit/hyperactivity disorder (ADHD) have been identified by exploiting genetic overlap between ADHD and educational attainment.

5 Feb 2018

Researchers move closer to solving puzzle of 15q13.3 microdeletion syndrome

Researchers are closer to solving the puzzle of a complex neurological condition called 15q13.3 microdeletion syndrome. Individuals with this condition are missing a small piece of chromosome 15 that usually contains six genes, but which one of the genes is responsible for the clinical characteristics of patients has not been clear.

2 Feb 2018

Free magnesium ions regulate chromosome shape, new tool shows

Japanese researchers report a new ion detector, MARIO. Using it, they show that changes in the intracellular concentration of free magnesium ions (Mg2+) is critical for the chromosome folding that must occur for cells to divide.

1 Feb 2018

Researchers use gene therapy that lengthens telomeres to cure pulmonary fibrosis in mice

Idiopathic pulmonary fibrosis is a potentially lethal disease associated with the presence of critically short telomeres, currently lacking effective treatment.

30 Jan 2018

Discovery may offer new therapeutic approach for kids with Prader-Willi syndrome

Stem cell researchers at UConn Health have reversed Prader-Willi syndrome in brain cells growing in the lab, findings they recently published in the Human Molecular Genetics.

27 Jan 2018

Small tweak to mammal's DNA can cause significant physical changes, study finds

The difference between webbed toes and distinct digits may be the result of not just genetic information, but of how the genes regulate that information. Researchers at the National Institute of Genetics, Research Organization of Information and Systems in Japan found that a small, non-specific tweak to a mammal's DNA can potentially cause specific and significant physical changes.

27 Jan 2018