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New fluorescent probe identifies cancer stem cells

Cells with stem-cell characteristics appear to be especially important in the formation and metastasis of tumors. Scientists have now developed a universal fluorescent probe for these "cancer stem cells". As reported in the journal Angewandte Chemie, this dye also selectively kills off the cells.

4 Apr 2018

Photoswitchable drugs may light the way to treat disease with fewer side effects

Side effects from drugs working in non-target locations within the body can cause debilitating symptoms, often resulting in patients stopping their course of treatment early.

4 Apr 2018

Visceral fat linked to shorter survival for women with kidney cancer

Belly fat affects the odds of women surviving kidney cancer but not men, according to a new study by researchers at Washington University School of Medicine in St. Louis.

4 Apr 2018

New insights into 100-year-old mystery open novel possibilities for breast cancer treatment

New insights into how cancer cells fuel their growth are opening novel possibilities for cancer treatment. A team of researchers at Baylor College of Medicine and Roswell Park Comprehensive Cancer Center has identified a long sought after connection between how cancer cells use the sugar glucose to generate energy - the Warburg pathway - and cancer growth.

3 Apr 2018

Ionizing radiation can reduce stiffness of tumor cell microenvironment

Nearly half of all cancer patients receive radiation therapy to curb the growth of malignant cells. But little is known about how ionizing radiation affects the extracellular matrix (ECM), a patchwork of proteins and other biomolecules that surrounds cells and plays a vital role in their shape, movement and signaling functions.

3 Apr 2018

FDA-approved drug for chemical abortion shows promise for treatment of vestibular schwannoma

Massachusetts Eye and Ear researchers have shown that mifepristone, a drug currently FDA-approved for chemical abortion, prevents the growth of vestibular schwannoma cells. This sometimes-lethal intracranial tumor typically causes hearing loss and tinnitus

3 Apr 2018

Researchers working to develop new system for early prostate cancer diagnosis

Researchers of the Universitat Politècnica de València and the Universidad de Granada, together with doctors from the Hospital Clínic Universitari de València are working on the development of a new system to help diagnose prostate cancer. The work being developed is part of the SICAP project.

3 Apr 2018

Gut bacteria may hold clues to predict effectiveness of cancer immunotherapies

The composition of bacteria in the gastrointestinal tract may hold clues to help predict which cancer patients are most apt to benefit from the personalized cellular therapies that have shown unprecedented promise in the fight against hard-to-treat cancers, according to new research from the Perelman School of Medicine at the University of Pennsylvania.

3 Apr 2018

Study uncovers mechanism causing chronic GVHD after bone marrow transplant

Allogeneic bone marrow transplant (BMT) is an essential treatment to cure patients with blood cancers such as leukemia. In patients who have undergone chemotherapy and radiation, a small number of cancer cells can remain in the bloodstream and allow the malignancy to recur.

3 Apr 2018

Computational biologists develop algorithm to align datasets with single-cell resolution

A team of computational biologists has developed an algorithm that can 'align' multiple sequencing datasets with single-cell resolution.

3 Apr 2018

Researchers identify 200 mutations in non-coding DNA that play role in cancer

Most of the human genome - 98 percent - is made up of DNA but doesn't actually encode genes, the recipes cells use to build proteins.

2 Apr 2018

Combined treatment prolongs survival in mouse models of malignant mesothelioma

Combined treatment with two cancer immunotherapy drugs - one a novel immune modulator and one that focuses and activates the antitumor immune response - significantly prolonged survival in mouse models of the aggressive cancer malignant mesothelioma.

2 Apr 2018

Researchers create new compound that appears to activate cancer-fighting T cells

Invariant natural killer T (iNKT) cells are powerful weapons our body's immune systems count on to fight infection and combat diseases like cancer, multiple sclerosis, and lupus. Finding ways to spark these potent cells into action could lead to more effective cancer treatments and vaccines.

2 Apr 2018

Molecular inhibitors found to arrest tumor cell proliferation in lung cancer and mesothelioma

Inhibition of the oncogenic kinase AKT, a key protein governing the cell cycle, was found to arrest cancer cell proliferation and triggered their programmed death by apoptosis.

2 Apr 2018

First-of-its-kind cancer drug effective in 93% of pediatric patients

A first-of-its-kind drug targeting a fused gene found in many types of cancer was effective in 93 percent of pediatric patients tested, researchers at UT Southwestern's Simmons Cancer Center announced.

30 Mar 2018

Cancers may be detected at smaller size in breasts with implants, study reveals

Breast augmentation with implants does not interfere with the ability to detect later breast cancers--in fact, cancers may be detected at a smaller size in breasts with implants, according to a study in the April issue of Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons.

29 Mar 2018

Genomic test effective for detecting Lynch syndrome in CRC patients

A single, upfront genomic test is more effective for detecting Lynch syndrome in colorectal cancer (CRC) patients than the traditional multiple, sequential testing approach, according to new clinical data reported by The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute.

29 Mar 2018

Tumor News and Research

New fluorescent probe identifies cancer stem cells

Photoswitchable drugs may light the way to treat disease with fewer side effects

Visceral fat linked to shorter survival for women with kidney cancer

New insights into 100-year-old mystery open novel possibilities for breast cancer treatment

Ionizing radiation can reduce stiffness of tumor cell microenvironment

FDA-approved drug for chemical abortion shows promise for treatment of vestibular schwannoma

Researchers working to develop new system for early prostate cancer diagnosis

Gut bacteria may hold clues to predict effectiveness of cancer immunotherapies

Study uncovers mechanism causing chronic GVHD after bone marrow transplant

Computational biologists develop algorithm to align datasets with single-cell resolution

Researchers identify 200 mutations in non-coding DNA that play role in cancer

Combined treatment prolongs survival in mouse models of malignant mesothelioma

Researchers create new compound that appears to activate cancer-fighting T cells

Molecular inhibitors found to arrest tumor cell proliferation in lung cancer and mesothelioma

First-of-its-kind cancer drug effective in 93% of pediatric patients

Cancers may be detected at smaller size in breasts with implants, study reveals

Genomic test effective for detecting Lynch syndrome in CRC patients

Salk scientists discover protein that 'turns off' uncontrolled liver cancer growth

New technology using SLAM and AR enables doctors to perform more accurate biopsy

Researchers develop novel approach to fighting ovarian cancer

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Exploring the G:Box and for high-quality imaging

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