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Health Affairs recognizes U-M leadership in implementing Value-Based Insurance Design

Value-Based Insurance Design - a concept created at the University of Michigan and incorporated in the nation's new health care reform law - is the focus of an upcoming national policy journal.

3 Nov 2010

Electrophysiology Innovations Congress EP Innovations 2010 to highlight treatment of atrial fibrillation

The North American Center for Continuing Medical Education, LLC , in partnership with HMP Communications, LLC, publisher of EP Lab Digest, today announced several key sessions on the treatment of atrial fibrillation at the upcoming Electrophysiology Innovations Congress EP Innovations 2010, the world's premier annual electrophysiology meeting, to be held December 9-11, 2010, at the Washington Hilton in Washington, DC.

3 Nov 2010

Systagenix introduces world's first rapid point of test in wound care

Innovation doesn't come easy" says Steve Atkinson, Systagenix CEO "and neither do great brands, yet our team have been responsible for many innovations within this field over the last four decades. We are now introducing the world's first rapid point of care test in wound care to help clinicians choose the most appropriate dressings and therapies for their patients and monitor their efficacy over time.

3 Nov 2010

Amgen outlines key recommendations for implementing approval pathway for biosimilars

Amgen Senior Vice President of Research and Development Joe Miletich, M.D., Ph.D., will urge members of a U.S. Food and Drug Administration (FDA) panel charged with implementing a pathway for biosimilars to establish approval standards that ensure patient safety and follow a science-based approach.

3 Nov 2010

Study reveals a potential target for treating brain trauma

Brain damage continues to develop and evolve for months after a traumatic brain injury (TBI), revealing a potential target for treatments to improve brain trauma, new research led by the University of Melbourne, Australia has found.

3 Nov 2010

Study finds infertility treatment does not increase risk of cerebral palsy in IVF/ICSI children

Doctors have known for some time that children born after fertility treatments such as in vitro fertilisation (IVF) or intracytoplasmic sperm injection (ICSI) are at increased risk of cerebral palsy. However, it was not known whether this risk was due to the treatment itself, the higher frequency of preterm or multiple births, or a mechanism associated with couples' underlying infertility.

3 Nov 2010

CR4354 antibody uses crosslinking mechanism to neutralize West Nile virus

Researchers have learned the structure that results when an antibody binds to the West Nile virus, neutralizing the virus by locking up its infection mechanism. The information could help scientists develop a vaccine against the mosquito-borne disease.

3 Nov 2010

POZEN’s therapeutic development programs qualified to receive federal grant under PPACA

POZEN Inc., a pharmaceutical company committed to transforming medicine that transforms lives, today announced that three of the Company's therapeutic development programs, VIMOVO (naproxen / esomeprazole magnesium) (formerly PN400), PA32540 and PA65020, qualified to receive federal grant funding under The Patient Protection and Affordable Care Act.

3 Nov 2010

Tolerx establishes Scientific Advisory Board to advance type 1 diabetes study

Tolerx, Inc., a biopharmaceutical company developing novel therapies to treat autoimmune diseases and cancer by modulating T cell activity, announced today that it has established a Scientific Advisory Board to help advance the company's research and clinical studies in type 1 diabetes.

3 Nov 2010

Study: Illnesses and injuries that restrict activity linked to worsening functional ability in older adults

A study by Yale School of Medicine researchers reveals that the illnesses and injuries that can restrict the activity of older adults or land them in the hospital are linked to worsening functional ability, especially among those who are physically frail. The report appears in JAMA's November 3 theme issue on aging.

3 Nov 2010

Immunomedics product candidates, technologies receive recognition from QTDP program

Immunomedics, Inc. a biopharmaceutical company primarily focused on the development of monoclonal, antibody-based products for the targeted treatment of cancer, autoimmune and other serious diseases, today announced that all 12 applications from the Company were certified by the Internal Revenue Service of the Department of Treasury as qualified investments in accordance with the Qualifying Therapeutic Discovery Project (QTDP) program under section 48D of the Internal Revenue Code. As a result, the Company will receive an aggregate cash award of $2.9 million.

3 Nov 2010

New mouse model confirms mutation of beta-synuclein protein promotes neurodegeneration

A team of scientists from Japan and the University of California, San Diego School of Medicine have created a new mouse model that confirms that mutations of a protein called beta-synuclein promote neurodegeneration. The discovery creates a potential new target for developing treatments of diseases like Parkinson's and Alzheimer's.

3 Nov 2010

Roux-en-Y gastric bypass surgery effective for morbid obesity

Gastric bypass surgery decreases the preference for sweet-tasting substances in obese rats, a study finding that could help in developing safer treatments for the morbidly obese, according to Penn State College of Medicine researchers.

3 Nov 2010

Researchers discover FoxO1 protein interacts with macrophages to promote inflammatory response

Researchers at the University of California, San Diego School of Medicine have discovered that a multi-tasking protein called FoxO1 has another important but previously unknown function: It directly interacts with macrophages, promoting an inflammatory response that can lead to insulin resistance and diabetes. Contrarily, it also generates a negative feedback loop that can limit damage from excessive inflammation.

3 Nov 2010

Johns Hopkins assists with establishment of Malaysia's first private graduate medical school and teaching hospital

The Johns Hopkins University, the Johns Hopkins University School of Medicine, Johns Hopkins Medicine International (JHI), the international arm of Johns Hopkins Medicine in Baltimore, USA, and Academic Medical Centre Sdn Bhd, subsidiary of Chase Perdana Sdn Bhd, a Kuala Lumpur-based private development corporation, and an associate company of Turiya Sdn Bhd, have signed an agreement to help Malaysia develop its first fully integrated private four-year graduate medical school and teaching hospital.

3 Nov 2010

Hyperion HPN-100 phase III pivotal study for urea cycle disorders meets primary endpoint

Hyperion Therapeutics, Inc. today announced that the Company's phase III pivotal study of glycerol phenylbutyrate (HPN-100), an investigational drug for the treatment of urea cycle disorders (UCDs), met its primary endpoint. The non-inferiority study, conducted under a Special Protocol Assessment (SPA) granted by the U.S. Food and Drug Administration (FDA) in June 2009, evaluated the ammonia control of glycerol phenylbutyrate as compared to sodium phenylbutyrate (BUPHENYL®).

3 Nov 2010

Staff member of U.S. preventive services task force quits over cancelled meeting

A member of the support staff for the United States Preventive Services Task Force has quit over the cancellation of a meeting scheduled for today and tomorrow at which the task force was due to vote on the controversial issue of prostate-cancer screening.

3 Nov 2010

Mouse study indicates black raspberries can prevent colorectal cancer

Black raspberries are highly effective in preventing colorectal tumors in two mouse models of the disease, according to a University of Illinois at Chicago study. The findings are published in the November issue of Cancer Prevention Research.

3 Nov 2010

Researchers reveal molecular structure of blood-clotting enzyme

Using state-of-the-art robotic and x-ray crystallographic equipment, researchers at Saint Louis University have revealed for the first time the molecular structure of the zymogen, or inactive, form of a blood-clotting enzyme.

3 Nov 2010

Nile announces results of CD-NP Phase 2 study in renally compromised ADHF patients

Nile Therapeutics, Inc. a biopharmaceutical company focused on the development of novel therapeutics for cardiovascular disease, today announced results of its Phase 2 study evaluating its lead compound CD-NP in patients with acute decompensated heart failure (ADHF) and mild to moderate renal insufficiency. Study results demonstrated that multiple doses were characterized as well tolerated with favorable drug activity in this acute patient population.

3 Nov 2010

Medicine News and Research

Health Affairs recognizes U-M leadership in implementing Value-Based Insurance Design

Electrophysiology Innovations Congress EP Innovations 2010 to highlight treatment of atrial fibrillation

Systagenix introduces world's first rapid point of test in wound care

Amgen outlines key recommendations for implementing approval pathway for biosimilars

Study reveals a potential target for treating brain trauma

Study finds infertility treatment does not increase risk of cerebral palsy in IVF/ICSI children

CR4354 antibody uses crosslinking mechanism to neutralize West Nile virus

POZEN’s therapeutic development programs qualified to receive federal grant under PPACA

Tolerx establishes Scientific Advisory Board to advance type 1 diabetes study

Study: Illnesses and injuries that restrict activity linked to worsening functional ability in older adults

Immunomedics product candidates, technologies receive recognition from QTDP program

New mouse model confirms mutation of beta-synuclein protein promotes neurodegeneration

Roux-en-Y gastric bypass surgery effective for morbid obesity

Researchers discover FoxO1 protein interacts with macrophages to promote inflammatory response

Johns Hopkins assists with establishment of Malaysia's first private graduate medical school and teaching hospital

Hyperion HPN-100 phase III pivotal study for urea cycle disorders meets primary endpoint

Staff member of U.S. preventive services task force quits over cancelled meeting

Mouse study indicates black raspberries can prevent colorectal cancer

Researchers reveal molecular structure of blood-clotting enzyme

Nile announces results of CD-NP Phase 2 study in renally compromised ADHF patients

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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