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New antibody with SGN-35 drug produces remission in Hodgkin lymphoma

An antibody loaded with an anti-cancer agent produced complete or partial remissions in 38 percent of patients with relapsed or therapy-resistant Hodgkin lymphoma enrolled in a phase I clinical trial, investigators report in the Nov. 4 issue of the New England Journal of Medicine.

4 Nov 2010

Positive results from Lithera's LIPO-102 Phase IIb clinical study for abdominal fat reduction

Lithera, Inc. today announced positive results from a Phase IIb clinical study of LIPO-102, its novel injectable combination of salmeterol xinafoate (SX) and fluticasone propionate (FP) for selective, non-ablative fat reduction.

4 Nov 2010

Study links positive well-being to higher telomerase activity

Positive psychological changes that occur during meditation training are associated with greater telomerase activity, according to researchers at the University of California, Davis, and the University of California, San Francisco. The study is the first to link positive well-being to higher telomerase, an enzyme important for the long-term health of cells in the body.

4 Nov 2010

BioCurex files patent for synthetic peptide in RECAF test

BioCurex, Inc. today announced that it has filed a new patent within the Patent Cooperation Treaty, which presently includes 142 countries.

4 Nov 2010

Medicare reimbursement cuts lead to decline in unnecessary or inappropriate care

When Medicare policy changes led to reductions in reimbursement for hormonal treatment of prostate cancer, there was a sharp decline in its use among patients not likely to benefit from the treatment. But among patients for whom the therapy is clearly beneficial, doctors continued to prescribe it at the same rate, according to a new study.

4 Nov 2010

New cyber-database enables access to information on lymphedema

Lymphedema is a chronic condition that causes swelling of the limbs and affects physical, mental and social health. It commonly occurs in breast cancer survivors and is the second-most dreaded effect of treatment, after cancer recurrence. Every day, researchers throughout the world learn more about the condition and how it can be treated. Now, University of Missouri researchers are developing a place in cyberspace where relevant and timely information can be easily stored, searched, and reviewed from anywhere with the goal of improving health care through the availability of up-to-date, evidence-based research.

4 Nov 2010

Single injection of morphine to fight persistent pain reduces testosterone level: Research

A single injection of morphine to fight persistent pain in male rats is able to strongly reduce the hormone testosterone in the brain and plasma, according to a new paper published in Molecular Pain.

4 Nov 2010

Scientists discover gene variant that rewires brain's circuitry in neurological disorders

Many gene variants have been linked to autism, but how do these subtle changes alter the brain, and ultimately, behavior. Using a blend of brain imaging and genetic detective work, scientists at UCLA's David Geffen School of Medicine and Semel Institute for Neuroscience and Human Behavior are the first to illustrate how a gene variant tied to autism rewires the brain.

4 Nov 2010

Biogen Idec and Cardiokine terminate lixivaptan collaboration

Biogen Idec and Cardiokine, Inc. today announced that they have agreed to dissolve their collaboration on lixivaptan. The termination of the collaboration, which began in 2007, triggers the return of all rights to lixivaptan to Cardiokine.

4 Nov 2010

New simple blood test may help diagnose Niemann-Pick type C disease

A fatal genetic disorder that frequently takes years to diagnose may soon be detectable with a simple blood test, researchers at Washington University School of Medicine in St. Louis and the National Institutes of Health (NIH) report this week in Simple blood test may diagnose deadly Niemann-Pick type C disease.

4 Nov 2010

Alnylam third quarter revenue increases from $24.2 million to $27.7 million

Alnylam Pharmaceuticals, Inc. a leading RNAi therapeutics company, today reported its consolidated financial results for the third quarter ended September 30, 2010, and company highlights.

4 Nov 2010

One-third of breast cancer survivors rate breast-conserving treatments as fair

A third of breast cancer survivors who received the breast-conserving treatments lumpectomy and radiation rate the appearance of their post-treatment breast as only "fair" or "poor" in comparison to their untreated breast, according to a new University of Pennsylvania School of Medicine study that will be presented today at the 52nd Annual Meeting of the American Society for Radiation Oncology (ASTRO) in San Diego.

3 Nov 2010

Ingenuity Systems and Geospiza partner to enable seamless next-generation sequencing analysis workflow

Ingenuity® Systems, a leading provider of information solutions for life science researchers, and Geospiza, Inc., the market leading developer of laboratory management and genetic analysis software, today announced a collaboration to enable a seamless next-generation sequencing analysis workflow. The companies will integrate their software products, GeneSifter® and IPA®, to enable researchers to obtain deep biological insights from their project samples through a rapid and reliable workflow to analyze and visualize next-generation sequencing data.

3 Nov 2010

Harvard Bioscience third quarter revenue increases 26.0% to $26.5 million

Harvard Bioscience, Inc. a global developer, manufacturer, and marketer of a broad range of tools to advance life science research and regenerative medicine, today reported unaudited financial highlights for the three and nine months ended September 30, 2010.

From Harvard Bioscience 3 Nov 2010

Safeguard Scientifics third quarter aggregate revenue of partner companies increases 73% to $109.6 million

Safeguard Scientifics, Inc., a holding company that provides growth capital for entrepreneurial and innovative life sciences and technology companies, today announced that aggregate revenue of its partner companies for the three months ended September 30, 2010 was $109.6 million, up 73% from $63.4 million for the same partner companies in the same period of 2009.

3 Nov 2010

IU's cost-saving model of home-based care management for low-income older adults earns recognition

A model program developed at Indiana University to provide care to low-income older adults in their homes has earned recognition for its effective approach and cost-saving benefits in a leading national medical journal.

3 Nov 2010

Study examines factors that play a role in older adult's transition to disability, illnesses and injuries

In a study examining the factors that play a role in an older adult's transition to disability, intervening illnesses and injuries that led to hospitalization or activity restriction were associated with worsening functional ability, especially among those who were physically frail, according to a study in the November 3 issue of JAMA, a theme issue on aging.

3 Nov 2010

Diverse Surgeons Initiative addresses lack of minority surgeons in academic field

According to a report published in the October issue of the Journal of the American College of Surgeons, a grant-funded program tailored to provide advanced minimally invasive surgery skills to young, underrepresented minority surgeons, is helping address shortages of minority faculty members at US medical institutions.

3 Nov 2010

Immune Network to complete patient enrollment in Phase 2b imm01 trial for tuberculosis

Immune Network Ltd. a company in the business of discovery and development of immune-based therapies, today announced that patient enrollment will be completed next week for the company's future partner Immunitor's Phase 2b imm01 trial of V5 immunotherapy in 120 patients with tuberculosis.

3 Nov 2010

MSU awarded $4.2M to develop clinical research tools for osteopathic manipulative medicine study

A multidisciplinary team of Michigan State University researchers has been awarded $4.2 million to develop accurate clinical research tools for studying osteopathic manipulative medicine, a hands-on approach to the diagnosis and treatment of musculoskeletal disorders.

3 Nov 2010

Medicine News and Research

New antibody with SGN-35 drug produces remission in Hodgkin lymphoma

Positive results from Lithera's LIPO-102 Phase IIb clinical study for abdominal fat reduction

Study links positive well-being to higher telomerase activity

BioCurex files patent for synthetic peptide in RECAF test

Medicare reimbursement cuts lead to decline in unnecessary or inappropriate care

New cyber-database enables access to information on lymphedema

Single injection of morphine to fight persistent pain reduces testosterone level: Research

Scientists discover gene variant that rewires brain's circuitry in neurological disorders

Biogen Idec and Cardiokine terminate lixivaptan collaboration

New simple blood test may help diagnose Niemann-Pick type C disease

Alnylam third quarter revenue increases from $24.2 million to $27.7 million

One-third of breast cancer survivors rate breast-conserving treatments as fair

Ingenuity Systems and Geospiza partner to enable seamless next-generation sequencing analysis workflow

Harvard Bioscience third quarter revenue increases 26.0% to $26.5 million

Safeguard Scientifics third quarter aggregate revenue of partner companies increases 73% to $109.6 million

IU's cost-saving model of home-based care management for low-income older adults earns recognition

Study examines factors that play a role in older adult's transition to disability, illnesses and injuries

Diverse Surgeons Initiative addresses lack of minority surgeons in academic field

Immune Network to complete patient enrollment in Phase 2b imm01 trial for tuberculosis

MSU awarded $4.2M to develop clinical research tools for osteopathic manipulative medicine study

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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