Bioinformatics News and Research

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Bioinformatics is the application of information techniques for the storage, retrieval, and analysis of large quantities of biological data.

Researchers receive $2.95 million grant to create improved diagnostics for worm infections

Global campaigns to eliminate two tropical parasitic worm infections have been hindered by a lack of good diagnostic tools.

7 Jan 2021

Researchers develop a gene signature for predicting survival in patients with peritoneal carcinomatosis

Researchers from The University of Texas MD Anderson Cancer Center who profiled more than 45,000 individual cells from patients with peritoneal carcinomatosis (PC), a specific form of metastatic gastric cancer, defined the extensive cellular heterogeneity and identified two distinct subtypes correlated with patient survival.

4 Jan 2021

Researchers discover protein crucial to T cell metabolism and anti-tumor immune response

Researchers at The University of Texas MD Anderson Cancer Center have discovered that a protein called NF-kappa B-inducing kinase (NIK) is essential for the shift in metabolic activity that occurs with T cell activation, making it a critical factor in regulating the anti-tumor immune response.

4 Jan 2021

Six clearly distinguishable subtypes of prediabetes identified

All prediabetes is not the same: in people in the preliminary stages of type 2 diabetes, there are six clearly distinguishable subtypes, which differ in the development of the disease, diabetes risk, and the development of secondary diseases.

4 Jan 2021

Certain aquatic insects can forewarn against possible outbreaks of diarrheal disease, shows study

Chironomids, a group of aquatic insects closely related to mosquitoes, act as natural reservoirs of disease-causing cholera bacteria and can forewarn against possible outbreaks of the diarrhoeal disease, a new study suggests

4 Jan 2021

A handy reference on pollution

Pollution is one among the serious cases which needs to be taken care of. Pollution is broadly classified as air, land, water and earth pollution.

28 Dec 2020

Immunologic modeling of COVID-19 severity and chronicity

In a new study by researchers at Universidad de Costa Rica and other institutions, a bioinformatics approach is used to determine whether Chronic COVID-19 (CC) might have a distinct immunologic signature compared to the mild to moderate (MM) or the severe/critical COVID-19.

24 Dec 2020

SARS-CoV-2 infection shown to reduce the expression of vitamin D pathway components

A recent computational study from India implicated a dysregulated vitamin D pathway in the pathobiology of the infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – and opened the door for experimental validation of these observations.

23 Dec 2020

SARS-CoV-2 mutations may evade T cell immunity

A potentially disturbing new study suggests that SARS-CoV-2 may be undergoing strategic mutations that affect the host immune capacity to recognize and combat the pathogen via T effector cells.

23 Dec 2020

Novel 3D maps show how genes interact in several types of immune cells

The COVID-19 pandemic has highlighted how our small genetic differences can have a tremendous effect on how our bodies respond to disease.

22 Dec 2020

£6.7m awarded to find new ways to improve prevention, diagnosis and treatment of diseases

Barts Life Sciences - a partnership between Barts Health NHS Trust and Queen Mary University of London - has been awarded £6.7m by Barts Charity to research new ways to improve the prevention, diagnosis and treatment of a variety of diseases.

18 Dec 2020

Researchers investigate microbiome-mediated therapies for aging and health span

Texas Biomedical Research Institute Associate Professor Corinna Ross, PhD, is a principal investigator on a $3.38 million National Institutes of Health multi-investigator grant to study "microbiome-mediated therapies for aging and healthspan" in marmosets, which are small monkeys native to South America and are becoming increasingly more important in aging and infectious disease research.

18 Dec 2020

Researchers discover cells responsible for resistance to T-ALL treatment

T-cell acute lymphoblastic leukemia (T-ALL) is a cancer of the blood that affects mainly children, but also less frequently adults. In adults, although the response to treatment might be initially positive, relapses are common and have a poor prognosis.

17 Dec 2020

Researchers identify key gene necessary for cells to consume and destroy viruses

A team led by UT Southwestern researchers has identified a key gene necessary for cells to consume and destroy viruses. The findings, reported online today in Nature, could lead to ways to manipulate this process to improve the immune system's ability to combat viral infections, such as those fueling the ongoing COVID-19 pandemic.

17 Dec 2020

A new approach to identify genomic regions in our brain that contribute to make us human

With only 1% difference, the human and chimpanzee protein-coding genomes are remarkably similar.

16 Dec 2020

Scientists identify new Salmonella proteins

Salmonella are bacteria that can cause food poisoning with severe diarrhea. If they penetrate from the intestine into the blood system, this can lead to sepsis, life-threatening inflammatory reactions in the entire organism.

16 Dec 2020

SARS-CoV-2 unique deletion variants found in clinical specimens

While participating in the SPHERES Consortium project, US researchers sequenced 2,726 clinical patient specimens gathered in March 2020 and identified eight unique ORF7a deletion variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Their results are currently available on the bioRxiv* preprint server.

15 Dec 2020

Bioinformatics News and Research

Further Reading

Researchers receive $2.95 million grant to create improved diagnostics for worm infections

Researchers develop a gene signature for predicting survival in patients with peritoneal carcinomatosis

Researchers discover protein crucial to T cell metabolism and anti-tumor immune response

Six clearly distinguishable subtypes of prediabetes identified

Certain aquatic insects can forewarn against possible outbreaks of diarrheal disease, shows study

A handy reference on pollution

Immunologic modeling of COVID-19 severity and chronicity

SARS-CoV-2 infection shown to reduce the expression of vitamin D pathway components

SARS-CoV-2 mutations may evade T cell immunity

Novel 3D maps show how genes interact in several types of immune cells

£6.7m awarded to find new ways to improve prevention, diagnosis and treatment of diseases

Researchers investigate microbiome-mediated therapies for aging and health span

Researchers discover cells responsible for resistance to T-ALL treatment

Researchers identify key gene necessary for cells to consume and destroy viruses

A new approach to identify genomic regions in our brain that contribute to make us human

Scientists identify new Salmonella proteins

SARS-CoV-2 unique deletion variants found in clinical specimens

Prior T cell immunity to SARS-CoV-2 unlikely to be the result of seasonal coronavirus infection

Study unlocks some muscle cell secrets

Research provides new insights into Glioblastoma invasiveness

eBook: A guide to RNA sequencing eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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